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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
human Granzyme B
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "human Granzyme B" in MCE Product Catalog:
Cat. No.: HY-P703940
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GZMB; Granzyme B (Granzyme 2, Cytotoxic T-Lymphocyte-Associated Serine Esterase 1); Prev. CTLA1; Cytotoxic Serine Protease B; Prev. CSPB; human Lymphocyte Protein; CTSGL1; Fragmentin-2; CGL1; C11; SECT; Cytotoxic T-Lymphocyte-Associated Serine Esterase 1
Species:
Human
Source:
HEK293
Cat. No.: HY-P86300
Synonyms: Granzyme B; C11; CTLA-1; Cathepsin G-like 1; CTSGL1; Cytotoxic T-lymphocyte proteinase 2; Lymphocyte protease; Fragmentin-2; Granzyme-2; human lymphocyte protein; HLP; SECT; T-cell serine protease 1-3E;
Cat. No.: HY-P992021
Target:
Research Areas:
Cat. No.: HY-P992524
PF-07260437 is a bispecific monoclonal antibody targeting B7-H4 and CD3, with Kd values of 63.5 nM and 66.75 nM against human and cynomolgus monkey CD3, respectively. PF-07260437 simultaneously binds B7-H4 on tumor cells and the CD3ε subunit in the T cell receptor complex, forming a tumor cell-bispecific antibody-T cell trimer. This process establishes an immune synapse and initiates non-MHC-dependent T cell activation, proliferation, and release of cytotoxic molecules such as granzyme B to kill tumor cells. PF-07260437 can be used in research related to advanced or metastatic breast cancer, ovarian cancer, and endometrial cancer .
Cat. No.: HY-184689
CAS No.: 1311892-52-0
ORS-14 is a LILRB4/ILT3 ligand with a Kd of 85.2 nM for human receptors. ORS-14 blocks SCG2-mediated LILRB4 signaling pathway, reverses SCG2-mediated immunosuppression, restores cytokine production, reduces tumor cell viability, recovers cytotoxic T cell function, and increases the frequency of granzyme B + CD8 + T cells. ORS-14 can be used in research related to colorectal cancer and acute myeloid leukemia .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
