Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
166 Results for "
fetal
" in MedChemExpress (MCE) Product Catalog:
Products (166)
166 Results for "fetal" in MCE Product Catalog:
12
12 Publications Verification
UNC0638, a chemical probe, selectively inhibits G9a and GLP histone methyltransferases with IC50 of 15 nM and 19 nM, respectively. UNC0638 inhibits TNBC cell invasion and migration in vitro. UNC0638 is also an inhibitor of EHMT1/2 and induces fetal hemoglobin (HbF) expression in human erythroid progenitor cell culture. In addition, UNC0638 has anti-FMDV (foot-and-mouth disease virus) and anti-VSV (vesicular stomatitis virus) activities, with excellent potency and selectivity against multiple epigenetic and non-epigenetic targets .
11
Target:
Research Areas:
Tolbutamide is an orally active KATP inhibitor. Tolbutamide inhibits cell proliferation, stimulates exocytosis of glucagon and reduces fetal lethality of mice. Tolbutamide can be used in the research of diabete .
11
6
Category:
Target:
6
Target:
Research Areas:
FG-2216 (IOX3) is a potent and orally active inhibitor of HIF prolyl hydroxylase-2 (PHD2), with an IC50 of 3.9 μM. FG-2216 induces robust erythropoietin and modest fetal hemoglobin in vivo .
5
Target:
4
Target:
Research Areas:
Betamethasone is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive activities. Betamethasone accelerates fetal lung maturation and induces gene expression and apoptosis .
4
4 Cited Publications
Synonyms: Boc-Met-Leu-Phe-OH
Target:
Research Areas:
Boc-MLF (Boc-Met-Leu-Phe-OH) is a competitive FPR1 antagonist. Boc-MLF inhibits fMLF-induced neutrophil activation through FPR. Boc-MLF inhibits receptor-induced inflammation and cell migration. Boc-MLF inhibits amniotic epithelial-mesenchymal transition. Boc-MLF reduces pro-inflammatory cytokine levels. Boc-MLF increases collagen expression in fetal membranes. Boc-MLF reverses fetal membrane epithelial cell collapse, increases villi, and reduces mucus attachment. Boc-MLF can be used in research on premature rupture of fetal membranes .
4
Target:
Research Areas:
Boc-MLF TFA (Boc-Met-Leu-Phe-OH TFA) is a competitive FPR1 antagonist. Boc-MLF TFA inhibits fMLF-induced neutrophil activation through FPR. Boc-MLF TFA inhibits receptor-induced inflammation and cell migration. Boc-MLF TFA inhibits amniotic epithelial-mesenchymal transition. Boc-MLF TFA reduces pro-inflammatory cytokine levels. Boc-MLF TFA increases collagen expression in fetal membranes. Boc-MLF TFA reverses fetal membrane epithelial cell collapse, increases villi, and reduces mucus attachment. Boc-MLF TFA can be used in research on premature rupture of fetal membranes .
3
Target:
Research Areas:
2
Target:
Research Areas:
Perfluorodecanoic acid (PFDA) is an orally active perfluoroalkyl substance. Perfluorodecanoic acid causes dysfunction of rat fetal Leydig cells via endoplasmic reticulum stress-mediated changes in lipid components. Perfluorodecanoic acid reduces testosterone biosynthesis in rat R2C Leydig cells by inducing endoplasmic reticulum stress. Perfluorodecanoic acid can be used in studies related to fetal Leydig cell dysfunction .
2
2 Cited Publications
Cat. No.: HY-P81643
Synonyms: KDR; FLK1; VEGFR2; Vascular endothelial growth factor receptor 2; VEGFR-2; fetal liver kinase 1; FLK-1; Kinase insert domain receptor; KDR; Protein-tyrosine kinase receptor flk-1; CD antigen CD309
2
2 Cited Publications
Cat. No.: HY-P70178
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FLT3; CD135 Antigen; Fms Related Receptor Tyrosine Kinase 3; FLK-2; CD135; Growth Factor Receptor Tyrosine Kinase Type III; STK1; Receptor Protein-Tyrosine Kinase; FLK2; Fms-Related Tyrosine Kinase 3; Fms-Like Tyrosine Kinase 3; fetal Liver Kinase 2; Rece
Species:
Human
Source:
HEK293
2
2 Cited Publications
Cat. No.: HY-P81101
Synonyms: COL 3A1; COL3A1; Collagen alpha 1(III) chain; Collagen III alpha 1 chain precursor; Collagen III alpha 1 polypeptide; Collagen type III alpha 1 (Ehlers Danlos syndrome type IV autosomal dominant); Collagen type III alpha 1; Collagen type III alpha; EDS4A; Ehlers Danlos syndrome type IV, autosomal dominant; fetal collagen; Type III collagen; CO3A1_HUMAN; Collagen alpha-1(III) chain; Type III collagen; type III preprocollagen alpha 1 chain.
1
Research Areas:
Chlorothalonil is a broad-spectrum foliar fungicide with oral activity. Chlorothalonil can be used to combat fungal diseases in vegetable and crop leaves. Chlorothalonil can alter the microbial community in the soil. Chlorothalonil inhibits spermatogenesis. Chlorothalonil can cause intestinal epithelial barrier dysfunction and fetal toxicity .
1
1 Cited Publications
Target:
Research Areas:
TN1 is a potent fetal hemoglobin (HbF) inducer.
1
1 Cited Publications
Cat. No.: HY-P70552
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: KDR; fetal Liver Kinase 1; Kinase Insert Domain Receptor; Vascular Endothelial Growth Factor Receptor 2 Variant; Vascular Endothelial Growth Factor Receptor 2; Tyrosine Kinase Growth Factor Receptor; VEGFR2; Receptor Protein-Tyrosine Kinase; FLK1; fetal L
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-W011927S
CAS No.: 2483831-28-1
Synonyms: Bisphenol S (4,4'-Sulfonyldiphenol)-d8
Target:
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
