35 Results for "

geranylgeranyl

" in MedChemExpress (MCE) Product Catalog:
Products (35)

35 Results for "geranylgeranyl" in MCE Product Catalog:

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1
Farnesyl pyrophosphate ammonium
Farnesyl pyrophosphate ammonium
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1 Cited Publications
Cat. No.: HY-113037C
CAS No.: 116057-57-9
Purity:  ≥95.0%
Synonyms: Farnesyl diphosphate ammonium
Category:  

Natural Products Neurological Disease Endogenous metabolite Disease Research Fields

Target:  

TRP Channel Endogenous Metabolite Calcium Channel

Farnesyl pyrophosphate (Farnesyl diphosphate) ammonium is a metabolic intermediate in the mevalonate (MVA) pathway. It is a TRP channel (TRPM2) agonist that triggers Ca2+ influx and cell death. Farnesyl pyrophosphate ammonium is a key branch substrate for cholesterol synthesis, ubiquinone synthesis, protein farnesylation, and geranylgeranyl pyrophosphate (GGPP) synthesis. Farnesyl pyrophosphate ammonium is used in research on cerebral ischemia, neurodegenerative diseases, pancreatic cancer, inflammation, and autoimmune diseases .
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FGTI-2734
FGTI-2734
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1 Cited Publications
Cat. No.: HY-128350
CAS No.: 1247018-19-4
Purity:  99.85%
Target:  

Farnesyl Transferase

Research Areas:  

Cancer

FGTI-2734 is a RAS C-terminal mimetic dual farnesyl transferase (FT) and geranylgeranyl transferase-1 (GGT-1) inhibitor with IC50s of 250 nM and 520 nM for FT and GGT-1, respectively. FGTI-2734 can prevent membrane localization of KRAS, hence solving KRAS resistance problem and thwarting mutant KRAS patient-derived pancreatic tumors .
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FGTI-2734 mesylate
FGTI-2734 mesylate
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1 Cited Publications
Cat. No.: HY-128350A
CAS No.: 2702297-24-1
Purity:  99.65%
Target:  

Farnesyl Transferase γ-Glutamyl Transferase (GGT)

Research Areas:  

Cancer

FGTI-2734 mesylate is a RAS C-terminal mimetic dual farnesyl transferase (FT) and geranylgeranyl transferase-1 (GGT) inhibitor with IC50s of 250 nM and 520 nM for FT and GGT, respectively. FGTI-2734 mesylate can prevent membrane localization of KRAS, hence solving KRAS resistance problem and thwarting mutant KRAS patient-derived pancreatic tumors .
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Geranylgeranyl pyrophosphate triammonium
Geranylgeranyl pyrophosphate triammonium
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Cat. No.: HY-126370A
CAS No.: 313263-08-0
Purity:  ≥95.0%
Category:  

Natural Products Endogenous metabolite Disease Research Fields Cancer

Target:  

Endogenous Metabolite YAP Apoptosis Interleukin Related STAT ERK Ras

Geranylgeranyl pyrophosphate triammonium is a type of isoprenoid metabolic intermediate, mainly synthesized through the mevalonate pathway. Geranylgeranyl pyrophosphate triammonium is a key precursor in various biological synthesis processes, especially as a necessary substrate for post-translational modification of proteins - geranylgeranyl phosphorylation. Geranylgeranyl pyrophosphate triammonium regulates various cellular processes and disease progression through protein geranylgeranyl phosphorylation, such as activating the YAP signaling pathway, promoting cell proliferation and inhibiting apoptosis; promoting IL-2 production and STAT5 phosphorylation; and influencing metabolic homeostasis and cancer, etc .
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Geranylgeranyl pyrophosphate
Geranylgeranyl pyrophosphate
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Cat. No.: HY-126370
CAS No.: 6699-20-3
Category:  

Human Gut Microbiota Metabolites Natural Products Endogenous metabolite Disease Research Fields Cancer

Target:  

Endogenous Metabolite YAP Apoptosis Interleukin Related STAT ERK Ras

Geranylgeranyl pyrophosphate is a type of isoprenoid metabolic intermediate, mainly synthesized through the mevalonate pathway. Geranylgeranyl pyrophosphate is a key precursor in various biological synthesis processes, especially as a necessary substrate for post-translational modification of proteins - geranylgeranyl phosphorylation. Geranylgeranyl pyrophosphate regulates various cellular processes and disease progression through protein geranylgeranyl phosphorylation, such as activating the YAP signaling pathway, promoting cell proliferation and inhibiting apoptosis; promoting IL-2 production and STAT5 phosphorylation; and influencing metabolic homeostasis and cancer, etc .
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(E/Z)-Farnesyl pyrophosphate
(E/Z)-Farnesyl pyrophosphate
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Cat. No.: HY-113037
CAS No.: 13058-04-3
Synonyms: (E/Z)-Farnesyl diphosphate
Category:  

Human Gut Microbiota Metabolites Natural Products Microorganisms Neurological Disease Endogenous metabolite Disease Research Fields

Target:  

TRP Channel Endogenous Metabolite

(E/Z)-Farnesyl pyrophosphate ((E/Z)-Farnesyl diphosphate), a 15-carbon isoprenoid, is a metabolic intermediate of the mevalonate (MVA) pathway. (E/Z)-Farnesyl pyrophosphate is a TRPM2 (TRP Channel) agonist, activates TRPM2 opening for ion influx. (E/Z)-Farnesyl pyrophosphate is a key branch substrate for cholesterol synthesis, ubiquinones synthesis, protein farnesylation decoration, and geranyl-geranyl pyrophosphate (GGPP) synthesis .
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(S)-(-)-Perillyl alcohol
(S)-(-)-Perillyl alcohol
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Cat. No.: HY-116514
CAS No.: 18457-55-1
Purity:  ≥98.0%
Category:  

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