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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
152 Results for "
dominant
" in MedChemExpress (MCE) Product Catalog:
Products (152)
152 Results for "dominant" in MCE Product Catalog:
4
4 Cited Publications
Cat. No.: HY-16743
CAS No.: 1401090-53-6
Synonyms: Venglustat; SAR402671; GZ402671
Target:
Research Areas:
Ibiglustat (Venglustat) is an orally active, brain-penetrant glucosylceramide synthase (GCS) inhibitor. Ibiglustat can be used for the research of Gaucher disease type 3, Parkinson's disease associated with GBA mutations, Fabry disease, GM2 gangliosidosis, and autosomal dominant polycystic kidney disease .
4
4 Cited Publications
Cat. No.: HY-16743A
CAS No.: 1629063-78-0
Synonyms: Venglustat (L-Malic acid); SAR402671 (L-Malic acid); GZ402671 (L-Malic acid)
Target:
Research Areas:
Ibiglustat (Venglustat) L-Malic acid is an orally active, brain-penetrant glucosylceramide synthase (GCS) inhibitor. Ibiglustat L-Malic acid can be used for the research of Gaucher disease type 3, Parkinson's disease associated with GBA mutations, Fabry disease, GM2 gangliosidosis, and autosomal dominant polycystic kidney disease .
4
4 Cited Publications
Cat. No.: HY-16743B
CAS No.: 1629063-80-4
Synonyms: Venglustat succinate; SAR402671 succinate; GZ402671 succinate
Target:
Research Areas:
Ibiglustat (Venglustat) succinate is an orally active, brain-penetrant glucosylceramide synthase (GCS) inhibitor. Ibiglustat succinate can be used for the research of Gaucher disease type 3, Parkinson's disease associated with GBA mutations, Fabry disease, GM2 gangliosidosis, and autosomal dominant polycystic kidney disease .
3
3 Cited Publications
Cat. No.: HY-P70577
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SNCA; Parkinson Disease (Autosomal dominant, Lewy Body) 4; Prev. PARK1; Non-A4 Component Of Amyloid Precursor; Prev. PARK4; Non A-Beta Component Of AD Amyloid; Alpha-Synuclein; Non-A Beta Component Of AD Amyloid; NACP; Synuclein Alpha-140; PD1; I+/--Synuclein; Synuclein, Alpha (Non A4 Component Of Amyloid Precursor); Α-Synuclein; Synuclein Alpha; Non A4 Component Of Amyloid Precursor
Species:
Human
Source:
E. coli
2
2 Cited Publications
Synonyms: Streptothricin sulfate
Target:
Research Areas:
Nourseothricin sulfate (Streptothricin sulfate) is a broad-spectrum antibiotic that destroys the outer membrane of Gram-negative bacteria and is a dominant selective marker for Fonsecaea pedrosoi . Nourseothricin sulfate inhibits protein biosynthesis in prokaryotic cells and strongly inhibits the growth of eukaryotes like fungi and can also be used as a elective marker for a wide range of organisms including bacteria, yeast, filamentous fungi, and plant cells .
2
2 Cited Publications
Cat. No.: HY-P71691
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TNC; Neuronectin; Prev. HXB; Cytotactin; Prev. DFNA56; Tenascin-C; TN; MGC167029; Tenascin; GMEM; Glioma-Associated-Extracellular Matrix Antigen; TN-C; Deafness, Autosomal dominant 56; JI; Tenascin-C Additional Domain 1; Hexabrachion (Tenascin C, Cytotact
Species:
Human
Source:
E. coli
2
2 Cited Publications
Cat. No.: HY-P81101
Synonyms: COL 3A1; COL3A1; Collagen alpha 1(III) chain; Collagen III alpha 1 chain precursor; Collagen III alpha 1 polypeptide; Collagen type III alpha 1 (Ehlers Danlos syndrome type IV autosomal dominant); Collagen type III alpha 1; Collagen type III alpha; EDS4A; Ehlers Danlos syndrome type IV, autosomal dominant; Fetal collagen; Type III collagen; CO3A1_HUMAN; Collagen alpha-1(III) chain; Type III collagen; type III preprocollagen alpha 1 chain.
2
2 Cited Publications
Cat. No.: HY-P73917
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: HSPD1; HuCHA60; Prev. SPG13; CPN60; HSP60; Spastic Paraplegia 13 (Autosomal dominant); 60 KDa Heat Shock Protein, Mitochondrial; Epididymis Secretory Sperm Binding Protein; Mitochondrial Matrix Protein P1; Heat Shock 60kD Protein 1 (Chaperonin); 60 KDa Ch
Species:
Human
Source:
E. coli
1
Research Areas:
RGLS4326 (RG4326) is a microRNA-17 (miR-17) oligonucleotide inhibitor with an EC50 of 28.3 nM. RGLS4326 antagonizes AMPAR and inhibits ligand binding. RGLS4326 relieves the inhibition of Pkd1/Pkd2 by miR-17 and upregulates PC1/PC2. RGLS4326 preferentially distributes to the kidney and cysts, attenuates cyst progression and improves survival in mouse models of autosomal dominant polycystic kidney disease (ADPKD) in a miR-17 binding motif-dependent manner. RGLS4326 can be used in ADPKD-related research .
1
1 Cited Publications
Target:
1
1 Cited Publications
Cat. No.: HY-P2203
CAS No.: 2050906-89-1
Target:
Research Areas:
1
Research Areas:
RGLS4326 (RG4326) sodium is a microRNA-17 (miR-17) oligonucleotide inhibitor with an EC50 of 28.3 nM. RGLS4326 sodium antagonizes AMPAR and inhibits ligand binding. RGLS4326 sodium relieves the inhibition of Pkd1/Pkd2 by miR-17 and upregulates PC1/PC2. RGLS4326 sodium preferentially distributes to the kidney and cysts, attenuates cyst progression and improves survival in mouse models of autosomal dominant polycystic kidney disease (ADPKD) in a miR-17 binding motif-dependent manner. RGLS4326 sodium can be used in ADPKD-related research .
1
1 Cited Publications
Cat. No.: HY-148978A
CAS No.: 124262-93-7
Target:
Research Areas:
18:0,18:1 PS is the dominant phosphatidylserine subtype in cells, exosomes and HIV particles. It is abundant in the brain and is essential for maintaining membrane structure, lipid raft organization and intracellular trafficking. 18:0,18:1 PS mediates interleaflet membrane coupling through cholesterol-dependent interactions with very long-chain sphingolipids, and can induce the clustering of glycosylphosphatidylinositol-anchored proteins. In addition, clusters formed by the binding of 18:0,18:1 PS to cholesterol not only facilitate the proper distribution of cholesterol in lipid bilayers, but also effectively protect cholesterol from oxidative damage .
1
1 Cited Publications
Cat. No.: HY-P700834
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNC; Neuronectin; Prev. HXB; Cytotactin; Prev. DFNA56; Tenascin-C; TN; MGC167029; Tenascin; GMEM; Glioma-Associated-Extracellular Matrix Antigen; TN-C; Deafness, Autosomal dominant 56; JI; Tenascin-C Additional Domain 1; Hexabrachion (Tenascin C, Cytotact
Species:
Mouse
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P700002
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TNC; Neuronectin; Prev. HXB; Cytotactin; Prev. DFNA56; Tenascin-C; TN; MGC167029; Tenascin; GMEM; Glioma-Associated-Extracellular Matrix Antigen; TN-C; Deafness, Autosomal dominant 56; JI; Tenascin-C Additional Domain 1; Hexabrachion (Tenascin C, Cytotact
Species:
Mouse
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P700002A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNC; Neuronectin; Prev. HXB; Cytotactin; Prev. DFNA56; Tenascin-C; TN; MGC167029; Tenascin; GMEM; Glioma-Associated-Extracellular Matrix Antigen; TN-C; Deafness, Autosomal dominant 56; JI; Tenascin-C Additional Domain 1; Hexabrachion (Tenascin C, Cytotact
Species:
Mouse
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P71598
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: NLRP3; AII; Prev. CIAS1; Cold-Induced Autoinflammatory Syndrome 1 Protein; Prev. C1orf7; PYRIN-Containing APAF1-Like Protein 1; Prev. DFNA34; Deafness, Autosomal dominant 34; CLR1.1; Caterpiller Protein 1.1; PYPAF1; NACHT Domain-, Leucine-Rich Repeat-, An
Species:
Mouse
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P73340
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PCSK9; PC9; Prev. HCHOLA3; Hypercholesterolemia, Autosomal dominant 3; NARC-1; Neural Apoptosis Regulated Convertase 1; Subtilisin/Kexin-Like Protease PC9; Neural Apoptosis-Regulated Convertase 1; FH3; LDLCQ1; Proprotein Convertase 9; FHCL3; NARC1; Propro
Species:
Rat
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P73728
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PCSK9; PC9; Prev. HCHOLA3; Hypercholesterolemia, Autosomal dominant 3; NARC-1; Neural Apoptosis Regulated Convertase 1; Subtilisin/Kexin-Like Protease PC9; Neural Apoptosis-Regulated Convertase 1; FH3; LDLCQ1; Proprotein Convertase 9; FHCL3; NARC1; Propro
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P71189A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PCSK9; PC9; Prev. HCHOLA3; Hypercholesterolemia, Autosomal dominant 3; NARC-1; Neural Apoptosis Regulated Convertase 1; Subtilisin/Kexin-Like Protease PC9; Neural Apoptosis-Regulated Convertase 1; FH3; LDLCQ1; Proprotein Convertase 9; FHCL3; NARC1; Propro
Species:
Mouse
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
