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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
54 Results for "
flavin reductase
" in MedChemExpress (MCE) Product Catalog:
Products (54)
54 Results for "flavin reductase" in MCE Product Catalog:
12
11
Category:
Cardiovascular Disease Human Gut Microbiota Metabolites Natural Products Microorganisms Plants Other Families Extract Endogenous metabolite Disease Research Fields
Target:
11
Target:
7
7 Cited Publications
Synonyms: MitoParaquat
Target:
Research Areas:
MitoPQ is a mitochondria-targeted redox cycler. MitoPQ produces superoxide by redox cycling at the flavin site of complex I, selectively increasing superoxide production within mitochondria. MitoPQ can be used in antioxidant study .
2
2 Cited Publications
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Research Areas:
TAK-418 is an orally active, blood-brain barrier-penetrant LSD1 inhibitor with a human IC50 of 2.9 nM. TAK-418 irreversibly inhibits LSD1 by forming a compact flavin-FAD adduct with the catalytic domain FAD, blocking the demethylation of H3K4me1/2 and H3K9me1/2 without disrupting the LSD1-GFI1B interaction. TAK-418 restores normally dysregulated brain gene expression and DNA methylation, increases H3K4me1/2/3 and H3K9me2 at the Ucp2 locus, and induces Ucp2 mRNA expression. TAK-418 rescues defective H3K4 histone modifications, normalizes adult neurogenesis, and improves recognition memory, social behavior, and cognition in rodent models. TAK-418 can be used in research related to neurodevelopmental disorders, Alzheimer's disease, and autism spectrum disorders .
1
1 Cited Publications
Synonyms: Vitamin B2 (Standard); E101 (Standard)
1
1 Cited Publications
Cat. No.: HY-P71709
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: FRZB; FZRB; Frizzled Related Protein; HFIZ; Secreted Frizzled-Related Protein 3; Frezzled; FRZB1; SFRP-3; SFRP3; FrzB-1; FRE; Uncharacterized Protein FRZB; Frizzled-Related Protein 1; Frizzled Homolog-Related; FRZB-PEN; Frizzled-Related Protein; FRZB-1; F
Species:
E.coli
Source:
E. coli
Roseoflavin, a natural pigment originally isolated from Streptomyces davawensis, is an antimetabolite analog of Riboflavin and flavin mononucleotide that has antimicrobial properties .
Target:
Research Areas:
Riboflavin Tetrabutyrate is a lipophilic flavin derivative with antioxidative and lipid peroxide-removing activity.
Cat. No.: HY-B1654S
Synonyms: FAD-13C5 ammonium
Cat. No.: HY-W009247
CAS No.: 161696-76-0
Synonyms: N-Demethylolanzapine; LY170055
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Research Areas:
N-Desmethylolanzapine is an antipsychotic drug.
The formation of N-Desmethylolanzapine correlates with the level and activity
of human liver flavin-containing monooxygenase (FMO3). N-Desmethylolanzapine
can be used in the study of antipsychotic drugs .
Cat. No.: HY-N11425
CAS No.: 36504-71-9
Category:
Target:
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Riboflavin Tetrabutyrate (Standard) is the analytical standard of Riboflavin Tetrabutyrate. This product is intended for research and analytical applications. Riboflavin Tetrabutyrate is a lipophilic flavin derivative with antioxidative and lipid peroxide-removing activity.
Cat. No.: HY-175593
CAS No.: 696628-90-7
Research Areas:
M6766 is a selective endoplasmic reticulum oxidoreductase 1α (ERO1α) inhibitor with an IC50 of 1.4 μM and a KD of 1.1 μM. M6766 also inhibits ERO1β with an IC50 of 7.2 μM. M6766 binds to the flavin adenine dinucleotide-binding pocket in ERO1α. M6766 inhibits granule secretion, αIIbβ3 integrin activation, Ca 2+ mobilization, and platelet aggregation. M6766 can be used for the research of neurological disease, such as ischemic stroke .
Cat. No.: HY-B0456S5
Synonyms: Vitamin B2-d8 ; E101-d8
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Research Areas:
Diaphorase, Clostridium sp. is a diaphorase derived from Clostridium sp. As a flavin-containing NAD (P) H dehydrogenase, Diaphorase, Clostridium sp. uses NADH as an electron donor to reduce artificial dyes such as DCPIP and NBT, and participates in energy metabolism .
Cat. No.: HY-144169
CAS No.: 2742675-85-8
Research Areas:
DHODH-IN-19 is a potent inhibitor of DHODH. DHODH is present in the inner membrane of human mitochondria and is an iron-containing flavin-dependent enzyme. DHODH-IN-19 inhibits tumor growth. DHODH-IN-19 has the potential for the research of cancer and inflammation disease (extracted from patent WO2021238881A1, compound 1) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
