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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
66 Results for "
difficile
" in MedChemExpress (MCE) Product Catalog:
Products (66)
66 Results for "difficile" in MCE Product Catalog:
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4 Cited Publications
Synonyms: ACX-362E; GLS-362E
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Ibezapolstat (ACX-362E) is a first-in-class, orally active DNA polymerase IIIC (pol IIIC) inhibitor, with a Ki of 0.325 μM for the DNA pol IIIC from C. difficile. Ibezapolstat is developed for the research of C. difficile infection(CDI) .
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Ridinilazole is a novel antibacterial with MICs range of 0.06-0.25 µg/mL (MIC90=8 µg/mL) against C. difficile.
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1 Cited Publications
Cat. No.: HY-P1137
CAS No.: 955091-53-9
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1 Cited Publications
Cat. No.: HY-P9929
CAS No.: 1246264-45-8
Synonyms: BLA761046; MBL-CDB1; MDX-1388
1
1 Cited Publications
Cat. No.: HY-P1108
CAS No.: 681260-70-8
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1 Cited Publications
Cat. No.: HY-P1108A
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CRS3123 (REP-3123) is an orally active antibacterial agent that targets methionyl-tRNA synthetase (MetRS). CRS3123 competitively displaces methionine from the active site of MetRS, preventing tRNA charging and protein synthesis, and exhibits greater selectivity for C. difficile MetRS than for human MetRS and Gram-negative bacterial MetRS. CRS3123 can be used in research on Clostridioides difficile infection and vancomycin-resistant enterococcal infection .
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1 Cited Publications
Synonyms: REP-3123 dihydrochloride
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CRS3123 dihydrochloride (REP-3123 dihydrochloride) is an orally active antibacterial agent that targets methionyl-tRNA synthetase (MetRS). CRS3123 dihydrochloride competitively displaces methionine from the active site of MetRS, preventing tRNA charging and protein synthesis, and exhibits greater selectivity for C. difficile MetRS than for human MetRS and Gram-negative bacterial MetRS. CRS3123 dihydrochloride can be used in research on Clostridioides difficile infection and vancomycin-resistant enterococcal infection .
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1 Cited Publications
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ATPase-IN-2 is an ATPase inhibitor with an IC50 value of 0.9 μM. ATPase-IN-2 inhibits C. difficile toxin B (TcdB) glycohydrolase activity with an AC50 value of 30.91 μM. ATPase-IN-2 can be used for the research of ATP-related .
Category:
Infection Microorganisms Anti-inflammation/Immunoregulatory Antibiotics Disease Research Antibacterial Disease Research Fields Beta-lactam Antibiotics
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Penicillin V (Phenoxymethylpenicillin) is a potent and orally active antibiotic. Penicillin V shows antibacterial activity for Streptococci, Clostridium difficile and staphylococcus aureus. Penicillin V has the potential for the research of otitis, sinusitis, pharyngitis and tonsillitis .
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Synonyms: ACT-179811
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Cadazolid (ACT-179811) is a new oxazolidinone antibiotic with potent activity against Clostridium difficile.
Synonyms: Reutericycline
Category:
Infection Microorganisms Antibiotics Disease Research Antibacterial Disease Research Fields Other Antibiotics
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Cat. No.: HY-17580S
CAS No.: 2143934-06-7
Synonyms: KRM-1648; ABI-1648
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Rifalazil (KRM-1648; ABI-1648), a rifamycin derivative, inhibits the bacterial DNA-dependent RNA polymerase and kills bacterial cells by blocking off the β-subunit in RNA polymerase . Rifalazil (KRM-1648; ABI-1648) is an antibiotic, exhibits high potency against mycobacteria, gram-positive bacteria, Helicobacter pylori, C. pneumoniae and C. trachomatis with MIC values from 0.00025 to 0.0025 μg/ml . Rifalazil (KRM-1648; ABI-1648) has the potential for the treatment of Chlamydia infection, Clostridium difficile associated diarrhea (CDAD), and tuberculosis (TB) .
Cat. No.: HY-P99277
CAS No.: 1245634-25-6
Synonyms: Anti-C. difficile Toxin A Recombinant Antibody
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
