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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
fibroses
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "fibroses" in MCE Product Catalog:
2
2 Cited Publications
Cat. No.: HY-P71076
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: S100A8; MRP-8; Prev. CAGA; Urinary Stone Protein Band A; Prev. CFAG; Protein S100-A8; MRP8; Calgranulin A; P8; S100 Calcium-Binding Protein A8; Migration Inhibitory Factor-Related Protein 8; Calgranulin-A; Leukocyte L1 Complex Light Chain; CP-10; Calprotectin L1L Subunit; MA387; Cystic Fibrosis Antigen; L1Ag; S100-A8; NIF; 60B8AG; S100 Calcium Binding Protein A8; CGLA; S100A9; 60B8AG; Prev. CAGB; CGLB; Prev. CFAG; MIF; MRP-14; NIF; MRP14; Protein S100-A9; P14; Calgranulin B; Migration Inhibitory Factor-Related Protein 14; S100 Calcium-Binding Protein A9 (Calgranulin B); Leukocyte L1 Complex Heavy Chain; S100 Calcium-Binding Protein A9; Calprotectin L1H Subunit; Calgranulin-B; S100-A9; L1AG; MAC387; S100 Calcium Binding Protein A9; LIAG
Species:
Human
Source:
E. coli
Cat. No.: HY-154979
CAS No.: 2380421-60-1
Target:
Research Areas:
Anti-hepatic fibrosis agent 2 (Compound 6k) is an orally active COL1A1 inhibitor. Anti-hepatic fibrosis agent 2 is an anti-fibrogenic agent targeting ewing sarcoma breakpoint region 1 (EWSR1) .
Cat. No.: HY-L185
2,614 compounds
Fibrosis is a kind of repair response to long-term tissue damage, which is mainly manifested by excessive deposition of extracellular matrix (ECM) and scar formation. Myofibroblasts are the main generating cells of extracellular matrix, and their activation process is related to various pathological mechanisms including Oxidative stress, chronic inflammation and cytokine secretion. Fibrosis can occur in many organs, such as kidneys, liver, heart, lungs, etc. Continuous fibrosis can lead to the destruction of the normal structure of tissues and organs, and if not controlled in time, may cause organ failure or even life-threatening.
MCE contains 2,614 compounds targeting ant-fibrosis targets such as TGF-β, PI3K, Wnt, MMP, etc. These compounds have clear or potential anti-fibrosis activity and can be used for mechanism research and drug screening of fibrosis diseases.
Cat. No.: HY-L125
2,858 compounds
Pulmonary fibrosis (PF), also known as diffuse interstitial pulmonary fibrosis, is a very common end-stage manifestation of several diseases, including idiopathic pulmonary fibrosis (IPF), pulmonary hypertension, and scleroderma, characterised by excessive matrix deposition and destruction of the lung architecture, finally leading to respiratory insufficiency. PF has become a global disease with significantly increased incidence rate, and the most common form of pulmonary fibrosis is idiopathic pulmonary fibrosis (IPF).
Lung fibrosis is a complex disease, a multitude of signal factors and signaling pathways is disrupted in this complex disease, such as TGF-β, Wnt, VEGF and PI3K–Akt. MCE offers a unique collection of 2,858 compounds with identified and potential anti-pulmonary fibrosis activity. MCE Anti-Pulmonary Fibrosis Compound Library is a useful tool for anti-pulmonary fibrosis drugs screening and other related research.
Cat. No.: HY-P703101
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CFTR; MRP7; Prev. ABCC7; ATP-Binding Cassette Sub-Family C Member 7; Prev. CF; Cystic Fibrosis Transmembrane Conductance Regulator ATP-Binding Cassette Sub-Family C Member 7 Mutant; Cystic Fibrosis Transmembrane Conductance Regulator; Cystic Fibrosis Tran
Species:
Human
Source:
HEK293
Cat. No.: HY-P83773
Synonyms: ABC 35 antibody
ABC35 antibody
ABCC 7 antibody
ABCC7 antibody
ATP binding cassette sub family C member 7 antibody;
cAMP dependent chloride channel antibody;
cAMP-dependent chloride channel antibody;
CF antibody;
CFTR antibody;
CFTR/MRP antibody;
CFTR_HUMAN antibody;
Channel conductance controlling ATPase antibody;
Channel conductance-controlling ATPase antibody;
Cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub family C, member 7) antibody;
Cystic fibrosis transmembrane conductance regulator antibody;
Cystic Fibrosis Transmembrane Regulator antibody;
dJ760C5.1 antibody;
MRP 7 antibody;
MRP7 antibody;
TNR CFTR antibody
Cat. No.: HY-P85719
Synonyms: CAGA, CFAG, MRP8, S100A8, Protein S100-A8, Calgranulin-A, Calprotectin L1L subunit, Cystic fibrosis antigen, Leukocyte L1 complex light chain, Migration inhibitory factor-related protein 8, S100 calcium-binding protein A8, Urinary stone protein band A, MRP-8, p8
Cat. No.: HY-P81425
Synonyms: Calgranulin-A antibody;
Calprotectin L1L subunit antibody;
CFAG antibody;
Cystic fibrosis antigen antibody;
Leukocyte L1 complex light chain antibody;
Migration inhibitory factor-related protein 8 antibody;
MRP-8 antibody;
N-terminally processed antibody;
p8 antibody;
Protein S100-A8 antibody;
S100 calcium-binding protein A8 antibody;
S100A8 antibody;
S10A8_HUMAN antibody;
Urinary stone protein band A antibody
Cat. No.: HY-P76586
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: S100A8; MRP-8; Prev. CAGA; Urinary Stone Protein Band A; Prev. CFAG; Protein S100-A8; MRP8; Calgranulin A; P8; S100 Calcium-Binding Protein A8; Migration Inhibitory Factor-Related Protein 8; Calgranulin-A; Leukocyte L1 Complex Light Chain; CP-10; Calprotectin L1L Subunit; MA387; Cystic Fibrosis Antigen; L1Ag; S100-A8; NIF; 60B8AG; S100 Calcium Binding Protein A8; CGLA
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P83734
Synonyms: Leukocyte L1 complex heavy chain antibody; 60B8AG antibody; CAGB antibody; Calgranulin B antibody; Calgranulin-B antibody; Calprotectin L1H subunit antibody; CFAG antibody; CGLB antibody; Cystic fibrosis antigen B antibody; L1AG antibody;
Leukocyte L1 complex heavy chain antibody; LIAG antibody; MAC387 antibody; MIF antibody; Migration inhibitory factor related protein 14 antibody; Migration inhibitory factor-related protein 14 antibody; MRP 14 antibody; MRP-14 antibody; MRP14 antibody; Myeloid-related protein 14 antibody; NIF antibody; OTTHUMP00000015331 antibody; p14 antibody; Protein S100-A9 antibody; S100 A9 antibody; S100 calcium binding protein A9 antibody; S100 calcium binding protein A9 calgranulin B antibody;
S100 calcium-binding protein A9 antibody; S100A9 antibody; S10A9_HUMAN antibody;
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
