526 Results for "

dimeric fluorogenic aptamers

" in MedChemExpress (MCE) Product Catalog:
Products (526)

526 Results for "dimeric fluorogenic aptamers" in MCE Product Catalog:

21
21 Publications Verification
Cat. No.: HY-110251
CAS No.: 1539318-36-9
Purity:  98.11%
DFHBI-1T is a membrane-permeable RNA aptamers-activated fluorescence probe (ex/em=472 nm/507 nm). DFHBI-1T binds to RNA aptamers (Spinach, Spinach2, iSpinach, and Broccoli) and causes specific fluorescence and lower background fluorescence. DFHBI-1T is used to image RNA in live cells .
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17
17 Cited Publications
Cat. No.: HY-P1002
CAS No.: 94367-21-2
Synonyms: Suc-LLVY-AMC
Research Areas:  

Others

Suc-Leu-Leu-Val-Tyr-AMC is a membrane-permeable calpain-specific fluorogenic substrate (Ex/Em = 390/480 nm) .
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16
16 Cited Publications
Cat. No.: HY-108847
CAS No.: 185243-69-0
Purity:  99.20%

Target:  

TNF Receptor Bacterial

Research Areas:  

Inflammation/Immunology Cancer

Etanercept, a dimeric fusion protein that binds TNF, acts as a TNF inhibitor. Etanercept competitively inhibits the binding of both TNF-α and TNF-β to cell surface TNF receptors, rendering TNF biologically inactive. Etanercept shows efficacy against rheumatoid arthritis, juvenile idiopathic arthritis, and plaque psoriasis .
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13
13 Cited Publications
Cat. No.: HY-P1005
CAS No.: 201608-14-2
Target:  

Fluorescent Dye

Research Areas:  

Cancer

Ac-DEVD-AFC is a fluorogenic substrate (λex=400 nm, λem=530 nm).
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12
12 Cited Publications
Cat. No.: HY-D0719
CAS No.: 596-09-8
Synonyms: 3,6-Diacetoxyfluoran; Di-O-acetylfluorescein
Fluorescein diacetate is a cell permeable esterase-substrate. Fluorescein diacetate can be used as a fluorogenic substrate for hGSTP1-1.
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11
11 Cited Publications
Cat. No.: HY-P0019
CAS No.: 66216-78-2
Research Areas:  

Cardiovascular Disease

Z-Gly-Gly-Arg-AMC is a thrombin-specific fluorogenic substrate for testing of thrombin generation in PRP and platelet-poor plasma (PPP) (Ex/Em = 390/480 nm) .
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11
11 Cited Publications
Cat. No.: HY-P0019A
CAS No.: 2070009-61-7
Research Areas:  

Others

Z-Gly-Gly-Arg-AMC acetate is a thrombin-specific fluorogenic substrate for testing of thrombin generation in PRP and platelet-poor plasma (PPP) (Ex/Em = 390/480 nm) .
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10
10 Cited Publications
Cat. No.: HY-D0844
CAS No.: 27025-41-8
Synonyms: L-Glutathione oxidized; GSSG; Oxiglutatione
Glutathione oxidized (L-Glutathione oxidized) is produced by the oxidation of glutathione. Detoxification of reactive oxygen species is accompanied by production of glutathione oxidized. Glutathione oxidized can be used for the research of sickle cells and erythrocytes .
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7
7 Cited Publications
Cat. No.: HY-101895
CAS No.: 17817-20-8
Purity:  99.81%
Synonyms: FDG
Fluorescein di(β-D-galactopyranoside) is a fluorogenic substrate for β-galactosidase (λex=485 nm, λem=535 nm).
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6
6 Cited Publications
Cat. No.: HY-117468
CAS No.: 2609-88-3
Purity:  98.00%
Target:  

Fluorescent Dye

Research Areas:  

Others

Lissamine rhodamine B is a red-fluorescent dye, it is a derivative of rhodamine. Lissamine rhodamine B can be used as a fluorescent probe to develop competitive aptamer fluorescence anisotropy/polarization (FA/FP) assays .
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4
4 Cited Publications
Cat. No.: HY-D1670
CAS No.: 68542-93-8
Z-Gly-Pro-AMC is a fluorogenic substrate. Z-Gly-Pro-AMC is hydrolyzed by prolyl endopeptidase to generate highly fluorescent 7-Amino-4-methylcoumarin (HY-D0027). (λex=380 nm, λem=465 nm) .
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4
4 Cited Publications
Cat. No.: HY-D1373
CAS No.: 156840-13-0
Synonyms: HBC 530
HBC (HBC 530) is a GFP fluorophore-like synthetic dye, with a structurally rigid electron acceptor and a strong electron donor. HBC has a low fluorescence background, and when combined with Pepper (RNA aptamer), HBC forms a tight complex and activates and emits bright fluorescence (Kd of ~3.5 nM). HBC emission peaks vary in different complexes and covers the spectrum from cyan to red. HBC can be used in the live cell imaging of RNA (Em/Ex = 530/485 nm) .
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3
3 Cited Publications
Cat. No.: HY-101880
CAS No.: 119171-73-2
Purity:  99.67%
Synonyms: 10-Acetyl-3,7-dihydroxyphenoxazine
ADHP is a fluorogenic peroxidase substrate (λex=530 nm, λem=590 nm).
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3
3 Cited Publications
Cat. No.: HY-D1080
CAS No.: 50402-56-7
Synonyms: 1,5-EDANS
EDANS (1,5-EDANS) is a novel and quenched fluorogenic substrate for assaying retroviral protease by resonance energy transfer (RET) .
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3
3 Cited Publications
Cat. No.: HY-P2295
Target:  

SARS-CoV

Research Areas:  

Others

Dabcyl-KTSAVLQSGFRKME-Edans TFA is a fluorogenic peptide. Dabcyl-KTSAVLQSGFRKME-Edans TFA is used as the substrate to measure the enzymatic activities of protease forms. Dabcyl-KTSAVLQSGFRKME-Edans TFA has the potential for study 2019-nCoV (COVID-19) infection .
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3
3 Cited Publications
Cat. No.: HY-114816
CAS No.: 67605-85-0
Purity:  98.77%
Synonyms: C4-HSL; N-Butyryl-L-homoserine lactone
Target:  

ADC Linkers Bacterial

Research Areas:  

Infection Inflammation/Immunology

N-Butanoyl-L-homoserine lactone (C4-HSL) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Butanoyl-L-homoserine lactone has antibacterial activity and is used in antibacterial biofilm . N-Butanoyl-L-homoserine lactone aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa .
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3
3 Cited Publications
Cat. No.: HY-147081
CAS No.: 301636-59-9
Purity:  99.52%
Synonyms: AGRO-100
Research Areas:  

Cancer

AS 1411 (AGRO-100) is an oligonucleotide aptamer targeting nucleoproteins. AS 1411 inhibits tumor cell proliferation by affecting the activity of nucleoprotein-containing complexes and can be used as a carrier to precisely deliver nanoparticles, oligonucleotides and small molecules to cancer cells. AS 1411 reduces PRMT5 expression to inhibit tumor growth in DU145 prostate cancer cells. AS 1411 works by blocking the binding of nucleoproteins to bcl-2 mRNA in MCF-7 breast cancer cells. AS 1411-coupled Jin nanospheres can inhibit breast cancer cell proliferation in vitro and in mouse models, has the ability to cross the blood-brain barrier with low tissue toxicity .
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3
3 Cited Publications
Cat. No.: HY-147081A
Synonyms: AGRO-100 sodium
Research Areas:  

Cancer

AS 1411 (AGRO-100) sodium is an oligonucleotide aptamer targeting nucleoproteins. AS 1411 sodium inhibits tumor cell proliferation by affecting the activity of nucleoprotein-containing complexes and can be used as a carrier to precisely deliver nanoparticles, oligonucleotides and small molecules to cancer cells. AS 1411 sodium reduces PRMT5 expression to inhibit tumor growth in DU145 prostate cancer cells. S 1411 sodium works by blocking the binding of nucleoproteins to bcl-2 mRNA in MCF-7 breast cancer cells. S 1411 sodium-coupled Jin nanospheres can inhibit breast cancer cell proliferation in vitro and in mouse models, has the ability to cross the blood-brain barrier with low tissue toxicity
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2
2 Cited Publications
Cat. No.: HY-W073524
CAS No.: 1420815-55-9
DFAME is a red fluorophore (Ex = 508 nm, Em = 641 nm). DFAME binds to Beetroot and Corn (dimeric fluorescent RNA aptamers) to form Beetroot-DFAME (Kd = 460 nM) and Corn-DFAME (Kd = 3600 nM). Beetroot-DFAME and Corn-DFAME can be used to form RNA assemblies in living cells. Creating RNA assemblies can be used for the study of RNA Nanostructures. DNA/RNA Nanostructures would be useful in cell and gene therapy (CGT) research .
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2
2 Cited Publications
Cat. No.: HY-D1252
CAS No.: 2966536-18-3
Fast-TRFS is a selective and superfast fluorogenic probe of thioredoxin reductase (TrxR). Fast-TRFS can be used for imaging TrxR activity in live cells .
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