202 Results for "

dietary

" in MedChemExpress (MCE) Product Catalog:
Products (202)

202 Results for "dietary" in MCE Product Catalog:

25
S-Adenosyl-L-methionine
S-Adenosyl-L-methionine
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25 Publications Verification
Cat. No.: HY-B0617
CAS No.: 29908-03-0
Synonyms: S-Adenosyl methionine; Ademetionine; AdoMet
Category:  

Human Gut Microbiota Metabolites Natural Products Microorganisms Neurological Disease Endogenous metabolite Disease Research Fields Inflammation/Immunology

Target:  

Endogenous Metabolite Apoptosis

S-Adenosyl-L-methionine (S-Adenosyl methionine) is an orally active methyl group donor. S-Adenosyl-L-methionine is a dietary supplement with potent antidepressant effects. S-Adenosyl-L-methionine also has anti‑proliferative, pro‑apoptotic and anti‑metastatic roles in cancers. S-Adenosyl-L-methionine has the potential for, cancer, liver disease and osteoarthritis research .
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24
S-Adenosyl-L-methionine disulfate tosylate
S-Adenosyl-L-methionine disulfate tosylate
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24 Cited Publications
Cat. No.: HY-W017770
CAS No.: 97540-22-2
Synonyms: Ademetionine disulfate tosylate; S-Adenosyl methionine disulfate tosylate; AdoMet disulfate tosylate
Category:  

Ketones, Aldehydes, Acids Endogenous metabolite

Target:  

Endogenous Metabolite Apoptosis

S-Adenosyl-L-methionine (Ademetionine) disulfate tosylate is the disulfate tosylate form of S-Adenosyl-L-methionine (HY-B0617). S-Adenosyl-L-methionine disulfate tosylate is an orally active methyl group donor. S-Adenosyl-L-methionine disulfate tosylate is a dietary supplement with potent antidepressant effects. S-Adenosyl-L-methionine disulfate tosylate also has anti‑proliferative, pro‑apoptotic and anti‑metastatic roles in cancers. S-Adenosyl-L-methionine disulfate tosylate has the potential for, cancer, liver disease and osteoarthritis research .
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23
S-Adenosyl-L-methionine tosylate
S-Adenosyl-L-methionine tosylate
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23 Cited Publications
Cat. No.: HY-B0617A
CAS No.: 52248-03-0
Synonyms: S-Adenosyl methionine tosylate; Ademetionine tosylate; AdoMet tosylate
Category:  

Natural Products Neurological Disease Endogenous metabolite Disease Research Fields Inflammation/Immunology

Target:  

Endogenous Metabolite Apoptosis

S-Adenosyl-L-methionine (S-Adenosyl methionine) tosylate is an orally active methyl group donor. S-Adenosyl-L-methionine tosylate is a dietary supplement with potent antidepressant effects. S-Adenosyl-L-methionine tosylate also has anti‑proliferative, pro‑apoptotic and anti‑metastatic roles in cancers. S-Adenosyl-L-methionine tosylate has the potential for, cancer, liver disease and osteoarthritis research .
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21
Astaxanthin
Astaxanthin
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21 Cited Publications
Cat. No.: HY-B2163
CAS No.: 472-61-7
Category:  

Cardiovascular Disease Anti-aging Whitening Agent Research on Agricultural Breeding Food Research Agricultural Research Microorganisms Sunscreen Terpenoids Pigments Diterpenoids Cosmetic Research Disease Research Fields

Target:  

PPAR Reactive Oxygen Species (ROS) STAT NF-κB Apoptosis

Astaxanthin, the red dietary carotenoid, is an orally effective and potent antioxidant. Astaxanthin inhibits NF-κB and down-regulates VEGF in blood glucose. Astaxanthin exerts anti-cancer cell proliferation, increases apoptosis, impairs migration and invasion by activating PPARγ and reducing the expression of STAT3. Astaxanthin also has neuroprotective and anti-inflammatory activity and can be used in studies of cancer, diabetic retinopathy, cardiovascular disease, and in the coloring of animal feed .
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19
S-Adenosyl-L-methionine iodide
S-Adenosyl-L-methionine iodide
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19 Cited Publications
Cat. No.: HY-14614D
CAS No.: 3493-13-8
Synonyms: S-Adenosyl methionine iodide; Ademetionine iodide; AdoMet iodide
Category:  

Natural Products Metabolic Disease Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite Apoptosis

S-Adenosyl-L-methionine (S-Adenosyl methionine) iodide is an orally active methyl group donor. S-Adenosyl-L-methionine iodide is a dietary supplement with potent antidepressant effects. S-Adenosyl-L-methionine iodide also has anti‑proliferative, pro‑apoptotic and anti‑metastatic roles in cancers. S-Adenosyl-L-methionine iodide has the potential for, cancer, liver disease and osteoarthritis research .
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13
Glucosamine
Glucosamine
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13 Cited Publications
Cat. No.: HY-B1125
CAS No.: 3416-24-8
Synonyms: D-Glucosamine; Chitosamine
Category:  

Human Gut Microbiota Metabolites Anti-aging Endogenous metabolite Disease Research Fields Inflammation/Immunology Saccharides Cancer Monosaccharides

Target:  

CFTR Free Radical Scavengers Endogenous Metabolite Reactive Oxygen Species (ROS) HIF/HIF Prolyl-Hydroxylase Autophagy

Glucosamine (D-Glucosamine) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a dietary supplement. Glucosamine also is a natural constituent of glycosaminoglycans in the cartilage matrix and synovial fluid, which when administered exogenously, exerts pharmacological effects on osteoarthritic cartilage and chondrocytes .
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13
Trimethylamine N-oxide
Trimethylamine N-oxide
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13 Cited Publications
Cat. No.: HY-116084
CAS No.: 1184-78-7
Purity:  ≥98.0%
Category:  

Cardiovascular Disease Natural Products Microorganisms Other disease Disease markers Endogenous metabolite Disease Research Fields Inflammation/Immunology Cancer

Target:  

Drug Metabolite NOD-like Receptor (NLR) Reactive Oxygen Species (ROS) TGF-beta/Smad Endogenous Metabolite

Trimethylamine N-oxide is a gut microbe-dependent metabolite of dietary choline and other trimethylamine-containing nutrients. Trimethylamine N-oxide induces inflammation by activating the ROS/NLRP3 inflammasome. Trimethylamine N-oxide also accelerates fibroblast-myofibroblast differentiation and induces cardiac fibrosis by activating the TGF-β/smad2 signaling pathway .
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13
Glucosamine hydrochloride
Glucosamine hydrochloride
0 Images
13 Cited Publications
Cat. No.: HY-N0733
CAS No.: 66-84-2
Synonyms: D-(+)-Glucosamine hydrochloride; Chitosamine hydrochloride
Category:  

Microorganisms Animals Endogenous metabolite Disease Research Fields Saccharides Cancer

Target:  

Free Radical Scavengers Endogenous Metabolite Reactive Oxygen Species (ROS) HIF/HIF Prolyl-Hydroxylase Autophagy

Glucosamine hydrochloride (D-Glucosamine hydrochloride) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a dietary supplement. Glucosamine hydrochloride also is a natural constituent of glycosaminoglycans in the cartilage matrix and synovial fluid, which when administered exogenously, exerts pharmacological effects on osteoarthritic cartilage and chondrocytes .
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13
Glucosamine sulfate
Glucosamine sulfate
0 Images
13 Cited Publications
Cat. No.: HY-N0487
CAS No.: 29031-19-4
Synonyms: D-Glucosamine sulfate
Category:  

Endogenous metabolite Disease Research Fields Saccharides Cancer

Target:  

Free Radical Scavengers Endogenous Metabolite Reactive Oxygen Species (ROS) HIF/HIF Prolyl-Hydroxylase Autophagy

Glucosamine sulfate (D-Glucosamine sulfate) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a dietary supplement. Glucosamine sulfate also is a natural constituent of glycosaminoglycans in the cartilage matrix and synovial fluid, which when administered exogenously, exerts pharmacological effects on osteoarthritic cartilage and chondrocytes .
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13
Trimethylamine N-oxide dihydrate
Trimethylamine N-oxide dihydrate
0 Images
13 Cited Publications
Cat. No.: HY-108915
CAS No.: 62637-93-8
Purity:  ≥98.0%
Category:  

Natural Products Metabolic Disease Endogenous metabolite Disease Research Fields

Target:  

NOD-like Receptor (NLR) Reactive Oxygen Species (ROS) TGF-beta/Smad Endogenous Metabolite

Trimethylamine N-oxide dihydrate is a gut microbe-dependent metabolite of dietary choline and other trimethylamine-containing nutrients. Trimethylamine N-oxide dihydrate induces inflammation by activating the ROS/NLRP3 inflammasome. Trimethylamine N-oxide dihydrate also accelerates fibroblast-myofibroblast differentiation and induces cardiac fibrosis by activating the TGF-β/smad2 signaling pathway .
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12
alpha-Mangostin
alpha-Mangostin
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12 Cited Publications
Cat. No.: HY-N0328
CAS No.: 6147-11-1
Synonyms: α-Mangostin
Category:  

Xanthones Phenols Polyphenols Plants Other Families Extract Disease Research Fields Cancer

Target:  

Reactive Oxygen Species (ROS) Apoptosis Bacterial Fungal Virus Protease

alpha-Mangostin (α-Mangostin) is a dietary xanthone with broad biological activities, such as antioxidant, anti-allergic, antiviral, antibacterial, anti-inflammatory and anticancer effects. It is an inhibitor of mutant IDH1 (IDH1-R132H) with a Ki of 2.85 μM.
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12
S-Adenosyl-L-methionine chloride dihydrochloride
S-Adenosyl-L-methionine chloride dihydrochloride
0 Images
12 Cited Publications
Cat. No.: HY-14614A
CAS No.: 86867-01-8
Purity:  ≥75.0%
Synonyms: S-Adenosyl methionine chloride dihydrochloride; Ademetionine chloride dihydrochloride; AdoMet chloride dihydrochloride
Target:  

Endogenous Metabolite Apoptosis

Research Areas:  

Neurological Disease Inflammation/Immunology Cancer

S-Adenosyl-L-methionine (S-Adenosyl methionine) chloride dihydrochloride is an orally active methyl group donor. S-Adenosyl-L-methionine chloride dihydrochloride is a dietary supplement with potent antidepressant effects. S-Adenosyl-L-methionine chloride dihydrochloride also has anti‑proliferative, pro‑apoptotic and anti‑metastatic roles in cancers. S-Adenosyl-L-methionine chloride dihydrochloride has the potential for, cancer, liver disease and osteoarthritis research .
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11
Aldosterone
Aldosterone
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11 Cited Publications
Cat. No.: HY-113313
CAS No.: 52-39-1
Purity:  98.93%
Category:  

Cardiovascular Disease Endogenous metabolite Disease Research Fields Steroids

Target:  

Endogenous Metabolite

Aldosterone is the primary mineralocorticoid. Aldosterone is a steroid hormone, and it is synthesized and secreted in response to renin-angiotensin system activation (RAS) or high dietary potassium by the zona glomerulosa (ZG) of the adrenal cortex. Aldosterone activity is dependent by the binding and activation of the cytoplasmic/nuclear mineralocorticoid receptor (MR) at cellular level .
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7
Betaine
Betaine
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7 Cited Publications
Cat. No.: HY-B0710
CAS No.: 107-43-7
Synonyms: Trimethylglycine; carboxy-N,N,N-trimethylmethanaminium
Category:  

Natural Products Microorganisms Animals Disease markers Metabolic Disease Plants Other Families Extract Endogenous metabolite Disease Research Fields Cancer

Target:  

Environmental Pollutants Endogenous Metabolite

Betaine (Trimethylglycine) is a natural compound found in many foods and also an active methyl-donor which can maintain normal DNA methylation patterns [1,2]. Betaine is found ubiquitously in plants, animals, microorganisms, and rich dietary sources including seafood, spinach, and wheat bran. Betaine also acts as an osmolyte, to maintain the avian’s cellular water and ion balance to improve the avian’s capacity against heat stress via preventing dehydration and osmotic inactivation. It helps in maintaining the protective osmolytic activity, especially in heat-stressed birds. Betaine may promote various intestinal microbes against osmotic variations and thus improve microbial fermentation activity .
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5
L-SelenoMethionine
L-SelenoMethionine
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5 Cited Publications
Cat. No.: HY-B1000A
CAS No.: 3211-76-5
Synonyms: L-SeMet
Category:  

Microorganisms Animals Ketones, Aldehydes, Acids Plants Other Families Extract Endogenous metabolite Disease Research Fields Cancer

Target:  

Endogenous Metabolite Apoptosis

L-SelenoMethionine, an L-isomer of Selenomethionine, is a major natural food-form of selenium. L-SelenoMethionin is a cancer chemopreventive agent that can reduce cancer incidence by dietary supplementation and induce apoptosis of cancer cells. L-SelenoMethionine also can increase expression of glutathione peroxidase .
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5
Malic acid disodium salt
Malic acid disodium salt
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5 Cited Publications
Cat. No.: HY-W250303
CAS No.: 676-46-0
Synonyms: Hydroxybutanedioic acid disodium salt; E 296 disodium salt
Sodium DL-Malate is an organic compound commonly used as a food additive, buffer and nutritional supplement. It contains sodium and malic acid. Malic acid disodium salt has several properties suitable for these applications, including the ability to enhance food flavor, improve texture and regulate acidity. Additionally, it can be used as a dietary supplement due to its potential health benefits, including improved energy production, reduced fatigue, and enhanced athletic performance.
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5
Malic acid disodium hydrate
Malic acid disodium hydrate
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5 Cited Publications
Cat. No.: HY-W250303A
CAS No.: 63474-37-3
Synonyms: Hydroxybutanedioic acid disodium hydrate; Disodium DL-malate hydrate; E 296 disodium hydrate
Malic acid disodium hydrate is an organic compound that is commonly used as a food additive, buffering agent, and nutritional supplement. It contains sodium and malic acid. Malic acid disodium hydrate has a variety of properties that make it suitable for these applications, including the ability to enhance food flavor, improve texture, and regulate acidity. In addition, due to its potential health benefits, including improved energy production, reduced fatigue, and enhanced athletic performance, Malic acid disodium hydrate can be used as a dietary supplement .
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5
Isorhapontigenin
Isorhapontigenin
0 Images
5 Cited Publications
Cat. No.: HY-N2593
CAS No.: 32507-66-7
Category:  

Gnetaceae Extract Stilbenes Gnetum cleistostachyum C. Y. Cheng Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology

Target:  

Carnitine Palmitoyltransferase (CPT) Reactive Oxygen Species (ROS) Autophagy Apoptosis NF-κB PI3K Akt MMP Keap1-Nrf2

Isorhapontigenin is an orally active dietary polyphenol. Isorhapontigenin acts as a potent antioxidant that reduces the production of reactive oxygen species (ROS). Isorhapontigenin promotes the binding of JUN to the AP-1 site on the SESN2 promoter, induces SESN2 transcription, triggers MAPK8-dependent JUN activation, and upregulates the expression of PPAR-α, PGC-1α and CPT-1A to facilitate fatty acid oxidation. Isorhapontigenin induces autophagy, apoptosis and preadipocyte differentiation; it inhibits tumor growth, cell invasion, NF-κB transcriptional activity, the PI3K/Akt signaling pathway, STAT1 phosphorylation and MMP-2 expression. Isorhapontigenin alleviates oxidative stress, inflammatory cytokine release and triglyceride accumulation; it increases intracellular ATP levels and promotes Nrf2 nuclear translocation. Isorhapontigenin improves insulin sensitivity in adipose tissue and glucose tolerance, and reduces postprandial blood glucose, insulin and free fatty acid levels. Isorhapontigenin is applicable to research on bladder cancer, liver injury, chronic obstructive pulmonary disease, acute lung injury and type 2 diabetes .
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4
Inosinic acid
Inosinic acid
0 Images
4 Cited Publications
Cat. No.: HY-108213
CAS No.: 131-99-7
Purity:  99.81%
Synonyms: 5'-IMP; IMP; Inosine 5'-dihydrogen phosphate
Category:  

Microorganisms Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite

Inosinic acid is an endogenous metabolite. Inosinic acid is used as umami tastant, or as the dietary supplement to improve the yield and meat quality of pigs .
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4
Vitamin D2
Vitamin D2
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4 Cited Publications
Cat. No.: HY-76542
CAS No.: 50-14-6
Synonyms: Ergocalciferol; Calciferol; Ercalciol
Category:  

Human Gut Microbiota Metabolites Metabolic Disease Plants Other Families Extract Endogenous metabolite Disease Research Fields Steroids

Target:  

Environmental Pollutants Endogenous Metabolite VD/VDR

Vitamin D2 (Ergocalciferol), drived from plant sources or dietary supplements, could be used as supplement of Vitamin D .
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