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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
endosomal compartments
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "endosomal compartments" in MCE Product Catalog:
Cat. No.: HY-115675
CAS No.: 568558-66-7
NC03 is a PI4K2A inhibitor and reducing agent. NC03 inhibits the activity of PI4K2A, thereby reducing the production of PI4P in the cellular compartments where PI4K2A functions. NC03 rapidly induces a decrease in PI4P pools in the Golgi and endosomal compartments. NC03 reduces PI4P production in Rab7-positive late endosomes .
Cat. No.: HY-D3383
Target:
Research Areas:
AM4-64 is a fixable cationic styryl fluorescent dye for nerve terminals, which can be used for vesicle cycle evaluation, endocytic pathway tracing and endocytosis detection. AM4-64 inserts into the plasma membrane, is internalized via activity- or energy-dependent endocytosis, and accumulates in vesicles, endosomal compartments, vacuolar membranes, mitochondria and endolysosomal structures. The fluorescence of AM4-64 is enhanced in the membrane-bound state. AM4-64 is applicable to relevant studies on neurons, plant and fungal cells and tissues (Ex/Em = 510/750 nm) .
Cat. No.: HY-P992572
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Research Areas:
Anti-Mouse 4-1BB/CD137 Antibody (17B5) is a CD137 (4-1BB/TNFRSF9)-targeting antibody .Anti-Mouse 4-1BB/CD137 Antibody (17B5) induces CD137 internalization to endosomal signaling compartments and K63-linked polyubiquitination in vivo in tumor-infiltrating lymphocytes, where endosomes costain with K63-polyubiquitin chains .Anti-Mouse 4-1BB/CD137 Antibody (17B5) can be used for the research of colon carcinoma .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
