3099 Results for "

fading modulator

" in MedChemExpress (MCE) Product Catalog:
Products (3099)

3099 Results for "fading modulator" in MCE Product Catalog:

307
Gemcitabine
Gemcitabine
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307 Publications Verification
Cat. No.: HY-17026
CAS No.: 95058-81-4
Synonyms: LY 188011
Target:  

Nucleoside Antimetabolite/Analog DNA/RNA Synthesis Autophagy Apoptosis p38 MAPK

Research Areas:  

Infection Inflammation/Immunology Cancer

Gemcitabine (LY 188011) is a pyrimidine nucleoside analog antimetabolite and an antineoplastic agent. Gemcitabine inhibits DNA synthesis and repair, and can modulate autophagy. Gemcitabine induces apoptosis through the activation of p38 MAPK. Gemcitabine demonstrates efficacy in mouse models of pancreatic and breast cancer. Gemcitabine can be used for cancer research, such as pancreatic cancer, non-small cell lung cancer, and breast cancer .
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282
Tamoxifen Citrate
Tamoxifen Citrate
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282 Cited Publications
Cat. No.: HY-13757
CAS No.: 54965-24-1
Purity:  99.93%
Synonyms: ICI 46474; (Z)-Tamoxifen Citrate; trans-Tamoxifen Citrate
Target:  

Estrogen Receptor/ERR HSP Autophagy Apoptosis

Research Areas:  

Infection Neurological Disease Inflammation/Immunology Cancer

Tamoxifen Citrate (ICI 46474) is an orally active, selective estrogen receptor modulator (SERM) which blocks estrogen action in breast cells and can activate estrogen activity in other cells, such as bone, liver, and uterine cells.Tamoxifen Citrate is a potent Hsp90 activator and enhances the Hsp90 molecular chaperone ATPase activity. Tamoxifen Citrate also potent inhibits infectious EBOV Zaire and Marburg (MARV) with IC50 of 0.1 μM and 1.8 μM, respectively. Tamoxifen Citrate activates autophagy and induces apoptosis. Tamoxifen Citrate can also be used to induce gene knockout in CreER transgenic mice .
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282
Tamoxifen
Tamoxifen
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282 Cited Publications
Cat. No.: HY-13757A
CAS No.: 10540-29-1
Purity:  99.78%
Synonyms: ICI 47699; (Z)-Tamoxifen; trans-Tamoxifen
Target:  

Estrogen Receptor/ERR HSP Autophagy Apoptosis

Research Areas:  

Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer

Tamoxifen (ICI 47699) is an orally active, selective estrogen receptor modulator (SERM) which blocks estrogen action in breast cells and can activate estrogen activity in other cells, such as bone, liver, and uterine cells. Tamoxifen is a potent Hsp90 activator and enhances the Hsp90 molecular chaperone ATPase activity. Tamoxifen also potent inhibits infectious EBOV Zaire and Marburg (MARV) with IC50 of 0.1 μM and 1.8 μM, respectively. Tamoxifen activates autophagy and induces apoptosis. Tamoxifen can also be dissolved in corn oil (HY-Y1888) for use in inducing gene knockout in CreER transgenic mice. Tamoxifen has better solubility in corn oil compared to Tamoxifen Citrate (HY-13757) .
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202
Rosiglitazone maleate
Rosiglitazone maleate
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202 Cited Publications
Cat. No.: HY-14600
CAS No.: 155141-29-0
Purity:  99.73%
Synonyms: BRL 49653C
Target:  

PPAR TRP Channel Autophagy Ferroptosis

Research Areas:  

Metabolic Disease Inflammation/Immunology Cancer

Rosiglitazone maleate (BRL 49653C) is a potent and selective activator of PPARγ, with EC50s of 30 nM, 100 nM and 60 nM for PPARγ1, PPARγ2, and PPARγ, respectively, and a Kd of appr 40 nM for PPARγ; Rosiglitazone maleate is also an modulator of TRP channels, inhibits TRP melastatin 2 (TRPM2), TRPM3 and activates TRP canonical 5 (TRPC5).
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75
Camptothecin
Camptothecin
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75 Cited Publications
Cat. No.: HY-16560
CAS No.: 7689-03-4
Synonyms: Campathecin; (S)-(+)-Camptothecin; CPT
Category:  

Infection Nyssaceae Extract Alkaloids Quinoline Alkaloids 500 - Internal Server Error | MedChemExpress

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