2 Results for "

hBMECs

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "hBMECs" in MCE Product Catalog:

AM9928
AM9928
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Cat. No.: HY-182639
CAS No.: 1869033-49-7
Target:  

Exosomes MAGL Interleukin Related VEGFR

Research Areas:  

Cancer

AM9928 is a monoacylglycerol lipase (MAGL) inhibitor with IC50 and Ki values of 8.9 nM and 7.3 nM, respectively. AM9928 blocks the adhesion and migration of triple-negative breast cancer (TNBC) cells, and inhibits the secretion of IL-6, IL-8 and VEGF-A by TNBC cells. AM9928 suppresses the activation of human brain microvascular endothelial cells (HBMECs) induced by TNBC-derived exosomes, and reduces the secretion of IL-8 and VEGF-A by HBMECs. AM9928 attenuates changes in blood-brain barrier permeability, inhibits tumor growth in the mammary fat pad, and reduces brain colonization of TNBC. AM9928 can be used in studies related to triple-negative breast cancer .
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11β,13-Dihydrolactucopicrin
11β,13-Dihydrolactucopicrin
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Cat. No.: HY-N9932
CAS No.: 125519-47-3
Category:  

Terpenoids Sesquiterpenes Plants 500 - Internal Server Error | MedChemExpress

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