216 Results for "

fructose

" in MedChemExpress (MCE) Product Catalog:
Products (216)

216 Results for "fructose" in MCE Product Catalog:

5
5 Cited Publications
Cat. No.: HY-N0395
CAS No.: 7660-25-5
Synonyms: beta-D-Fructopyranose
Fructose is a simple ketonic monosaccharide found in many plants, where it is often bonded to glucose to form the disaccharide sucrose.
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12
12 Publications Verification
Cat. No.: HY-B1779
CAS No.: 57-50-1
Synonyms: D-(+)-Saccharose
Sucrose (D-(+)-Saccharose) is a disaccharide which is composed of two monosaccharides, glucose and fructose. Sucrose can be applied in some animal models, including metabolic disease, obesity, diet on preference, and diabetes, et al .
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7
7 Cited Publications
Cat. No.: HY-16307
CAS No.: 261365-11-1
Target:  

FBPase

Research Areas:  

Metabolic Disease Cancer

MB05032 is a fructose-1,6-bisphosphatase (FBP1/FBPase) inhibitor with an IC50 value of 16 nM. MB05032 blocks FBP1-mediated glycolysis inhibition in NK cells, restores NK cell glucose uptake, lactate production, degranulation, perforin production, and cytotoxicity against gastric cancer cells. MB05032 elevates ATP/ADP ratios, increases glucose utilization, and enhances insulin secretion in pancreatic β-cells. MB05032 increases neutrophil adhesion, phagocytosis, and mRNA abundance of HKII, ITGA9, CD36 in subclinically hypocalcemic dairy cows. MB05032 inhibits gluconeogenesis in hepatocytes, acts as the active metabolite of prodrug Managlinat dialanetil (MB06322) (HY-14955). MB05032 can be used for the research of gastric cancer, type 2 diabetes, subclinical hypocalcemia, and insulin resistance .
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4
4 Cited Publications
Cat. No.: HY-123981
CAS No.: 47208-82-2
Purity:  99.72%
Target:  

Phosphatase

Research Areas:  

Cancer

5MPN is a first-in-class, potent, orally active and selective 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (PFKFB4) inhibitor. 5MPN appears to be a competitive inhibitor of the F6P binding site (Ki=8.6 μM). 5MPN does not inhibit PFK-1 or PFKFB3. 5MPN targets the sugar metabolism of tumors and suppresses proliferation of multiple human cancer cell lines .
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3
3 Cited Publications
Cat. No.: HY-N0761
CAS No.: 537-73-5
Synonyms: 3-Hydroxy-4-methoxycinnamic acid
Isoferulic acid (3-Hydroxy-4-methoxycinnamic acid) is an orally active cinnamic acid derivative. Isoferulic acid exhibits hypoglycemic, antiviral, and antioxidant activities. Isoferulic acid can also inhibit fructose- and glucose-mediated protein glycation. Isoferulic acid can be used in the research of diseases such as diabetes .
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2
2 Cited Publications
Cat. No.: HY-P70275
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FBP1; Liver FBPase; Prev. FBP; Growth-Inhibiting Protein 17; fructose-1,6-Bisphosphatase 1; fructose-Bisphosphatase; D-fructose-1,6-Bisphosphate 1-Phosphohydrolase 1; fructose-Bisphosphatase 1; FBPase 1
Species:  
Human
Source:  
HEK293
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2
2 Cited Publications
Cat. No.: HY-W179181
CAS No.: 852702-51-3
Target:  

GLUT

Research Areas:  

Metabolic Disease Cancer

MSNBA is a potent and selective GLUT5 fructose transport inhibitor with an IC50 of 0.10 mM. MSNBA does not affect the transport activity of human GLUT1, GLUT2, GLUT3, GLUT4 or bacterial GlcPSe. MSNBA competitively inhibits GLUT5 fructose uptake with a Ki of 3.2 μM in MCF7 cells. MSNBA can be used for the study of cancer or diabetes .
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2
2 Cited Publications
Cat. No.: HY-N0668
CAS No.: 64849-39-4
Rubusoside is a diterpene glycoside that is also a sweetener and solubilizer with anti-angiogenic, anti-cancer, anti-obesity, anti-allergic and anti-asthmatic effects. Rubusoside attenuates airway hyperresponsiveness and reduces inflammatory cells in bronchoalveolar lavage fluid (BALF), reducing OVA (HY-W250978)-induced airway inflammation. Rubusoside also prevents palmitic acid-induced lipotoxicity in pancreatic INS-1 cells, reduces the transport of human glucose transporters GLUT-1 and fructose GLUT-5, and inhibits NF-κB and α-amylase (α-amylase) .
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1
1 Cited Publications
Cat. No.: HY-N7092
CAS No.: 57-48-7
Synonyms: D(-​)​-​fructose
Category:  

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