16

16 Cited Publications

Cat. No.: HY-19744

Target:

Research Areas:

T6167923 is a selective inhibitor of MyD88-dependent signaling pathways. T6167923 directly binds to Toll/IL1 receptor (TIR) domain of MyD88 and disrupts MyD88 homodimeric formation. T6167923 inhibits NF-κB driven Staphylococcus enterotoxin AP (SEAP) activity, and improves anti-inflammatory activity with IC₅₀s of 2.7 μM, 2.9 μM, 2.66 μM and 2.66 μM for IFN-γ, IL-1β, IL-6 and TNF-α, respectively .

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Z-Asp-CH2-DCB

Cat. No.: HY-113953

CAS No.: 153088-73-4

Purity: 99.64%

Target:

Caspase Apoptosis

Research Areas:

Inflammation/Immunology

Z-Asp-CH2-DCB is an irreversible broad spectrum caspase inhibitor. Z-Asp-CH2-DCB also inhibits proteases with caspase-like activity. Z-D-CH2-DCB blocks the production of IL-1β, TNF-α, IL-6, and IFN-γ in staphylococcal enterotoxin B (SEB)-stimulated peripheral blood mononuclear cells (PBMC), and reduces SEB-1-stimulated T-cell proliferation in a dose-dependent manner. Z-Asp-CH2-DCB prevents SU5416-induced septal cell apoptosis and emphysema development .

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Enterotoxin STp (E. coli)

Cat. No.: HY-P5089

CAS No.: 115474-04-9

Target:

Biochemical Assay Reagents

Research Areas:

Infection

Enterotoxin STp (E. coli) is a heat-stable enterotoxin that can be used in vaccine research .

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Enterotoxin STp (E. coli) TFA

Cat. No.: HY-P5089A

Target:

Biochemical Assay Reagents

Research Areas:

Infection

Enterotoxin STp (E. coli) TFA is a heat-stable enterotoxin that can be used in vaccine research .

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EM-163

Cat. No.: HY-163035

CAS No.: 1206480-93-4

Target:

TNF Receptor IFNAR

Research Areas:

Inflammation/Immunology

EM-163 is a summative BB-Loop analog. EM-163 can alleviate inflammation and prevent death from toxic shock by targeting the TIR domain of MyD88. EM-163 can be used in the study of SEB poisoning (SEB: Staphylococcal enterotoxin B) .

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MEGA-9

Cat. No.: HY-W040216

CAS No.: 85261-19-4

Synonyms: N-Nonanoyl-N-methylglucamine

MEGA-9 (N-Nonanoyl-N-methylglucamine) is a green, biodegradable glycosyl nonionic surfactant and micelle-forming agent. MEGA-9 acts as a membrane solubilizer, forms vesicles, solubilizes milk fat, eliminates non-specific reactions of test strips, and restores antigen-antibody reactions in cheddar cheese homogenates for the detection of staphylococcal enterotoxin B (SEB) .

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Tilivalline

Cat. No.: HY-W743944

CAS No.: 80279-24-9

Target:

Apoptosis

Research Areas:

Inflammation/Immunology

Tilivalline is an enterotoxin that can be produced by Klebsiella oxytoca. Tilivalline shows cytotoxicity against carcinoma cells. Tilivalline induces epithelial apoptosis. Tilivalline causes antibiotic-associated hemorrhagic colitis (AAHC) .

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