31

BMS-309403

31 Publications Verification

Cat. No.: HY-101903

CAS No.: 300657-03-8

Purity: 99.93%

Target:

FABP

Research Areas:

Cardiovascular Disease Metabolic Disease

BMS-309403 is a potent, orally active and selective adipocyte fatty acid binding protein (also known as FABP4, aP2) inhibitor with K_is of <2, 250, and 350 nM for FABP4, FABP3, and FABP5, respectively. BMS-309403 interacts with the fatty-acid-binding pocket within the interior of the protein and competitively inhibits the binding of endogenous fatty acids. BMS-309403 improves endothelial function in apolipoprotein E-deficient mice and in cultured human endothelial cells .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

31

BMS-309403 sodium

31 Publications Verification

Cat. No.: HY-101903A

CAS No.: 2802523-05-1

Purity: 99.93%

Target:

FABP

Research Areas:

Cardiovascular Disease Metabolic Disease

BMS-309403 sodium is a potent, orally active, and selective adipocyte fatty acid binding protein (also known as FABP4, aP2) inhibitor, with K_is of <2, 250, and 350 nM for FABP4, FABP3, and FABP5, respectively. BMS-309403 sodium interacts with the fatty-acid-binding pocket within the interior of the protein and competitively inhibits the binding of endogenous fatty acids. BMS-309403 sodium improves endothelial function in apolipoprotein E-deficient mice and in cultured human endothelial cells .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

30

Biotin

30 Cited Publications

Cat. No.: HY-B0511

CAS No.: 58-85-5

Synonyms: Vitamin B7; Vitamin H; D-Biotin

Category:

Microorganisms Immune System Disorder Ketones, Aldehydes, Acids Disease markers Metabolic Disease Plants Other Families Extract Endogenous metabolite Disease Research Fields

Target:

Environmental Pollutants Endogenous Metabolite

Biotin, vitamin B7 and serves as a coenzyme for five carboxylases in humans, involved in the synthesis of fatty acids, isoleucine, and valine, and in gluconeogenesis. Biotin is necessary for cell growth, the production of fatty acids, and the metabolism of fats and amino acids .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

25

NADPH tetrasodium salt

25 Cited Publications

Cat. No.: HY-F0003

CAS No.: 2646-71-1

Target:

Ferroptosis Endogenous Metabolite

Research Areas:

Metabolic Disease Cancer

NADPH tetrasodium salt functions as an important cofactor in a variety of metabolic and biosynthetic pathways. NADPH tetrasodium salt is an endogenous inhibitor of ferroptosis. NADPH tetrasodium salt plays a vital role in the biosynthesis of agents, chiral alcohols, fatty acids and biopolymers, while also being required for lipid biosynthesis, biomass formation, and cell replication .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

25

NADPH tetracyclohexanamine

25 Cited Publications

Cat. No.: HY-F0003A

CAS No.: 100929-71-3

Target:

Ferroptosis Endogenous Metabolite

Research Areas:

Metabolic Disease Cancer

NADPH tetracyclohexanamine functions as an important cofactor in a variety of metabolic and biosynthetic pathways. NADPH tetracyclohexanamine is an endogenous inhibitor of ferroptosis. NADPH tetracyclohexanamine plays a vital role in the biosynthesis of agents, chiral alcohols, fatty acids and biopolymers, while also being required for lipid biosynthesis, biomass formation, and cell replication .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

18

Ruthenium red

18 Cited Publications

Cat. No.: HY-103311

CAS No.: 11103-72-3

Purity: ≥97.0%

Synonyms: Ammoniated ruthenium oxychloride

Target:

Calcium Channel

Research Areas:

Cardiovascular Disease

Ruthenium red (Ammoniated ruthenium oxychloride) is a polycationic dye widely used for electron microscopy (EM) of cells, tissues and vegetative bacteria. Ruthenium red strongly reacts with phospholipids and fatty acids and binds to acidic mucopolysaccharides. Ruthenium red is a L-type calcium current (I_Ca) blocker. When using Ruthenium Red to stain plant tissue sections affected by pathogens, the breakdown of mucilaginous substances by the pathogens prevents them from taking up the stain, whereas the cell walls of healthy tissue stain red .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

7

Sodium dodecanoate, 99-100%

7 Cited Publications

Cat. No.: HY-W099601

CAS No.: 629-25-4

Synonyms: Lauric acid sodium salt, 99-100%

Sodium LaurateIt is an organic compound belonging to fatty acids. It is the sodium salt of lauric acid, a medium-chain saturated fatty acid found in various animal and vegetable fats. Sodium LaurateCommonly used as surfactants, emulsifiers and cleaning agents in various industries such as cosmetics, personal care and detergent industries. It's found in a variety of products, including soaps, shampoos, toothpaste, and laundry detergent. Furthermore, it also has applications in the food industry where it is used as a food additive to improve texture and stability.

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

6

Coenzyme A

6 Cited Publications

Cat. No.: HY-128851

CAS No.: 85-61-0

Purity: 94.29%

Category:

Human Gut Microbiota Metabolites Natural Products Microorganisms Endogenous metabolite

Target:

Endogenous Metabolite Fatty Acid Synthase (FASN)

Coenzyme A (CoASH) is a ubiquitous and essential cofactor, which is an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. Coenzyme A plays a central role in the oxidation of pyruvate in the citric acid cycle and the metabolism of carboxylic acids, including short- and long-chain fatty acids .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

6

Coenzyme A sodium

6 Cited Publications

Cat. No.: HY-128851B

CAS No.: 55672-92-9

Purity: 99.46%

Coenzyme A (CoASH) sodium is a ubiquitous and essential cofactor, which is an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. Coenzyme A plays a central role in the oxidation of pyruvate in the citric acid cycle and the metabolism of carboxylic acids, including short- and long-chain fatty acids .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

6

Coenzyme A trilithium

6 Cited Publications

Cat. No.: HY-128851A

CAS No.: 18439-24-2

Purity: 95.40%

Coenzyme A (CoASH) is a ubiquitous and essential cofactor, which is an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. Coenzyme A plays a central role in the oxidation of pyruvate in the citric acid cycle and the metabolism of carboxylic acids, including short- and long-chain fatty acids .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

5

Intralipid 20%

5 Cited Publications

Cat. No.: HY-131370B

CAS No.: 68890-65-3

Synonyms: 20% Fat Emulsion

Target:

Biochemical Assay Reagents

Research Areas:

Cardiovascular Disease Metabolic Disease Cancer

Intralipid 20% is a safe fat emulsion, composed of soybean oil (consisting of a mixture of long-chain triglycerides (C14-24) of predominantly unsaturated fatty acids), and egg phospholipids, can be used as a nutritional supplement. Intralipid 20% effectively inhibits the opening of the mitochondrial permeability transition pore, effectively protecting the heart from ischaemia-reperfusion injury and has some potential to modulate the innate immune response .

Compare

loading...