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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
13 Results for "
human MMP-1
" in MedChemExpress (MCE) Product Catalog:
Products (13)
13 Results for "human MMP-1" in MCE Product Catalog:
67
67 Cited Publications
Synonyms: GM6001; Galardin
Ilomastat (GM6001) is a potent and broad spectrum matrix metalloprotease (MMP) inhibitor, inhibits MMPs (IC50s, 1.5 nM for MMP-1; 1.1 nM for MMP-2; 1.9 nM for MMP-3; 0.5 nM for MMP-9), with a Ki of 0.4 nM for human skin fibroblast collagenase (MMP-1).
1
1 Cited Publications
Cat. No.: HY-P70250
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MMP1; Matrix Metallopeptidase 1 (Interstitial Collagenase); Prev. CLG; Matrix Metalloproteinase 1; Interstitial Collagenase; Matrix Metalloprotease 1; Fibroblast Collagenase; Alternative Protein MMP1; Matrix Metalloproteinase 1 (Interstitial Collagenase); MMP-1; Matrix Metallopeptidase 1; Matrix Metalloproteinase-1
Species:
Human
Source:
HEK293
Cat. No.: HY-164159
CAS No.: 130603-71-3
Target:
Research Areas:
α-Glucosylrutin, a flavonoid, is a potent antioxidant with free radical scavenging activity. α-Glucosylrutin reduces MMP-1 gene expression, protein expression, and enzyme activity, and reduces MMP-2 protein expression and enzyme activity in UVA-irradiated human dermal fibroblasts. α-Glucosylrutin prevents oxidative stress-induced intracellular tyrosine residue phosphorylation and counteracts intracellular thiol level depletion in human skin cells. α-Glucosylrutin is effective in the prevention of dermatologic diseases in which oxidative stress is of pathogenetic relevance, e.g. in polymorphous light eruption (PLE). α-Glucosylrutin can be used for the research of UV-induced skin photodamage/photoaging .
Cat. No.: HY-N11072
CAS No.: 29836-40-6
Cat. No.: HY-W745164
CAS No.: 340167-81-9
Target:
Cat. No.: HY-RS08516
Target:
Research Areas:
MMP1 Human Pre-designed siRNA Set A contains three designed siRNAs for MMP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-15768R
CAS No.: 142880-36-2
Synonyms: GM6001 (Standard); Galardin (Standard)
Target:
Research Areas:
Ilomastat (Standard) is the analytical standard of Ilomastat. This product is intended for research and analytical applications. Ilomastat (GM6001) is a potent and broad spectrum matrix metalloprotease (MMP) inhibitor, inhibits MMPs (IC50s, 1.5 nM for MMP-1; 1.1 nM for MMP-2; 1.9 nM for MMP-3; 0.5 nM for MMP-9), with a Ki of 0.4 nM for human skin fibroblast collagenase (MMP-1).
Cat. No.: HY-P10775A
Cat. No.: HY-N12150
CAS No.: 108887-68-9
Category:
Plant Zingiberaceae Extract Terpenoids Sesquiterpenes Curcuma zanthorrhiza Roxburgh Extract
Target:
Cat. No.: HY-N12653
CAS No.: 99572-22-2
Synonyms: (-)-Exserohilone
Category:
Target:
Cat. No.: HY-P70250A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MMP1; Matrix Metallopeptidase 1 (Interstitial Collagenase); Prev. CLG; Matrix Metalloproteinase 1; Interstitial Collagenase; Matrix Metalloprotease 1; Fibroblast Collagenase; Alternative Protein MMP1; Matrix Metalloproteinase 1 (Interstitial Collagenase); MMP-1; Matrix Metallopeptidase 1; Matrix Metalloproteinase-1
Species:
Human
Source:
HEK293
Cat. No.: HY-137839
CAS No.: 927827-98-3
Target:
Research Areas:
Anti-inflammatory agent 121 is a protease inhibitor, with IC50 values against different targets as follows: 1.3 μM (Staphylococcus aureus type I staphylokinase), 2.2 μM (Staphylococcus aureus type II staphylokinase), 2.3 μM (human MMP-1), 2.7 μM (human MMP-2), 1.4 μM (human MMP-8), 4.6 μM (human MMP-9), and 79 μM (human ADAM17). Anti-inflammatory agent 121 inhibits the activities of staphylococcal serine protease glutamyl endopeptidase (V8 protease) and cysteine protease staphylococcal protease B in Staphylococcus aureus cultures. Anti-inflammatory agent 121 inhibits protease activity in skin wash samples, metalloprotease (staphylokinase) activity in Staphylococcus aureus culture supernatants, and staphylokinase-mediated activation of pro-urokinase-type plasminogen activator (pro-uPA). Anti-inflammatory agent 121 can be used in the research of atopic dermatitis .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
