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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
231 Results for "
endopeptidase
" in MedChemExpress (MCE) Product Catalog:
Products (231)
231 Results for "endopeptidase" in MCE Product Catalog:
52
Target:
Research Areas:
N-Ethylmaleimide (NEM) derives from maleic acid, it can alkylates free sulfhydryl. N-Ethylmaleimide is an irreversible cysteine protease inhibitor. N-ethylmaleimide specific inhibits phosphate transport in mitochondria. N-Ethylmaleimide inhibits prolyl endopeptidase with an IC50 value of 6.3 μM. N-Ethylmaleimide can be used to modify cysteine residues in proteins and peptides .
49
4
4 Cited Publications
Cat. No.: HY-D1670
CAS No.: 68542-93-8
3
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Racecadotril (Acetorphan) is a neutral endopeptidase (NEP) inhibitor. Racecadotril and its active metabolite Thiorphan inhibits purified NEP activity from mouse brain with Kis of 4500 and 6.1 nM, , respectively. Antidiarrheal agent .
3
3 Cited Publications
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Research Areas:
2
2 Cited Publications
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Suc-Gly-Pro-AMC is a fluorescent substrate. Suc-Gly-Pro-AMC is a fibroblast activation protein (FAP) specific substrate. Suc-Gly-Pro-AMC reacts with recombinant porcine prolyl oligopeptidase. Suc-Gly-Pro-AMC can be used to study the activity of FAP, prolyl endopeptidase (PREP). Suc-Gly-Pro-AMC is used in glioma research .
2
2 Cited Publications
Cat. No.: HY-P72659A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FAP; Prolyl endopeptidase FAP; Fibroblast Activation Protein Alpha; Dipeptidyl Peptidase FAP; Seprase; FAPalpha; DPPIV; SIMP; 170 KDa Melanoma Membrane-Bound Gelatinase; CDNA FLJ60298, Highly Similar To Seprase; Gelatine Degradation Protease FAP; Fibroblast Activation Protein, Alpha; Integral Membrane Serine Protease; Serine Integral Membrane Protease; Post-Proline Cleaving Enzyme; FAPA; Surface-Expressed Protease
Species:
Human
Source:
HEK293
1
Target:
Research Areas:
Lysostaphin is an antistaphylococcal agent. Lysostaphin has activities of three enzymes namely, glycylglycine endopeptidase, endo-β-N-acetyl glucosamidase and N-acteyl muramyl-L-alanine amidase .
1
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Lysyl endopeptidase, Achromobacter sp (Lys-C) catalyzes carboxyl oxygen exchange reaction. Lysyl endopeptidase has higher substrate binding affinities and higher catalytic rates at the acidic pHs than at the alkaline pHs .
1
1 Cited Publications
Cat. No.: HY-P4490
CAS No.: 95632-46-5
Target:
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1
1 Cited Publications
Cat. No.: HY-P4270
CAS No.: 67368-29-0
Target:
Research Areas:
1
1 Cited Publications
Cat. No.: HY-E70365
CAS No.: 2764750-38-9
Target:
Research Areas:
IdeS protease is an IgG-specific endopeptidase, which is highly specific for the lower hinge region of IgG. IdeS protease represses innate immune responses to promote streptococcal survival in an inflammatory environment .
1
1 Cited Publications
Cat. No.: HY-P703584
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PREP; PEP; Prolyl endopeptidase; PE; Post-Proline Cleaving Enzyme; DJ355L5.1 (Prolyl endopeptidase); Prolyl Oligopeptidase
Species:
Human
Source:
E. coli
1
1
Target:
Research Areas:
S 17092 (S 17092-1) is an orally active cerebral prolyl-endopeptidase (PEP) inhibitor with an IC50 of 1.2 nM. S 17092 inhibits cell apoptosis. S 17092 mechanism of action is to inhibit the activity of PEP, slowing down the degradation of neuroactive peptides and thus enhancing memory function. S 17092 can be used for the research of memory impairment and cognitive disorders associated with cerebral aging .
1
1 Cited Publications
Cat. No.: HY-P70897A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LGMN; LGMN1; Prev. PRSC1; AEP; Asparaginyl endopeptidase; Cysteine Protease 1; Protease, Cysteine 1; Legumain; Protease, Cysteine, 1 (Legumain)
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P77083
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MEP1A; Meprin A, Alpha (PABA Peptide Hydrolase); Meprin A Subunit Alpha; PPH Alpha; PABA Peptide Hydrolase; BA268F1.1 (Meprin A Alpha (PABA Peptide Hydrolase)); endopeptidase-2; Metalloendopeptidase; PPHA; Meprin A Subunit; N-Benzoyl-L-Tyrosyl-P-Amino-Ben
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P77934
Purity: ≥ 95%, as determined by reducing SDS-PAGE or Bis-Tris PAGE.
Synonyms: FAP; Prolyl endopeptidase FAP; Fibroblast Activation Protein Alpha; Dipeptidyl Peptidase FAP; Seprase; FAPalpha; DPPIV; SIMP; 170 KDa Melanoma Membrane-Bound Gelatinase; CDNA FLJ60298, Highly Similar To Seprase; Gelatine Degradation Protease FAP; Fibroblast Activation Protein, Alpha; Integral Membrane Serine Protease; Serine Integral Membrane Protease; Post-Proline Cleaving Enzyme; FAPA; Surface-Expressed Protease
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P1484
CAS No.: 23815-87-4
Synonyms: Bradykinin Fragment 1-7
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Research Areas:
Cat. No.: HY-17455
CAS No.: 68497-62-1
Synonyms: CI-879 free base
Target:
Research Areas:
Pramiracetam (CI-879 free base) is a PREP (prolyl endopeptidase) inhibitor. Pramiracetam improves cognitive impairment caused by traumatic brain injury. Pramiracetam can be used in the study of neurodegenerative diseases .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
