14

14 Publications Verification

Target:

Research Areas:

Infection Neurological Disease Inflammation/Immunology Cancer

Allopurinol is a potent and orally active xanthine oxidase inhibitor with an IC₅₀ value of 0.2-50 μM. Allopurinol can be used in the research of hyperuricemia and gout. Allopurinol decreases the expression of HIF-1α and HIF-2α protein. Allopurinol shows anti-depressant and anti-nociception activity. Anti-leishmanial effect .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

14

Allopurinol sodium

14 Publications Verification

Cat. No.: HY-B0219A

CAS No.: 17795-21-0

Target:

Xanthine Oxidase

Research Areas:

Infection Neurological Disease Inflammation/Immunology Cancer

Allopurinol sodium is a potent and orally active xanthine oxidase inhibitor with an IC₅₀ value of 0.2-50 μM. Allopurinol sodium can be used in the research of hyperuricemia and gout. Allopurinol sodium decreases the expression of HIF-1α and HIF-2α protein. Allopurinol sodium shows anti-depressant and anti-nociception activity. Anti-leishmanial effect .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

13

Febuxostat

13 Cited Publications

Cat. No.: HY-14268

CAS No.: 144060-53-7

Purity: 99.94%

Synonyms: TEI 6720; TMX 67

Target:

Xanthine Oxidase

Research Areas:

Cardiovascular Disease Metabolic Disease Cancer

Febuxostat (TEI 6720) is a potent, selective and non-purine xanthine oxidase (XO) inhibitor with a K_i value of 0.6 nM. Febuxostat has the potential for the research of hyperuricemia and gout .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

11

Benzbromarone

11 Cited Publications

Cat. No.: HY-B1135

CAS No.: 3562-84-3

Target:

Xanthine Oxidase Apoptosis Interleukin Related Keap1-Nrf2 SOD Caspase Bcl-2 Family NF-κB JNK HSP

Research Areas:

Metabolic Disease

Benzbromarone is an orally active anti-gout agent. Benzbromarone has anti-infammatory, anti-oxidative stress and nephroprotective effects. Benzbromarone can be used for the research of hyperuricemia and gout .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

3

Imidazole

3 Cited Publications

Cat. No.: HY-D0837

CAS No.: 288-32-4

Synonyms: Glyoxaline; 1,3-Diaza-2,4-cyclopentadiene

Imidazole (Glyoxaline; 1,3-Diaza-2,4-cyclopentadiene) is a heterocyclic aromatic compound. Imidazole bearing molecules have been used as corrosion, acetylcholinesterase (AChEI) and xanthine oxidase (XO) inhibitors, performing biological activities such as antifungal, antituberculosis, anti-inflammatory, antioxidant, and analgesic, amongst many others. Imidazole inhibits the enzymatic conversion of the endoperoxides (PGG₂ and PGH₂) to thromboxane A2 by platelet microsomes. Imidazole derivatives exhibits inhibition on SARS-CoV-2 3CL ^Pro enzyme, which is promising for research in the field of Alzheimer’s disease, gout, COVID-19 and thrombo-embolic disease .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

3

LT052

3 Cited Publications

Cat. No.: HY-130622

CAS No.: 2543545-44-2

Purity: 98.77%

Target:

Epigenetic Reader Domain

Research Areas:

Inflammation/Immunology

LT052 is a highly selective BET BD1 inhibitor with an IC₅₀ of 87.7 nM. LT052 exhibits nanomolar BRD4 BD1 potency and 138-fold selectivity over BRD4 BD2 (IC₅₀=12.130 μM). LT052 has anti-inflammatory?activity and can be used for acute gout arthritis research .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

2

(Z)-Aconitic acid

2 Cited Publications

Cat. No.: HY-W016814

CAS No.: 585-84-2

Synonyms: cis-Aconitic acid

Category:

Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Other Diseases Endogenous metabolite Disease Research Fields

Target:

Endogenous Metabolite Amino Acid Decarboxylase

(Z)-Aconitic acid is an orally active glutamate decarboxylase inhibitor. (Z)-Aconitic acid reduces IκB-α phosphorylation. (Z)-Aconitic acid inhibits Antigen-induced arthritis and Monosodium urate (HY-B2130A)-induced gout .

Compare

loading...