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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
dienophile
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "dienophile" in MCE Product Catalog:
1
1 Cited Publications
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2-Nitrosopyridine is a nitroso compound that can be used to synthesize antibiotics. 2-Nitrosopyridine can be used as a Click or Diels-Alder derivatization reagent and an excellent dienophile .
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Norbornene-NHS is a norbornene-functionalized antibody-drug conjugate linker (ADC Linker) bearing an NHS ester, which is applicable for highly efficient and specific antibody conjugation reactions in ADC research and development. Norbornene-NHS also acts as an azide-group-containing click chemistry reagent, serving as a dienophile for copper-free click reaction conjugation .
Cat. No.: HY-W014081
CAS No.: 1846-76-0
Synonyms: Ethyl 2-oxo-2H-chromene-3-carboxylate
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Ethyl 3-coumarincarboxylate (Ethyl 2-oxo-2H-chromene-3-carboxylate) is a coumarin derivative and a coumarin-3-carboxylate bearing an electron-withdrawing ester substituent at the C3 position, and serves as a pseudo-template in molecularly imprinted polymers for the selective recognition of aflatoxins. Ethyl 3-coumarincarboxylate lacks antibacterial activity against Escherichia coli strains and exhibits low dienophile activity .
Cat. No.: HY-151742
CAS No.: 1986791-87-0
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Norbornene-methyl-NHS is a norbornene-based antibody-drug conjugate linker (ADC Linker) bearing methyl and NHS ester functional groups, which can be used for specific antibody conjugation. Norbornene-methyl-NHS is also a click chemistry reagent containing a TCO group, acting as a dienophile for conjugation via the Diels-Alder reaction, namely the copper-free click reaction with tetrazine .
Cat. No.: HY-151730
CAS No.: 1923268-81-8
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(Me)Tz-butanoic acid is a click chemistry reagent containing an azide. (Me)Tz-butanoic acid is tetrazine linker for conjugation via Diels-Alder-reaction, i.e. copper-free Click reaction with dienophiles . (Me)Tz-butanoic acid is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
Cat. No.: HY-W800838
CAS No.: 1466419-80-6
Cat. No.: HY-W392912A
CAS No.: 2833-24-1
Synonyms: Methyl (2E)-4-oxopent-2-enoate
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Methyl trans-4-oxo-2-pentenoate (Methyl (2E)-4-oxopent-2-enoate) is a heterofunctionalized dienophile containing both ketone and ester functional groups. The enone structure within the Methyl trans-4-oxo-2-pentenoate molecule makes it a highly reactive Michael acceptor capable of regioselective conjugate addition, which is commonly used in reactions for constructing complex ring systems such as the Robinson annulation. Methyl trans-4-oxo-2-pentenoate can serve as a substrate in the synthesis of α-(alkylmethylene) butyrolactone derivatives. Methyl trans-4-oxo-2-pentenoate participates in asymmetric Diels-Alder reactions promoted by chiral palladium complexes .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
