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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
13 Results for "
dwarfism
" in MedChemExpress (MCE) Product Catalog:
Products (13)
13 Results for "dwarfism" in MCE Product Catalog:
Cat. No.: HY-P3503
CAS No.: 1480724-61-5
Synonyms: BMN 111
Target:
Research Areas:
Brassinazole (0.5, 1, 5 μM) causes markedly deformed seedlings, whose morphology is similar to that of BR-deficient mutants. Brassinazole causes cress dwarfism, altering leaf morphology such as the typical downward curl and dark green appearance of Arabidopsis BR-deficient mutants. However, administration of 10 nM BR reversed dwarfism .
Cat. No.: HY-115707
CAS No.: 126281-90-1
Synonyms: 16:0/0:0/18:3-DG; DG(16:0/0:0/18:3); 1-Palmitin-3-Linolenin
1-Palmitoyl-3-Linolenoyl-rac-glycerol (16:0/0:0/18:3-DG) is a diacylglycerol containing palmitic acid (HY-N0830) and α-linolenic acid (HY-N0728) at the sn-1 and sn-3 positions, respectively. It has been found in the peel and pulp of unripe Dwarf Cavendish bananas.
Cat. No.: HY-P5129
Target:
Research Areas:
Cat. No.: HY-176547
CAS No.: 3069945-78-1
Target:
Research Areas:
FGFR2/3-IN-3 is a dual-target FGFR2/3 inhibitor with IC50s of 2.7 nM (TEL-FGFR2) and 3.9 nM (TEL-FGFR3), respectively. FGFR2/3-IN-3 has effective activity against both wild-type and mutant FGFR3. FGFR2/3-IN-3 has low CYP3A4 inhibitory effect and hERG toxicity. FGFR2/3-IN-3 improves the imbalance between chondrocyte proliferation and differentiation and promotes bone growth by inhibiting the signaling pathway mediated by mutant FGFR3. FGFR2/3-IN-3 shows a growth-promoting effect in a dwarfism mouse model and has the potential to study bone development disorder-related diseases such as achondroplasia (ACH) .
Cat. No.: HY-131116R
CAS No.: 3572-64-3
Cat. No.: HY-P74355
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CANT1; Apyrase Homolog; Calcium Activated Nucleotidase 1; Micromelic dwarfism With Vertebral And Metaphyseal Abnormalities And Advanced Carpotarsal Ossification; SCAN-1; Ca2+-Dependent Endoplasmic Reticulum Nucleoside Diphosphatase; SHAPY; Soluble Calcium
Species:
Human
Source:
HEK293
Cat. No.: HY-P74356
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CANT1; Apyrase Homolog; Calcium Activated Nucleotidase 1; Micromelic dwarfism With Vertebral And Metaphyseal Abnormalities And Advanced Carpotarsal Ossification; SCAN-1; Ca2+-Dependent Endoplasmic Reticulum Nucleoside Diphosphatase; SHAPY; Soluble Calcium
Species:
Human
Source:
HEK293
Cat. No.: HY-P706050
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: FGFR3; Mutant Fibroblast Growth Factor Receptor 3; Prev. ACH; Fibroblast Growth Factor Receptor 3-S; JTK4; Fibroblast Growth Factor Receptor; CD333; Receptor Protein-Tyrosine Kinase; CEK2; Hydroxyaryl-Protein Kinase; FGFR-3; Tyrosine Kinase JTK4; Fibroblast Growth Factor Receptor 3 Isoform C; CD333 Antigen; Fibroblast Growth Factor Receptor 3 Isoform B; HSFGFR3EX; Fibroblast Growth Factor Receptor 3; Achondroplasia, Thanatophoric dwarfism
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P706051
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: FGFR3; Mutant Fibroblast Growth Factor Receptor 3; Prev. ACH; Fibroblast Growth Factor Receptor 3-S; JTK4; Fibroblast Growth Factor Receptor; CD333; Receptor Protein-Tyrosine Kinase; CEK2; Hydroxyaryl-Protein Kinase; FGFR-3; Tyrosine Kinase JTK4; Fibroblast Growth Factor Receptor 3 Isoform C; CD333 Antigen; Fibroblast Growth Factor Receptor 3 Isoform B; HSFGFR3EX; Fibroblast Growth Factor Receptor 3; Achondroplasia, Thanatophoric dwarfism
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P706052
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: FGFR3; Mutant Fibroblast Growth Factor Receptor 3; Prev. ACH; Fibroblast Growth Factor Receptor 3-S; JTK4; Fibroblast Growth Factor Receptor; CD333; Receptor Protein-Tyrosine Kinase; CEK2; Hydroxyaryl-Protein Kinase; FGFR-3; Tyrosine Kinase JTK4; Fibroblast Growth Factor Receptor 3 Isoform C; CD333 Antigen; Fibroblast Growth Factor Receptor 3 Isoform B; HSFGFR3EX; Fibroblast Growth Factor Receptor 3; Achondroplasia, Thanatophoric dwarfism
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P706053
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: FGFR3; Mutant Fibroblast Growth Factor Receptor 3; Prev. ACH; Fibroblast Growth Factor Receptor 3-S; JTK4; Fibroblast Growth Factor Receptor; CD333; Receptor Protein-Tyrosine Kinase; CEK2; Hydroxyaryl-Protein Kinase; FGFR-3; Tyrosine Kinase JTK4; Fibroblast Growth Factor Receptor 3 Isoform C; CD333 Antigen; Fibroblast Growth Factor Receptor 3 Isoform B; HSFGFR3EX; Fibroblast Growth Factor Receptor 3; Achondroplasia, Thanatophoric dwarfism
Species:
Human
Source:
Sf9 insect cells
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
