85 Results for "

herbal matrices

" in MedChemExpress (MCE) Product Catalog:
Products (85)

85 Results for "herbal matrices" in MCE Product Catalog:

83
83 Cited Publications
Cat. No.: HY-N0716B
CAS No.: 633-66-9
Synonyms: Natural Yellow 18 sulfate
Berberine sulfate is an alkaloid isolated from the Chinese herbal medicine Huanglian, as an antibiotic. Berberine sulfate induces reactive oxygen species (ROS) generation and inhibits DNA topoisomerase. Berberine sulfate has antineoplastic properties. The sulfate form improves bioavailability .
loading...
    loading...
76
76 Cited Publications
Cat. No.: HY-N0822
CAS No.: 517-89-5
Synonyms: C.I. 75535; Isoarnebin 4
Shikonin is a major component of a Chinese herbal medicine named zicao. Shikonin is a potent TMEM16A chloride channel inhibitor with an IC50 of 6.5 μM . Shikonin is a specific pyruvate kinase M2 (PKM2) inhibitor and can also inhibit TNF-α and NF-κB pathway . Shikonin decreases exosome secretion through the inhibition of glycolysis . Shikonin inhibits AIM2 inflammasome activation .
loading...
    loading...
55
55 Cited Publications
Cat. No.: HY-N0716A
CAS No.: 316-41-6
Synonyms: Natural Yellow 18 hemisulfate
Berberine hemisulfate is the hemisulfate form of Berberine (HY-N0716). Berberine hemisulfate is an alkaloid isolated from the Chinese herbal medicine Huanglian. Berberine hemisulfate exhibits anti-inflammatory, antibiobic, antitumor, cardiovascular protective and neuroprotective activity .
loading...
    loading...
25
25 Cited Publications
Cat. No.: HY-N0289
CAS No.: 2188-68-3
Lycorine hydrochloride is the main active ingredient of the herbal medicine derived from Lycoris radiata (L’Her.) Herb. and is also a melanoma vasculogenic inhibitor and has anti-tumor activity . Lycorine hydrochloride effectively inhibits mitotic proliferation of Hey1B cells (IC50 of 1.2 μM) .
loading...
    loading...
20
20 Cited Publications
Cat. No.: HY-N0115
CAS No.: 62499-27-8
Synonyms: Gastrodine
Gastrodin, a main constituent of a Chinese herbal medicine Tianma, has been known to display anti-inflammatory effects. Gastrodin inhibits ethanol-induced hepatocellular apoptosis. Gastrodin inhibits H2O2-induced ferroptosis through its antioxidative effect. Gastrodin can be used for study of dizziness, epilepsy, stroke and dementia .
loading...
    loading...
12
12 Cited Publications
Cat. No.: HY-N0510
CAS No.: 313-67-7
Synonyms: Aristolochic acid I; TR 1736
Aristolochic acid A (Aristolochic acid I; TR 1736) is the main component of plant extract Aristolochic acids, which are found in various herbal plants of genus Aristolochia and Asarum. Aristolochic acid A significantly reduces both activator protein 1 (AP-1) and NF-κB activities. Aristolochic acid A reduces BLCAP gene expression in human cell lines .
loading...
    loading...
12
12 Cited Publications
Cat. No.: HY-N0510A
CAS No.: 10190-99-5
Synonyms: Aristolochic acid I sodium; TR 1736 sodium
Aristolochic acid A (Aristolochic acid I) sodium is the main component of plant extract Aristolochic acids, which are found in various herbal plants of genus Aristolochia and Asarum. Aristolochic acid A sodium significantly reduces both activator protein 1 (AP-1) and NF-κB activities. Aristolochic acid A sodium reduces BLCAP gene expression in human cell lines .
loading...
    loading...
11
11 Cited Publications
Cat. No.: HY-P1740
CAS No.: 114681-65-1
Target:  

Integrin Apoptosis Caspase

Research Areas:  

Inflammation/Immunology

RGD peptide (GRGDNP) is an inhibitor of integrin-ligand interactions. RGD peptide (GRGDNP) competitively inhibits α5β1 binding with extracellular matrice (ECM). RGD peptide (GRGDNP) promotes apoptosis through activation of conformation changes that enhance pro-caspase-3 activation and autoprocessing. RGD peptide (GRGDNP) plays an important role in cell adhesion, migration, growth, and differentiation .
loading...
    loading...
11
11 Cited Publications
Cat. No.: HY-P1740A
Target:  

Integrin Apoptosis

Research Areas:  

Inflammation/Immunology Cancer

RGD peptide (GRGDNP) TFA is an inhibitor of integrin-ligand interactions. RGD peptide (GRGDNP) TFA competitively inhibits α5β1 binding with extracellular matrice (ECM). RGD peptide (GRGDNP) TFA promotes apoptosis through activation of conformation changes that enhance pro-caspase-3 activation and autoprocessing. RGD peptide (GRGDNP) TFA plays an important role in cell adhesion, migration, growth, and differentiation .
loading...
    loading...
9
9 Cited Publications
Cat. No.: HY-N0269
CAS No.: 34221-41-5
Echinatin is a chalcone isolated from the Chinese herbal medicine Gancao with hepatoprotective and anti-inflammatory effects . Echinatin can be quickly absorbed and eliminated and extensively distributed with an absolute bioavailability of approximately 6.81% in Rat .
loading...
    loading...
8
8 Cited Publications
Cat. No.: HY-N0703
CAS No.: 51938-32-0
Schaftoside is a flavonoid found in a variety of Chinese herbal medicines, such as Eleusine indica. Schaftoside inhibits the expression of TLR4 and Myd88. Schaftoside also decreases Drp1 expression and phosphorylation, and reduces mitochondrial fission .
loading...
    loading...
7
7 Cited Publications
Cat. No.: HY-N1435
CAS No.: 114482-86-9
Oroxin B (OB) is a BBB-permeable flavonoid isolated from traditional Chinese herbal medicine Oroxylum indicum (L.) Vent. Oroxin B (OB) possesses obvious inhibitory effect and induces early apoptosis rather than late apoptosis on liver cancer cells through upregulation of PTEN, down regulation of COX-2, VEGF, PI3K, and p-AKT. Oroxin B (OB) selectively induces tumor-suppressive ER stress in malignant lymphoma cells .
loading...
    loading...
4
4 Cited Publications
Cat. No.: HY-A0104
CAS No.: 9004-65-3
Synonyms: Hypromellose (Viscosity:11250-21000mPa.s); (Hydroxypropyl)methyl cellulose (Viscosity:11250-21000mPa.s); Celacol HPM 5000 (Viscosity:11250-21000mPa.s)
HPMC (Viscosity:11250-21000mPa.s) is a hydrophilic, non-ionic cellulose ether used to form swellable-soluble matrices.
loading...
    loading...
4
4 Cited Publications
Cat. No.: HY-N0659
CAS No.: 55466-04-1
Jujuboside A is a glycoside extracted from Semen Ziziphi Spinosae, a Chinese herbal medicine used to treat insomnia and anxiety.
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-N0677
CAS No.: 786593-06-4
Dehydroandrographolide succinate can be extracted from herbal medicine Andrographis paniculata (Burm f) Nees, is widely used in research for viral pneumonia and viral upper respiratory tract infections because of its immunostimulatory, anti-infective and anti-inflammatory effect. Dehydroandrographolide succinate exerts antithrombotic effect. Dehydroandrographolide succinate significantly inhibits the platelet aggregation rate (ED50 = 386.9 mg/kg) by decreasing TXB2 levels. Dehydroandrographolide succinate mitigates muscle astrophy via the Akt/GSK3β and MuRF-1 pathways .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-W030778
CAS No.: 139-13-9
Synonyms: Triglycollamic acid
Research Areas:  

Others

Nitrilotriacetic acid is an orally active chelating agent for metal ions. Nitrilotriacetic acid is an aminotricarboxylic acid that can sequester metal ions as water soluble complexes. Nitrilotriacetic acid reacts with strong oxidizing agents such as hypochlorite, chlorine, ozone, or oxygen in the presence of palladium/carbon catalyst. Nitrilotriacetic acid interacts with solid phases such as cell membranes and bone matrices in the mammalian system. Nitrilotriacetic acid is classified as an epigenetic rodent carcinogen .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-159051
CAS No.: 39775-75-2
Dragendorff reagent is a potassium bismuth iodide solution composed of basic bismuth nitrate (Bi (NO3)3), 2,3-Dihydroxysuccinic acid (HY-N2436) and Potassium iodide (HY-Y0283). Dragendorff reagent is used to detect alkaloids and other nitrogen-containing compounds. Dragendorff reagent is applied for rapid screening of herbal products .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-N6584
CAS No.: 5092-09-1
Saikogenin A, extracted from a Chinese herbal plant called Tsai-Fu, is a dipeptidyl peptidase-IV (DPP-IV) inhibitor.
loading...
    loading...
Cat. No.: HY-A0104J
CAS No.: 9004-65-3
Synonyms: Hypromellose (Type II,Viscosity:5mPa.s); (Hydroxypropyl)methyl cellulose (Type II,Viscosity:5mPa.s); Celacol HPM 5000 (Type II,Viscosity:5mPa.s)
HPMC (Hypromellose) (Type II,Viscosity:5mPa.s) is a hydrophilic, non-ionic cellulose ether used to form swellable-soluble matrices. HPMC (Type II,Viscosity:5mPa.s) is widely used in agent formulations due to its biocompatibility, uncharged nature, solubility in water and thermoplastic behavior .
loading...
    loading...
Cat. No.: HY-N0716
CAS No.: 2086-83-1
Synonyms: Natural Yellow 18
Berberine (Natural Yellow 18) is an alkaloid isolated from the Chinese herbal medicine Huanglian, as an antibiotic. Berberine (Natural Yellow 18) induces reactive oxygen species (ROS) generation and inhibits DNA topoisomerase. Berberine (Natural Yellow 18) has antineoplastic properties. The sulfate form (HY-N0716B) improves bioavailability .
loading...
    loading...