142 Results for "

genotoxicity

" in MedChemExpress (MCE) Product Catalog:
Products (142)

142 Results for "genotoxicity" in MCE Product Catalog:

4
Benzamidine
Benzamidine
0 Images
4 Cited Publications
Cat. No.: HY-125913
CAS No.: 618-39-3
Target:  

Ser/Thr Protease

Research Areas:  

Inflammation/Immunology

Benzamidine is a competitive protease inhibitor that blocks the hydrolytic cleavage of glucagon by plasmin, trypsin and thrombin. Benzamidine effectively inhibits the degradation of glucagon by relevant proteases during the collection, storage and analysis of human plasma and blood samples. During in vivo metabolism, Benzamidine undergoes N-hydroxylation and produces multiple metabolites, exhibiting characteristics of delayed excretion or biphasic elimination. Benzamidine only induces slight single-strand DNA breaks at high concentrations and shows no significant genotoxic potential overall. Benzamidine may interfere with the detection of some glucagon antisera, but does not affect key antigen-antibody affinity at specific concentrations. Benzamidine can be used as a stabilizer in glucagon radioimmunoassays to ensure the accuracy and recovery rate of detection results .
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4
Benzamidine hydrochloride
Benzamidine hydrochloride
0 Images
4 Cited Publications
Cat. No.: HY-W018781
CAS No.: 1670-14-0
Target:  

Ser/Thr Protease

Research Areas:  

Cancer

Benzamidine hydrochloride is a competitive protease inhibitor that blocks the hydrolytic cleavage of glucagon by plasmin, trypsin and thrombin. Benzamidine hydrochloride effectively inhibits the degradation of glucagon by relevant proteases during the collection, storage and analysis of human plasma and blood samples. During in vivo metabolism, Benzamidine hydrochloride undergoes N-hydroxylation and produces multiple metabolites, exhibiting characteristics of delayed excretion or biphasic elimination. Benzamidine hydrochloride only induces slight single-strand DNA breaks at high concentrations and shows no significant genotoxic potential overall. Benzamidine hydrochloride may interfere with the detection of some glucagon antisera, but does not affect key antigen-antibody affinity at specific concentrations. Benzamidine hydrochloride can be used as a stabilizer in glucagon radioimmunoassays to ensure the accuracy and recovery rate of detection results .
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4
Skimmianine
Skimmianine
0 Images
4 Cited Publications
Cat. No.: HY-N2081
CAS No.: 83-95-4
Category:  

Rutaceae Extract Alkaloids Quinoline Alkaloids Plants 500 - Internal Server Error | MedChemExpress

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