27

27 Publications Verification

Category:

Disease Research Antibacterial Infection Microorganisms Macrolide Antibiotics Antibiotics Animal Husbandry Mammalian Cell Culture Anticancer Disease Research Fields

Target:

Bacterial Antibiotic DNA/RNA Synthesis

Erythromycin is a macrolide antibiotic produced by actinomycete?Streptomyces erythreus?with a broad spectrum of antimicrobial activity. Erythromycin binds to bacterial 50S ribosomal subunits and inhibits?RNA-dependent protein synthesis?by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid ^[1][2]. Erythromycin also exhibits antitumor and neuroprotective effect in different fields of research ^[3][4].

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27

Erythromycin lactobionate

27 Publications Verification

Cat. No.: HY-B0220A

CAS No.: 3847-29-8

Target:

Antibiotic Bacterial DNA/RNA Synthesis

Research Areas:

Infection Cancer

Erythromycin lactobionate is a macrolide antibiotic produced by actinomycete Streptomyces erythreus with a broad spectrum of antimicrobial activity. Erythromycin lactobionate binds to bacterial 50S ribosomal subunits and inhibits RNA-dependent protein synthesis by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid ^[1][2]. Erythromycin lactobionate also exhibits antitumor and neuroprotective effect in different fields of research ^[3][4].

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27

Erythromycin thiocyanate

27 Publications Verification

Cat. No.: HY-B0220D

CAS No.: 7704-67-8

Category:

Infection Microorganisms Macrolide Antibiotics Antibiotics Disease Research Antibacterial Anticancer Disease Research Fields

Target:

Bacterial Antibiotic DNA/RNA Synthesis

Erythromycin thiocyanate is a macrolide antibiotic produced by actinomycete Streptomyces erythreus with a broad spectrum of antimicrobial activity. Erythromycin thiocyanate binds to bacterial 50S ribosomal subunits and inhibits RNA-dependent protein synthesis by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid ^[1][2]. Erythromycin thiocyanate also exhibits antitumor and neuroprotective effect in different fields of research ^[3][4].

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5

SN52

5 Cited Publications

Cat. No.: HY-P3229

CAS No.: 1071173-56-2

Target:

NF-κB

Research Areas:

Cancer

SN52 is a potent, competitive, and cell-permeable inhibitor of NF-κB2. SN52 is a variant of the SN50 peptide and inhibits the nuclear translocation of p52-RelB heterodimers. SN52 has a strong radiosensitization effect on prostate cancer cells. SN52 can be used for cancer research .

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3

STAT1/3-IN-1

3 Cited Publications

Cat. No.: HY-170621

CAS No.: 2958649-56-2

Target:

STAT NO Synthase COX Interleukin Related TNF Receptor

Research Areas:

Neurological Disease Metabolic Disease Inflammation/Immunology Cancer

STAT1/3-IN-1 is a potent STAT1/3 inhibitor with potent anti-inflammatory effect. STAT1/3-IN-1 inhibits phosphorylation and nuclear translocation of STAT1/3 to modulate microglial inflammation, reduces LPS (HY-D1056)-induced pro-inflammatory cytokines (NO, IL-1β, IL-6, and TNF-α) and inflammatory mediators (iNOS, COX-2). STAT1/3-IN-1 exhibits low toxicity in mice. STAT1/3-IN-1 can be used for the research of neuroinflammation .

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