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212 Results for "

dioxygenase

" in MedChemExpress (MCE) Product Catalog:

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110

3-TYP

110 Publications Verification

Cat. No.: HY-108331

CAS No.: 120241-79-4

Purity: 99.96%

Target:

Sirtuin Methionine Adenosyltransferase (MAT) Indoleamine 2,3-Dioxygenase (IDO)

Research Areas:

Cancer

3-TYP is an inhibitor of SIRT3 (IC₅₀of 38 μM) and an inhibitor of Methionine Adenosyltransferase (MAT) 2 and Indoleamine 2,3-Dioxygenase (IDO). There may be many off-target sites for 3-TYP that need to be examined, such as NAD-dependent enzymes, including dehydrogenases .

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Navoximod

13 Cited Publications

Cat. No.: HY-18770B

CAS No.: 1402837-78-8

Synonyms: GDC-0919; NLG-919

Target:

Indoleamine 2,3-Dioxygenase (IDO)

Research Areas:

Cancer

Navoximod (GDC-0919; NLG-?919) is a potent IDO (indoleamine-(2,3)-dioxygenase) pathway inhibitor with K_i/EC₅₀ of 7 nM/75 nM.

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Indoximod

12 Cited Publications

Cat. No.: HY-16724

CAS No.: 110117-83-4

Synonyms: 1-Methyl-D-tryptophan; NLG-8189

Target:

Indoleamine 2,3-Dioxygenase (IDO)

Research Areas:

Cancer

Indoximod (1-Methyl-D-tryptophan) is an orally active indoleamine 2,3-dioxygenase (IDO) pathway inhibitor. Indoximod acts as a Trp mimetic in regulating mTOR. Indoximod is an immunometabolic adjuvant used for the research of cancer .

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