34 Results for "

human EBP

" in MedChemExpress (MCE) Product Catalog:
Products (34)

34 Results for "human EBP" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-N6954
CAS No.: 76996-27-5
Garcinone C, a xanthone derivative, is a natural compound extracted from Garcinia oblongifolia that is used as an anti-inflammatory, astringency and granulation-promoting medicine, and has potential cytotoxic effects on certain cancers. Garcinone C stimulates the expression levels of ATR and 4E-BP1, arrests the cell cycle, inhibits cell viability of the human Nasopharyngeal carcinoma (NPC) cell lines CNE1, CNE2, HK1 and HONE1 in a time‑ and dose‑dependent manner through inhibition of Hedgehog signaling pathway. Garcinone C is orally active .
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1
1 Cited Publications
Cat. No.: HY-P71259
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: RETN; Cysteine-Rich Secreted Protein FIZZ3; Resistin; RSTN; FIZZ3; C/EBP-Epsilon Regulated Myeloid-Specific Secreted Cysteine-Rich Protein Precursor 1; ADSF; Found In Inflammatory Zone 3; RETN1; Resistin Delta2; C/EBP-Epsilon-Regulated Myeloid-Specific Se
Species:  
Human
Source:  
E. coli
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1
1 Cited Publications
Cat. No.: HY-P81233
Synonyms: GADD153; CHOP; Growth arrest and DNA damage-inducible 153; C/EBP homologous protein; C/EBP Homology Protein; CEBPZ; CHOP10; DDIT 3; DNA Damage Inducible Transcript 3; GADD 153; Growth Arrest and DNA Damage Inducible Protein 153; Growth arrest and DNA damage inducible protein GADD153; MGC4154; DDIT3_human.

Host:  

Mouse

Application:  

WB, IHC-P, ICC/IF

Reactivity:  

Human, Mouse, Rat

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1
1 Cited Publications
Cat. No.: HY-P70303
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GLB1; Beta-Galactosidase; Prev. ELNR1; Elastin Receptor 1 (67kD); EBP; Galactosidase, Beta 1; Elastin Receptor 1, 67kDa; Elastin Receptor 1; Elastin Binding Protein; MPS4B; Acid Beta-Galactosidase; Galactosidase Beta 1; Lactase
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-162351
CAS No.: 3034437-44-7
Research Areas:  

Metabolic Disease

EBP-IN-1 is an orally active, blood-brain barrier-permeable inhibitor of emopamil binding protein (EBP). EBP-IN-1 has an IC50 of 8.2 μM against human ERG potassium channels (in CHO background). By inhibiting the sterol isomerase activity of EBP, EBP-IN-1 causes the accumulation of Zymostenol (HY-113345), and exhibits strong target binding in the brain after repeated administration in rodents. EBP-IN-1 also promotes oligodendrocyte formation in human cortical organoids and can be used in research related to multiple sclerosis .
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Cat. No.: HY-115590
CAS No.: 1902983-63-4
Research Areas:  

Cancer

JP-11646 is a pan-PIM inhibitor with increased potency against PIM2 (IC50 = 0.5 nM). JP11646 is freely reversible and ATP non-competitive. JP-11646 results in a decrease of PIM1, 2, and 3 mRNA. JP-11646 can effectively inhibit cell viability in small cell lung cancer (SCLC) and large cell neuroendocrine carcinomas of the lung (LCNEC). JP-11646 can cause a decrease in p-4EBP-1 protein, increasing the cleavage of caspases while decreasing caspase-3. JP-11646 induces apoptosis or necroptosis in cells. JP-11646 leads to reductions in MYC paralogs. JP-11646 can be used for the study of SCLC, LCNEC, human acute leukemia (AML), multiple myeloma (MM), and triple-negative breast cancer (TNBC) .
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Cat. No.: HY-P10323
Synonyms: Tumstatin (74-98), human
Target:  

Integrin FAK mTOR Apoptosis

Research Areas:  

Cancer

T7 Peptide is a protein synthesis inhibitor and anti-angiogenic agent, with a Kd of 10 nM for human transferrin receptor. T7 Peptide inhibits the phosphorylation of focal adhesion kinase, the activation of phosphatidylinositol 3-kinase and Akt, the kinase activity of mTOR, as well as the phosphorylation of 4E-BP1 in endothelial cells. T7 Peptide induces G0/G1 cell cycle arrest, apoptosis and protective autophagy in hepatocellular carcinoma cells, and suppresses tumor growth in mouse models. T7 Peptide is applicable to research related to cancer, glioblastoma, hepatocellular carcinoma and glioma .
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Cat. No.: HY-P10323A
Synonyms: Tumstatin (74-98), human TFA
Target:  

Integrin FAK mTOR Apoptosis

Research Areas:  

Cancer

T7 Peptide TFA is a protein synthesis inhibitor and anti-angiogenic agent, with a Kd of 10 nM for human transferrin receptor. T7 Peptide TFA inhibits the phosphorylation of focal adhesion kinase, the activation of phosphatidylinositol 3-kinase and Akt, the kinase activity of mTOR, as well as the phosphorylation of 4E-BP1 in endothelial cells. T7 Peptide TFA induces G0/G1 cell cycle arrest, apoptosis and protective autophagy in hepatocellular carcinoma cells, and suppresses tumor growth in mouse models. T7 Peptide TFA is applicable to research related to cancer, glioblastoma, hepatocellular carcinoma and glioma .
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Cat. No.: HY-130723A
Purity:  99.65%
Target:  

AMPK

Research Areas:  

Cancer

AMPK activator 2 (compound 7a) hydrochloride, a fluorine-containing proguanil derivative, up-regulates AMPK signal pathway and downregulates mTOR/4EBP1/p70S6K. AMPK activator 2 hydrochloride inhibits proliferation and migration of human cancer cell lines (UMUC3, T24, A549) .
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Cat. No.: HY-RS04130
Research Areas:  

Others

EBP Human Pre-designed siRNA Set A contains three designed siRNAs for EBP gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS04277
Research Areas:  

Others

EIF4EBP1 Human Pre-designed siRNA Set A contains three designed siRNAs for EIF4EBP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS04278
Research Areas:  

Others

EIF4EBP2 Human Pre-designed siRNA Set A contains three designed siRNAs for EIF4EBP2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS04279
Research Areas:  

Others

EIF4EBP3 Human Pre-designed siRNA Set A contains three designed siRNAs for EIF4EBP3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-130723
CAS No.: 2410961-69-0
Target:  

AMPK

Research Areas:  

Cancer

AMPK activator 2 (compound 7a), a fluorine-containing proguanil derivative, up-regulates AMPK signal pathway and downregulates mTOR/4EBP1/p70S6K. AMPK activator 2 inhibits proliferation and migration of human cancer cell lines (UMUC3, T24, A549) .
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Cat. No.: HY-N6954R
CAS No.: 76996-27-5
Garcinone C (Standard) is the analytical standard of Garcinone C. This product is intended for research and analytical applications. Garcinone C, a xanthone derivative, is a natural compound extracted from Garcinia oblongifolia that is used as an anti-inflammatory, astringency and granulation-promoting medicine, and has potential cytotoxic effects on certain cancers. Garcinone C stimulates the expression levels of ATR and 4E-BP1, arrests the cell cycle, inhibits cell viability of the human Nasopharyngeal carcinoma (NPC) cell lines CNE1, CNE2, HK1 and HONE1 in a time‑ and dose‑dependent manner through inhibition of Hedgehog signaling pathway. Garcinone C is orally active .
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Cat. No.: HY-P701227
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CEBPA; CCAAT/Enhancer Binding Protein (C/EBP), Alpha; Prev. CEBP; CCAAT/Enhancer Binding Protein Alpha; C/EBP-Alpha; C/EBP Alpha; CCAAT Enhancer Binding Protein Alpha; CCAAT/Enhancer-Binding Protein Alpha
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P74254
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CEBPG; CCAAT/Enhancer Binding Protein (C/EBP), Gamma; CCAAT Enhancer Binding Protein Gamma; CCAAT/Enhancer-Binding Protein Gamma; IG/EBP-1; C/EBP Gamma; GPE1BP; CCAAT/Enhancer Binding Protein Gamma
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P70416
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: EIF4EBP2; EIF4EBP2 Protein; Eukaryotic Translation Initiation Factor 4E Binding Protein 2; PHASII; Eukaryotic Translation Initiation Factor 4E-Binding Protein 2; 4E-BP2; EIF4E-Binding Protein 2; 4EBP2; Phosphorylated, Heat And Acid Stable Regulated By Ins
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P72134
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CEBPD; CCAAT/Enhancer Binding Protein (C/EBP), Delta; CCAAT Enhancer Binding Protein Delta; CCAAT/Enhancer-Binding Protein Delta; NF-IL6-Beta; Nuclear Factor NF-IL6-Beta; C/EBP-Delta; C/EBP Delta; CRP3; CCAAT/Enhancer Binding Protein Delta; CELF; CEBPD Pr
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P85622
Synonyms: 4E-BP2; 4EBP2; 4EBP2_human; eIF4E binding protein 2; eIF4E-binding protein 2; Eif4EBP2; Eukaryotic translation initiation factor 4E binding protein 1; Eukaryotic translation initiation factor 4E-binding protein 2; PHASII; phosphorylated, heat and acid stable regulated by insulin protein II.

Host:  

Mouse

Application:  

WB

Reactivity:  

Transfected

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