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341 Results for "

elimination

" in MedChemExpress (MCE) Product Catalog:

Products (341)

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305

Verteporfin

305 Publications Verification

Cat. No.: HY-B0146

CAS No.: 129497-78-5

Synonyms: CL 318952

Target:

YAP Apoptosis Autophagy Photosensitizer

Research Areas:

Cancer

Verteporfin (CL 318952) is a photosensitizer for photodynamic therapy to eliminate the abnormal blood vessels in the eye associated with conditions such as age-related macular degeneration. Verteporfin is a YAP inhibitor which disrupts YAP-TEAD interactions. Verteporfin induces cell apoptosis . Verteporfinis an autophagy inhibitor that blocks autophagy at an early stage by inhibiting autophagosome formation .

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104

PLX5622 hemifumarate

104 Cited Publications

Cat. No.: HY-114153A

Purity: 99.88%

Target:

c-Fms

Research Areas:

Neurological Disease Inflammation/Immunology Cancer

PLX5622 hemifumarate is a highly selective brain penetrant and orally active CSF1R inhibitor (IC₅₀=0.016 μM; K_i=5.9 nM). PLX5622 hemifumarate allows for extended and specific microglial elimination, preceding and during pathology development. PLX5622 hemifumarate demonstrates desirable PK properties in varies animals .

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104

PLX5622

104 Cited Publications

Cat. No.: HY-114153

CAS No.: 1303420-67-8

Purity: 99.79%

Target:

c-Fms

Research Areas:

Neurological Disease Inflammation/Immunology

PLX5622 is a highly selective brain penetrant and orally active CSF1R inhibitor (IC₅₀=0.016 μM; K_i=5.9 nM). PLX5622 allows for extended and specific microglial cells elimination, preceding and during pathology development. PLX5622 is an ideal choose for microglia function research in healthy or diseased states. PLX5622 has been verified by MedChemExpress, which demonstrates desirable microglia depletion efficiency in mice. PLX5622 is predominantly administered via ad libitum diets with a dose of 1200 ppm .

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RT Master Mix for qPCR II (gDNA digester plus)

45 Cited Publications

Cat. No.: HY-K0511A

MCE RT Master Mix for qPCR II is a convenient, ready-to-use formulation for reverse transcription and can eliminate genomic DNA (gDNA) contaminations in RNA samples. With updated reverse transcriptase, this kit can synthesize cDNA more rapidly, more specifically. The 100 rxns is defined as the base specification. All larger sizes correspond to incremental volumes of this base.