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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
63 Results for "
endothelin-1
" in MedChemExpress (MCE) Product Catalog:
Products (63)
63 Results for "endothelin-1" in MCE Product Catalog:
33
33 Publications Verification
Cat. No.: HY-A0013
CAS No.: 147536-97-8
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Bosentan is a competitive and dual antagonist of endothelin-1 (ET) for the ETA and ETB receptors with Ki of 4.7 nM and 95 nM in human SMC, respectively.
33
33 Publications Verification
Cat. No.: HY-A0013A
CAS No.: 157212-55-0
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Bosentan hydrate is a competitive and dual antagonist of endothelin-1 (ET) for the ETA and ETB receptors with Ki of 4.7 nM and 95 nM in human SMC, respectively.
12
12 Cited Publications
Synonyms: 5-Methyl THF; 5-MTHF
Category:
Human Gut Microbiota Metabolites Ketones, Aldehydes, Acids Metabolic Disease Microorganism Endogenous metabolite Disease Research Fields
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10
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10
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4
4 Cited Publications
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4
4 Cited Publications
Cat. No.: HY-P1235A
CAS No.: 1366000-58-9
Synonyms: Atrial Natriuretic Peptide (ANP) (1-28), human, porcine acetate
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4
1
1 Cited Publications
Cat. No.: HY-P4159
CAS No.: 133972-52-8
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1
1 Cited Publications
Cat. No.: HY-P4159A
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1
1 Cited Publications
Cat. No.: HY-W042301
CAS No.: 14293-44-8
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Xipamide is an orally active carbonic anhydrase (CA) inhibitor and Na +/Cl --potassium transporter inhibitor with diuretic and antihypertensive effects. Xipamide reduces NaCl reabsorption by inhibiting the Cl -/NaCO3 - anion exchanger, and increases calcium reabsorption while promoting potassium and magnesium excretion. Xipamide is mainly cleared via the renal pathway and causes a temporary decrease in glomerular filtration rate under specific conditions. Xipamide does not affect Ca 2+ signaling induced by endothelin-1 and other factors, nor does it inhibit various ion cotransport or pump activities in red blood cells. Xipamide can be used in researches related to cardiovascular diseases, hypertension (especially with left ventricular hypertrophy), advanced renal failure, and liver cirrhosis with ascites [1] .
1
1 Cited Publications
Cat. No.: HY-113046R
CAS No.: 134-35-0
Synonyms: 5-Methyl THF (Standard); 5-MTHF (Standard)
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1 Cited Publications
Cat. No.: HY-P700460
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: EDN1; PPET1; endothelin 1; ARCND3; endothelin-1; HDLCQ7; ET1; QME; Preproendothelin-1
Species:
Human
Source:
E. coli
Cat. No.: HY-P1236
CAS No.: 88898-17-3
Synonyms: Atrial natriuretic factor (1-28) (rat, mouse)
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Cat. No.: HY-P3615
CAS No.: 138716-98-0
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[Asn18] Endothelin-1 (swine, human) is a structural analogue of Endothelin 1 (swine, human) (HY-P0202), with the Asp amino acid at position 18 mutated to Asn. Endothelin 1 (swine, human) is a synthetic peptide with human and porcine endothelin 1 sequences and is a potent endogenous vasoconstrictor [1] .
Cat. No.: HY-P2538
CAS No.: 120796-97-6
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Cat. No.: HY-P1236A
Synonyms: Atrial natriuretic factor (1-28) (rat, mouse) TFA
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Cat. No.: HY-P3733
CAS No.: 124932-61-2
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Cat. No.: HY-P11112
CAS No.: 1609454-11-6
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
