2 Results for "

enediyne

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "enediyne" in MCE Product Catalog:

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Cat. No.: HY-19791
CAS No.: 108212-76-6
Synonyms: N-Acetyl-Calicheamicin γ; N-Acetyl-γ-calicheamicin
N-Acetyl-Calicheamicin (N-Acetyl-Calicheamicin γ), an enediyne anti-tumor antibiotic, is an ADC cytotoxin. N-Acetyl-Calicheamicin can induce DNA damage, and can be used in the synthesis of ADC .
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Cat. No.: HY-188123
Target:  

PROTECs NAMPT

Research Areas:  

Cancer

NAMPT ligand-1 is a ligand targeting NAMPT, consisting of a NAMPT-binding domain, a linker, and a maleimide-fused enediyne warhead with a cyclopropane-modified alkyne terminus. NAMPT ligand-1 can be used to synthesize PROTEC NAMPT Degrader-1 (HY-189001). NAMPT ligand-1 induces the degradation of NAMPT via proximity-induced radical oxidation, and this process is independent of endogenous proteolytic mechanisms. NAMPT ligand-1 can be used in ovarian cancer research .
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