76 Results for "

dipeptidase

" in MedChemExpress (MCE) Product Catalog:
Products (76)

76 Results for "dipeptidase" in MCE Product Catalog:

42
42 Publications Verification
Cat. No.: HY-13233A
CAS No.: 150080-09-4
Purity:  98.35%
Synonyms: Val-boroPro mesylate; PT100 mesylate
Target:  

Dipeptidyl Peptidase

Research Areas:  

Inflammation/Immunology Cancer

Talabostat mesylate (Val-boroPro mesylate; PT100 mesylate) is an orally active and nonselective dipeptidyl peptidase IV (DPP-IV) inhibitor (IC50 < 4 nM; Ki = 0.18 nM) and the inhibitor of fibroblast activation protein (FAP) (IC50 = 560 nM), inhibits DPP8/9 (IC50 = 4/11 nM; Ki = 1.5/0.76 nM), quiescent cell proline dipeptidase (QPP) (IC50 = 310 nM), DPP2, and some other DASH family enzymes. Antineoplastic and hematopoiesis- stimulating activities .
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2
2 Cited Publications
Cat. No.: HY-P7992
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ACE; Angiotensin I Converting Enzyme (Peptidyl-dipeptidase A) 1; Prev. DCP1; DCP; Angiotensin-Converting Enzyme; Dipeptidyl Carboxypeptidase 1; Dipeptidyl Carboxypeptidase I; Angiotensin Converting Enzyme; Kininase II; Peptidyl-dipeptidase A; CD143; Carbo
Species:  
Human
Source:  
E. coli
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2
2 Cited Publications
Cat. No.: HY-P7441
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ACE2; Angiotensin I Converting Enzyme 2; Angiotensin Converting Enzyme 2; Angiotensin-Converting Enzyme 2; ACEH; ACE-Related Carboxypeptidase; Angiotensin I Converting Enzyme (Peptidyl-dipeptidase A) 2; Metalloprotease MPROT15; Angiotensin-Converting Enzy
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-D0889
CAS No.: 556-50-3
Synonyms: Gly-Gly; H-Gly-Gly-OH
Glycylglycine is a non-selective glycylglycine dipeptidase substrate and iNOS inhibitor. Glycylglycine can cross the cell membrane by passive diffusion and is hydrolyzed to glycine in the cell, participating in energy metabolism and antioxidant processes. Glycylglycine promotes spermatogonial stem cells (SSCs) proliferation, inhibits astrocyte overactivation and reduces nitric oxide (NO) release, while upregulating the expression of neurotrophic factors (such as PDGFA, FGF2, CNTF) to support nerve myelin repair. Glycylglycine can be used to study male reproductive biology (such as SSCs proliferation regulation) and neurodegenerative diseases (such as neuroprotective mechanisms in multiple sclerosis) .
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1
1 Cited Publications
Cat. No.: HY-113465
CAS No.: 75715-89-8
Purity:  99.80%
Synonyms: LTE4
Leukotriene E4 (LTE4) is produced by the action of dipeptidase on LTD4. Leukotriene E4 is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A). Leukotriene E4 accumulates in both plasma and urine and urinary excretion of Leukotriene E4 is most often used as an indicator of asthma.
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1
1 Cited Publications
Cat. No.: HY-P76837
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CNDP2; Glutamate Carboxypeptidase-Like Protein 1; Prev. PEPA; Carnosine dipeptidase II; CPGL; CNDP dipeptidase 2; CN2; Carnosinase-2; Cytosolic Non-Specific dipeptidase; FLJ10830; Threonyl dipeptidase; HEL-S-13; Peptidase A; Epididymis Secretory Protein Li 13; HsT2298; Alternative Protein CNDP2; CNDP dipeptidase 2 (Metallopeptidase M20 Family); Carnosine dipeptidase 2; Cytosolic Nonspecific dipeptidase
Species:  
Human
Source:  
Sf9 insect cells
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1
1 Cited Publications
Cat. No.: HY-P7442
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ACE2; Angiotensin I Converting Enzyme 2; Angiotensin Converting Enzyme 2; Angiotensin-Converting Enzyme 2; ACEH; ACE-Related Carboxypeptidase; Angiotensin I Converting Enzyme (Peptidyl-dipeptidase A) 2; Metalloprotease MPROT15; Angiotensin-Converting Enzy
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P7443
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ACE2; Angiotensin I Converting Enzyme 2; Angiotensin Converting Enzyme 2; Angiotensin-Converting Enzyme 2; ACEH; ACE-Related Carboxypeptidase; Angiotensin I Converting Enzyme (Peptidyl-dipeptidase A) 2; Metalloprotease MPROT15; Angiotensin-Converting Enzy
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-13233
CAS No.: 149682-77-9
Synonyms: Val-boroPro; PT100
Target:  

Dipeptidyl Peptidase

Research Areas:  

Inflammation/Immunology Cancer

Talabostat (Val-boroPro; PT100) is an orally active and nonselective dipeptidyl peptidase IV (DPP-IV) inhibitor (IC50 < 4 nM; Ki = 0.18 nM) and the first clinical inhibitor of fibroblast activation protein (FAP) (IC50 = 560 nM), inhibits DPP8/9 (IC50 = 4/11 nM; Ki = 1.5/0.76 nM), quiescent cell proline dipeptidase (QPP) (IC50 = 310 nM), DPP2, and some other DASH family enzymes. Antineoplastic and hematopoiesis- stimulating activities .
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Cat. No.: HY-W016077
CAS No.: 869-19-2
Glycyl-l-leucine is a dipeptide that can be a common substrate for glycyl-leucine dipeptidase.
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Cat. No.: HY-P99506
CAS No.: 2148325-59-9
Synonyms: SC-003 mAb; SC-Mab003; SC34.28ss1

Target:  

ADC Antibodies

Research Areas:  

Cancer

Tamrintamab (SC-003 mAb, SC-Mab003, SC34.28ss1) is an ADC Antibody targeting to dipeptidase 3 (DPEP3 or MBD3). DPEP3 is a glycosyl phosphatidylinositol anchored metallopeptidase that is overexpressed in ovarian tumors. Tamrintamab can specifically bind DPEP3-expressing cells to produce cytotoxicity. Tamrintamab can be used in ovarian cancer research .
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Cat. No.: HY-D0889R
CAS No.: 556-50-3
Synonyms: Gly-Gly (Standard); H-Gly-Gly-OH (Standard)
Glycylglycine (Standard) is the analytical standard of Glycylglycine (HY-D0889). This product is intended for research and analytical applications. Glycylglycine is a non-selective glycylglycine dipeptidase substrate and iNOS inhibitor. Glycylglycine can cross the cell membrane by passive diffusion and is hydrolyzed to glycine in the cell, participating in energy metabolism and antioxidant processes. Glycylglycine promotes spermatogonial stem cells (SSCs) proliferation, inhibits astrocyte overactivation and reduces nitric oxide (NO) release, while upregulating the expression of neurotrophic factors (such as PDGFA, FGF2, CNTF) to support nerve myelin repair. Glycylglycine can be used to study male reproductive biology (such as SSCs proliferation regulation) and neurodegenerative diseases (such as neuroprotective mechanisms in multiple sclerosis) .
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Cat. No.: HY-P4559
CAS No.: 52899-08-8
Research Areas:  

Others

H-Pro-Met-OH is a dipeptide containing proline and methionine. H-Pro-Met-OH also serves as a substrate for prolinase and prolyl dipeptidase .
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Cat. No.: HY-139440
CAS No.: 56217-82-4
Purity:  99.54%
Research Areas:  

Others

DL-Leucyl-DL-phenylalanine is a dipeptide and can be used as a substrate to detecte two regions of dipeptidase staining on a gel in Drosophila simulans as well as in Drosophila melanogaster .
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Cat. No.: HY-W436471
CAS No.: 125791-92-6
Target:  

Inhibitory Antibodies

Research Areas:  

Others

H-Ala-Pro-AFC is a biological active peptide. (This is a fluorescent peptide, Abs/Em=380/500nm. It is a substrate for dipeptidyl peptidase IV (DPP IV) and Xaa-Pro dipeptidase.)
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Cat. No.: HY-P4668
CAS No.: 3989-97-7
Synonyms: Val-Leu; H-Val-Leu-OH
Target:  

Bacterial

Research Areas:  

Infection

Valylleucine (Val-Leu; H-Val-Leu-OH) is a branched-chain dipeptide that can enter cells independently via bacterial dipeptide transport systems, and is hydrolyzed by dipeptidases to release Val and Leu. Valylleucine, as a model peptide, has its α-amino pK determined to be 7.90 by combining FDNB reaction kinetics with potentiometric titration .
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Cat. No.: HY-P4668A
CAS No.: 27530-02-5
Synonyms: Val-Leu TFA; H-Val-Leu-OH TFA
Target:  

Bacterial

Research Areas:  

Infection

Valylleucine (Val-Leu; H-Val-Leu-OH) TFA is a branched-chain dipeptide that can enter cells independently via bacterial dipeptide transport systems, and is hydrolyzed by dipeptidases to release Val and Leu. Valylleucine TFA, as a model peptide, has its α-amino pK determined to be 7.90 by combining FDNB reaction kinetics with potentiometric titration .
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Cat. No.: HY-P4236
CAS No.: 34258-14-5
Target:  

Carboxypeptidase

Research Areas:  

Others

Gly-d-Phe is an affinity ligand for Thermolysin (HY-P1748) . Gly-d-Phe can be used as the substrate of membrane dipeptidase (MDP) .
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Cat. No.: HY-155027
DPP-4-IN-8 (compound 27) is a potent and selective DPP4 (dipeptidyl peptidase 4) inhibitor, with a Ki of 0.96 μM. DPP-4-IN-8 blocks the dipeptidase activity of DPP4 in both Caco-2 and HepG-2 cells. DPP-4-IN-8 also dose-dependently suppresses the expression levels of the chemokines tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), and interleukin-1β (IL-1β) .
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Cat. No.: HY-W040074
CAS No.: 23273-91-8
Synonyms: Diglycine hydrochloride hydrate; Gly-Gly (HCl H2O)
Glycylglycine hydrochloride hydrate is a non-selective Glycylglycine hydrochloride hydrate dipeptidase substrate and iNOS inhibitor. Glycylglycine hydrochloride hydrate can cross the cell membrane by passive diffusion and is hydrolyzed to glycine in the cell, participating in energy metabolism and antioxidant processes. Glycylglycine hydrochloride hydrate promotes spermatogonial stem cells (SSCs) proliferation, inhibits astrocyte overactivation and reduces nitric oxide (NO) release, while upregulating the expression of neurotrophic factors (such as PDGFA, FGF2, CNTF) to support nerve myelin repair. Glycylglycine hydrochloride hydrate can be used to study male reproductive biology (such as SSCs proliferation regulation) and neurodegenerative diseases (such as neuroprotective mechanisms in multiple sclerosis) .
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