32 Results for "

human NGF

" in MedChemExpress (MCE) Product Catalog:
Products (32)

32 Results for "human NGF" in MCE Product Catalog:

5
5 Cited Publications
Cat. No.: HY-P73316
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NGF; Beta-NGF; Prev. NGFB; Pro-Nerve Growth Factor Long; Beta-Nerve Growth Factor; HSAN5; Nerve Growth Factor (Beta Polypeptide); Nerve Growth Factor; Nerve Growth Factor, Beta Subunit
Species:  
Human
Source:  
CHO
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3
3 Cited Publications
Cat. No.: HY-P70456
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NTF3; Neurotrophin-3; Neurotrophin 3; NGF-2; NGF2; HDNF; Nerve Growth Factor 2; NT-3; Neurotrophic Factor; NT3
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P99195
CAS No.: 1190239-42-9
Synonyms: REGN475; SAR-164877
Target:  

Trk Receptor

Research Areas:  

Inflammation/Immunology

Fasinumab (Anti-Human NGF) is a human IgG4 monoclonal antibody to nerve growth factor (NGF). Fasinumab can be used in acute sciatica and knee osteoarthritis (OA) studies .
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Cat. No.: HY-P990474
Synonyms: AS2886401-00

Target:  

Trk Receptor

Research Areas:  

Inflammation/Immunology

Anti-NGF/bNGF Antibody is a CHO-expressed humanized antibody that targets NGF/bNGF. Anti-NGF/bNGF Antibody has a huIgG2 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 144.14 kDa. The isotype control for Anti-NGF/bNGF Antibody can be referenced as Human IgG2 kappa, Isotype Control (HY-P99002).
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Cat. No.: HY-P99200
CAS No.: 902141-80-4

Target:  

Trk Receptor

Research Areas:  

Neurological Disease

Fulranumab is a human IgG2 monoclonal antibody against nerve growth factor (NGF) and can be used for the research of pain .
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Cat. No.: HY-P991324

Research Areas:  

Inflammation/Immunology

MEDI-7352 is a human bispecific antibody (bsAb) targeting NGF/bNGF & TNF. MEDI-7352 can be used in osteoarthritis (OA) pain research .
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Cat. No.: HY-E70869
Target:  

Trk Receptor

Research Areas:  

Neurological Disease

TRKA (also named NTRK1) is a potential new member of the tyrosine kinase gene family. TRKA is a receptor tyrosine kinase that is phosphorylated in response to NGF. A single transmembrane domain divides TRKA into an extracellular domain, important for NGF binding, and an intracellular tyrosine kinase domain, important for signal transduction. TRKA(NTRK1) Recombinant Human Active Protein Kinase is a recombinant TRKA(NTRK1) protein that can be used to study TRKA(NTRK1)-related functions .
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Cat. No.: HY-P991622
MNAC13 is a kind of mouse IgG1 chimeric antibody, targeting to human TrkA. MNAC13 inhibits the NGF dependent signaling pathway by specifically binding to TrkA receptors. MNAC13 has good analgesic effect and long-lasting efficacy. MNAC13 can be used for researches on inflammatory and chronic pain .
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Cat. No.: HY-RS09277
Research Areas:  

Others

NGF Human Pre-designed siRNA Set A contains three designed siRNAs for NGF gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-59201A
CAS No.: 848591-90-2
A-582941 dihydrochloride is a selective, orally active, blood-brain barrier-permeable α7 nAChR agonist, with Ki values of 10.8 nM and 17 nM in rat brain and human frontal cortex, respectively. A-582941 dihydrochloride exhibits agonistic activity at 5-HT3 receptors, with a Ki of 150 nM. A-582941 dihydrochloride triggers phosphorylation of ERK1/2 and CREB, inhibits GSK-3β via Ser-9 phosphorylation, increases acetylcholine release, induces the expression of Arc and c-Fos, activates brain regions associated with working memory and attention, and reduces cell death caused by nerve growth factor (NGF) deprivation. A-582941 dihydrochloride is applicable for the research of Alzheimer's disease and schizophrenia .
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Cat. No.: HY-P991325

Target:  

Trk Receptor

Research Areas:  

Inflammation/Immunology

CRB-0089 is a human monoclonal antibody (mAb) targeting NGF/bNGF. CRB-0089 can be used in analgesia research.
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Cat. No.: HY-P990749
CAS No.: 2768355-18-4
Synonyms: AK-115

Target:  

Trk Receptor

Research Areas:  

Inflammation/Immunology

Luvagrobart is an anti-NGF human IgG1 κ monoclonal antibody . Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-P991323

Research Areas:  

Inflammation/Immunology

MEDI-1912 is a human monoclonal antibody (mAb) targeting NGF/bNGF. MEDI-1912 inhibits signaling through TrkA and p75 receptors. MEDI-1912 can be used in chronic pain research .
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Cat. No.: HY-E70785
Target:  

Trk Receptor

Research Areas:  

Cancer

TRKA is a member of the tropomyosin receptor kinase (TRK) family, and its primary binding ligand is nerve growth factor (NGF). TRKA G667C is a mutant of TRKA. TRKA G667C Recombinant Human Active Protein Kinase is a recombinant TRKA G667C protein that can be used to study TRKA G667C-related functions .
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Cat. No.: HY-P11480
CAS No.: 3105660-96-3
Target:  

Trk Receptor

Research Areas:  

Neurological Disease

TrkA/NGF-IN-1 (Peptide 19) is an inhibitor of protein-protein interactions between TrkA and NGF (IC50: 21 nM for human TrkA in PathHunter assay). TrkA/NGF-IN-1 shows an analgesic effect in a rat incisional pain model .
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Cat. No.: HY-P992345

Target:  

Trk Receptor

Research Areas:  

Neurological Disease

DS002 is a human monoclonal antibody targeting NGF/bNGF, with an IC50 of 6.60 nM against human NGF, 1.98 nM against rat NGF, and 8.46 nM against mouse NGF. DS002 blocks NGF-TrkA binding, interrupts pain signal transduction, inhibits TrkA-mediated downstream signaling pathways, and alters aromatic amino acid metabolic pathways. DS002 inhibits cancer cell proliferation. DS002 exerts a preventive effect on Paclitaxel-, Cisplatin- and Vincristine-induced peripheral neuropathy in rats. DS002 can be used in studies related to chronic pain and chemotherapy-induced peripheral neuropathy .
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Cat. No.: HY-P7660
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NGF; Beta-NGF; Prev. NGFB; Pro-Nerve Growth Factor Long; Beta-Nerve Growth Factor; HSAN5; Nerve Growth Factor (Beta Polypeptide); Nerve Growth Factor; Nerve Growth Factor, Beta Subunit
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P70449
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NGF; Beta-NGF; Prev. NGFB; Pro-Nerve Growth Factor Long; Beta-Nerve Growth Factor; HSAN5; Nerve Growth Factor (Beta Polypeptide); Nerve Growth Factor; Nerve Growth Factor, Beta Subunit
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P72488
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NGF; Beta-NGF; Prev. NGFB; Pro-Nerve Growth Factor Long; Beta-Nerve Growth Factor; HSAN5; Nerve Growth Factor (Beta Polypeptide); Nerve Growth Factor; Nerve Growth Factor, Beta Subunit
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P700018AF
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NGF; Beta-NGF; Prev. NGFB; Pro-Nerve Growth Factor Long; Beta-Nerve Growth Factor; HSAN5; Nerve Growth Factor (Beta Polypeptide); Nerve Growth Factor; Nerve Growth Factor, Beta Subunit
Species:  
Human
Source:  
E. coli
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