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675 Results for "

factor-1

" in MedChemExpress (MCE) Product Catalog:

Products (675)

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181

Pexidartinib hydrochloride

181 Publications Verification

Cat. No.: HY-16749A

CAS No.: 2040295-03-0

Synonyms: PLX-3397 hydrochloride

Target:

c-Fms c-Kit Apoptosis

Research Areas:

Cancer

Pexidartinib hydrochloride (PLX-3397 hydrochloride) is a potent, orally active, selective, and ATP-competitive colony stimulating factor 1 receptor (CSF1R or M-CSFR) and c-Kit inhibitor, with IC₅₀s of 20 and 10 nM, respectively. Pexidartinib hydrochloride exhibits 10- to 100-fold selectivity for c-Kit and CSF1R over other related kinases. Pexidartinib hydrochloride induces cell apoptosis and has anti-cancer activity ^[1].

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181

Pexidartinib

181 Publications Verification

Cat. No.: HY-16749

CAS No.: 1029044-16-3

Synonyms: PLX-3397

Target:

c-Fms c-Kit Apoptosis

Research Areas:

Cancer

Pexidartinib (PLX-3397) is a potent, orally active, selective, and ATP-competitive colony stimulating factor 1 receptor (CSF1R or M-CSFR) and c-Kit inhibitor, with IC₅₀s of 20 and 10 nM, respectively. Pexidartinib (PLX-3397) exhibits 10- to 100-fold selectivity for c-Kit and CSF1R over other related kinases. Pexidartinib (PLX-3397) induces cell apoptosis and has anti-tumor activity. Pexidartinib has limited permeability to the blood-brain barrier, primarily through ABCB1 ^[1] .

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155

M-CSF Protein, Mouse

155 Cited Publications

Cat. No.: HY-P7085

Purity: ≥ 95%, as determined by reducing SDS-PAGE.

Synonyms: CSF1; Macrophage Colony Stimulating factor 1; Colony Stimulating factor 1; Lanimostim; MCSF; MGC31930; Proteoglycan Macrophage Colony-Stimulating factor; PG-M-CSF; Macrophage Colony-Stimulating factor 1; CSF-1; M-CSF; CSF1-HERV-LTR71B Fusion Protein; Colo

Species:

Mouse

Source:

E. coli

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