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54 Results for "

house fly

" in MedChemExpress (MCE) Product Catalog:

Products (54)

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BDP9066

3 Cited Publications

Cat. No.: HY-111424

CAS No.: 2226507-04-4

Purity: 98.18%

Target:

Cdc42-binding kinase

Research Areas:

Cancer

BDP9066 is a potent and selective myotonic dystrophy-related Cdc42-binding kinase MRCK inhibitor with an IC₅₀ of 64 nM for MRCKβ in SCC12 cells, K_i values of 0.0136 nM and 0.0233 nM for MRCKα/β in house determinations, respectively. BDP9066 has therapeutic effect on skin cancer by reducing substrate phosphorylation.

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GCN2-IN-6

3 Cited Publications

Cat. No.: HY-130240

CAS No.: 2183470-09-7

Purity: 98.89%

Target:

Eukaryotic Initiation Factor (eIF)

Research Areas:

Cancer

GCN2-IN-6 (Compound 6d) is a potent, and orally available GCN2 inhibitor confirmed by in-house enzymatic (IC₅₀ of 1.8 nM) and cellular assays (IC₅₀ of 9.3 nM). GCN2-IN-6 is also a eIF2α kinase PERK inhibitor with an IC₅₀ of 0.26 nM (in enzymatic assay) and 230 nM (in cells) . GCN2-IN-6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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House Dust Mite Extract, from D.farinae

2 Cited Publications

Cat. No.: HY-NP159

House Dust Mite Extract, from D.farinae is a house dust mite allergen extract derived from Dermatophagoides farinae. House Dust Mite Extract, from D.farinae significantly increases the levels of cytokines (IL-4, IL-5, IL-6) in bronchoalveolar lavage fluid. House Dust Mite Extract, from D.farinae upregulates the overexpression of MUC5AC. House Dust Mite Extract, from D.farinae induces allergic asthma and pulmonary inflammation .

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