40 Results for "

heptapeptide

" in MedChemExpress (MCE) Product Catalog:
Products (40)

40 Results for "heptapeptide" in MCE Product Catalog:

19
19 Publications Verification
Cat. No.: HY-12403
CAS No.: 51833-78-4
Purity:  99.75%
Synonyms: TXA127; Angiotensin (1-7); Ang-(1-7)
Angiotensin 1-7 (Ang-(1-7)) is an endogenous heptapeptide from the renin-angiotensin system (RAS) with a cardioprotective role due to its anti-inflammatory and anti-fibrotic activities in cardiac cells. Angiotensin 1-7 inhibits purified canine ACE activity (IC50=0.65 μM). Angiotensin 1-7 acts as a local synergistic modulator of kinin-induced vasodilation by inhibiting ACE and releasing nitric oxide. Angiotensin 1-7 blocks Ang II-induced smooth muscle cell proliferation and hypertrophy and shows antiangiogenic and growth-inhibitory effects on the endothelium. Angiotensin 1-7 shows anti-inflammatory activity .
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19
19 Publications Verification
Cat. No.: HY-12403A
CAS No.: 2855063-75-9
Purity:  99.87%
Synonyms: TXA127 acetate; Angiotensin (1-7) acetate; Ang-(1-7) acetate
Angiotensin 1-7 (Ang-(1-7)) acetate is an endogenous heptapeptide from the renin-angiotensin system (RAS) with a cardioprotective role due to its anti-inflammatory and anti-fibrotic activities in cardiac cells. Angiotensin 1-7 acetate inhibits purified canine ACE activity (IC50=0.65 μM). Angiotensin 1-7 acetate acts as a local synergistic modulator of kinin-induced vasodilation by inhibiting ACE and releasing nitric oxide. Angiotensin 1-7 acetate blocks Ang II-induced smooth muscle cell proliferation and hypertrophy and shows antiangiogenic and growth-inhibitory effects on the endothelium .
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9
9 Cited Publications
Cat. No.: HY-B0686
CAS No.: 188627-80-7
Target:  

Integrin

Research Areas:  

Cardiovascular Disease

Eptifibatide is a cyclic heptapeptide, acts as a competitive antagonist for the activated platelet glycoprotein IIb/IIIa receptor, with anti-platelet activity .
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9
9 Cited Publications
Cat. No.: HY-B0686B
CAS No.: 881997-86-0
Target:  

Integrin

Research Areas:  

Cardiovascular Disease

Eptifibatide acetate is a cyclic heptapeptide, acts as a competitive antagonist for the activated platelet glycoprotein IIb/IIIa receptor, with anti-platelet activity .
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2
2 Cited Publications
Cat. No.: HY-P10368
CAS No.: 1411976-18-5
P110 heptapeptide is a peptide inhibitor of the Drp1-Fis1 interaction. P110 heptapeptide has anti-inflammatory, immunomodulatory, mitochondrial protective, and neuroprotective activities. Without blocking the physiological functions of Drp1, P110 heptapeptide reduces pathological functions in many models of neurodegeneration, ischemia, and sepsis. P110 heptapeptide can be used for research on neurological and inflammatory diseases .
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2
2 Cited Publications
Cat. No.: HY-P0248
CAS No.: 65189-71-1
Target:  

PKA

Research Areas:  

Metabolic Disease

Kemptide is a synthetic heptapeptide that acts as a specific substrate for cAMP-dependent protein kinase (PKA).
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2
2 Cited Publications
Cat. No.: HY-P1663A
ATWLPPR Peptide TFA, a heptapeptide, acts as a selective neuropilin-1 inhibitor, inhibits VEGF165 binding to NRP-1, used in the research of angiogenesis . ATWLPPR Peptide TFA has potential in reducing the early retinal damage caused by diabetes .
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2
2 Cited Publications
Cat. No.: HY-P1663
CAS No.: 272121-15-0
Target:  

VEGFR

Research Areas:  

Others

ATWLPPR Peptide is a biological active peptide. (This peptide is a specific VEGFR2/KDR heptapeptide antagonist, it binds VEGFR2 (KDR/flk), completely inhibiting VEGF binding to KDR and preventing VEGF-induced angiogenesis in-vivo. It specifically inhibits human endothelial cell proliferation in-vitro and totally abolishes VEGF-induced angiogenesis in-vivo.)
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1
1 Cited Publications
Cat. No.: HY-P0244
CAS No.: 77614-16-5
Dermorphin is a natural heptapeptide μ-opioid receptor (MOR) agonist found in amphibian skin. Inhibition of neuropathic pain .
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1
1 Cited Publications
Cat. No.: HY-P2031
CAS No.: 26645-35-2
Phallacidin is a natural bicyclic heptapeptide derived from the poisonous mushroom Amanita phalloides. Phallacidin binds to filamentous actin specifically with high affinity, with a Kd of 20 nM. After binding to F-actin, Phallacidin strongly inhibits its depolymerization, stabilizes microfilament structures, and prevents their disruption by drugs such as cytochalasins. When conjugated with a fluorophore, Phallacidin serves as a specific fluorescent probe for F-actin, which is used to clearly visualize the distribution of actin in the cytoskeleton (e.g., stress fibers, cortical peripheral bands) under fluorescence microscopy .
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Cat. No.: HY-P10940
CAS No.: 845727-63-1
Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

Ac-RFAAKAA-COOH is a heptapeptide with one reactive Lys residue. Ac-RFAAKAA-COOH forms stable covalent adducts with isothiocyanates, resulting in peptide depletion over time. Ac-RFAAKAA-COOH acts as a model peptide in direct peptide reactivity assays, where its chemical reactivity is evaluated via fluorescamine-based free amine assays. Ac-RFAAKAA-COOH can be used in studies related to allergic contact dermatitis and skin sensitization .
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Cat. No.: HY-P1540
CAS No.: 13602-53-4
Angiotensin III, human, mouse is a heptapeptide, acts as an endogenous angiotensin type 2 receptor (AT2R) agonist, with IC50s of 0.648 nM and 21.1 nM for AT2R and AT1R, respectively.
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Cat. No.: HY-P10940A
Target:  

Inhibitory Antibodies

Research Areas:  

Others

Ac-RFAAKAA-COOH TFA is a heptapeptide with one reactive Lys residue. Ac-RFAAKAA-COOH TFA can be used for detecting skin sensitizing components in cosmetics and other substances .
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Cat. No.: HY-P3675
CAS No.: 51776-33-1
Target:  

GnRH Receptor

Research Areas:  

Endocrinology

LH-RH (4-10) is a heptapeptide, one of major degradation products of luteinising-hormone releasing hormone (LHRH) via pituitary and hypothalamus. LH-RH (4-10) produced in macrophages and type II pneumocytes .
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Cat. No.: HY-P3890A
Target:  

Neurokinin Receptor

Research Areas:  

Neurological Disease

Substance P (5-11) TFA TFA, the C-terminal heptapeptide of Substance P (HY-P0201), is a neuropeptide. Substance P (5-11) TFA TFA binds to NK-1 tachykinin receptor .
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Cat. No.: HY-125357
CAS No.: 148619-41-4
Target:  

Inhibitory Antibodies

Research Areas:  

Metabolic Disease

Ternatin (compound 2) is a cyclic heptapeptides that can be isolated from mushroom Coliorus versicolor. Ternatin inhibits fat-accumulation with an IC50 of 0.027 μM in 3T3-L1 adipocytes .
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Cat. No.: HY-P5219
CAS No.: 1459206-66-6
Target:  

Inhibitory Antibodies

Research Areas:  

Others

Acetyl heptapeptide-4 is a bioactive peptide with antiallergic effect and has been reported used as a cosmetic ingredient .
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Cat. No.: HY-P2627
CAS No.: 47910-79-2
Research Areas:  

Others

CCK (27-33) is the C-terminal heptapeptide of cholecystokinin (CCK) .
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Cat. No.: HY-P4196
CAS No.: 73024-95-0
Met-Enkephalin-Arg-Phe is a naturally occurring heptapeptide with analgesic activity .
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Cat. No.: HY-B0686A
CAS No.: 1248559-53-6
Target:  

Integrin

Research Areas:  

Cardiovascular Disease

Eptifibatide monoacetate is a cyclic heptapeptide, acts as a competitive antagonist for the activated platelet glycoprotein IIb/IIIa receptor, with anti-platelet activity .
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