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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
471 Results for "
fats
" in MedChemExpress (MCE) Product Catalog:
Products (471)
471 Results for "fats" in MCE Product Catalog:
34
Category:
Leguminosae/Fabaceae Extract Plant Flavonoids Pueraria edulis Pampan. Extract Phenols Polyphenols Disease Research Fields Cancer Isoflavones
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31 Cited Publications
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Alkaloids Neurological Disease Anti-aging Animal Pyridine Alkaloids Metabolic Disease Disease Research Fields
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31 Cited Publications
Cat. No.: HY-123033B
CAS No.: 2415657-86-0
Category:
Natural Products Neurological Disease Metabolic Disease Endogenous metabolite Disease Research Fields
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31
31 Cited Publications
Category:
Natural Products Neurological Disease Metabolic Disease Endogenous metabolite Disease Research Fields
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21
Category:
Human Gut Microbiota Metabolites Other disease Disease markers Metabolic Disease Microorganism Endogenous metabolite Disease Research Fields Steroids
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21
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17 Cited Publications
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Research Areas:
CTPI-2 is a third-generation mitochondrial citrate carrier SLC25A1 inhibitor with a KD of 3.5 μM. CTPI-2 inhibits glycolysis, PPARγ, and its downstream target the glucose transporter GLUT4. CTPI-2 halts salient alterations of NASH reverting steatosis, preventing the evolution to steatohepatitis, reducing inflammatory macrophage infiltration in the liver and adipose tissue, and starkly mitigating obesity induced by a high-fat diet. Antitumor activity .
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10 Cited Publications
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10,12-Tricosadiynoic acid is a highly specific, selective, high affinity and orally active acyl-CoA oxidase-1 (ACOX1) inhibitor. 10,12-Tricosadiynoic acid can treat high fat diet- or obesity-induced metabolic diseases by improving mitochondrial lipid and ROS metabolism . 10,12-Tricosadiynoic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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9 Cited Publications
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E6446 is a potent and orally acitve TLR7 and TLR9 antagonist, used in the research of deleterious inflammatory responses. E6446 is also a potent SCD1 inhibitor (KD: 4.61 μM), significantly inhibiting adipogenic differentiation and hepatic lipogenesis through SCD1-ATF3 signaling. E6446 also improves liver pathology in high-fat diet (HFD)-fed mice and may be useful in the study of non-alcoholic fatty liver disease (NAFLD) .
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9 Cited Publications
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E6446 dihydrochloride is a potent and orally acitve TLR7 and TLR9 antagonist, used in the research of deleterious inflammatory responses. E6446 dihydrochloride is also a potent SCD1 inhibitor (KD: 4.61 μM), significantly inhibiting adipogenic differentiation and hepatic lipogenesis through SCD1-ATF3 signaling. E6446 dihydrochloride also improves liver pathology in high-fat diet (HFD)-fed mice and may be useful in the study of non-alcoholic fatty liver disease (NAFLD) .
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7 Cited Publications
Cat. No.: HY-W099601
CAS No.: 629-25-4
Synonyms: Lauric acid sodium salt, 99-100%
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6 Cited Publications
Cat. No.: HY-N0324S
CAS No.: 116380-66-6
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
