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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
15 Results for "
human NTPDase2
" in MedChemExpress (MCE) Product Catalog:
Products (15)
15 Results for "human NTPDase2" in MCE Product Catalog:
3
Target:
Research Areas:
Ticlopidine (PCR 5332), an antithrombotic proagent, acts as an allosteric, noncompetitive inhibitor of CD39 with the IC50 of 81.7 μM. Ticlopidine blocks several NTPDase isoenzymes with IC50s of 170 μM and 149 μM for NTPDase2 and NTPDase3, respectively. Ticlopidine is an inhibitor of CYP2C19 human liver cytochrome. Ticlopidine inhibits CYP2C9 and CYP3A4 with IC50s of 26.0 and 32.3 μM, respectively.
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3 Cited Publications
Cat. No.: HY-B0153A
CAS No.: 53885-35-1
Target:
Research Areas:
Ticlopidine (PCR 5332) hydrochloride, an antithrombotic proagent, acts as an allosteric, noncompetitive inhibitor of CD39 with the IC50 of 81.7 μM. Ticlopidine hydrochloride blocks several NTPDase isoenzymes with IC50s of 170 μM and 149 μM for NTPDase2 and NTPDase3, respectively. Ticlopidine hydrochloride is an inhibitor of CYP2C19 human liver cytochrome. Ticlopidine hydrochloride inhibits CYP2C9 and CYP3A4 with IC50s of 26.0 and 32.3 μM, respectively .
Cat. No.: HY-100386R
CAS No.: 55142-85-3
Synonyms: PCR 5332 (Standard)
Research Areas:
Ticlopidine (Standard) is the analytical standard of Ticlopidine. This product is intended for research and analytical applications. Ticlopidine (PCR 5332), an antithrombotic proagent, acts as an allosteric, noncompetitive inhibitor of CD39 with the IC50 of 81.7 μM. Ticlopidine blocks several NTPDase isoenzymes with IC50s of 170 μM and 149 μM for NTPDase2 and NTPDase3, respectively . Ticlopidine is an inhibitor of CYP2C19 human liver cytochrome. Ticlopidine inhibits CYP2C9 and CYP3A4 with IC50s of 26.0 and 32.3 μM, respectively .
Target:
Research Areas:
PSB-16131 is a potent inhibitor of human NTPDase2, showing non-competitive inhibition with an IC50 of 539 nM. PSB-16131 can be used in the study of inflammation, neurodegenerative diseases and cancer .
Target:
Research Areas:
Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
PSB-06126 is a selective nucleoside triphosphate diphosphohydrolase (NTPDase) inhibitor, with the Ki values of 0.33 μM for rat NTPDase 1, 19.1 μM for NTPDase 2 and 2.22 μM for NTPDase 3, respectively. PSB-06126 acts on human NTPDase 3 with an IC50 value of 7.76 μM and a Ki value of 4.39 μM .
Cat. No.: HY-100386S
CAS No.: 1246817-49-1
Synonyms: PCR 5332-d4
Cat. No.: HY-B0153AS
Cat. No.: HY-W707554
CAS No.: 2985259-58-1
Cat. No.: HY-B0153AR
CAS No.: 53885-35-1
Research Areas:
Ticlopidine hydrochloride (Standard) is the analytical standard of Ticlopidine hydrochloride (HY-B0153A). This product is intended for research and analytical applications. Ticlopidine (PCR 5332) hydrochloride, an antithrombotic proagent, acts as an allosteric, noncompetitive inhibitor of CD39 with the IC50 of 81.7 μM. Ticlopidine hydrochloride blocks several NTPDase isoenzymes with IC50s of 170 μM and 149 μM for NTPDase2 and NTPDase3, respectively . Ticlopidine hydrochloride is an inhibitor of CYP2C19 human liver cytochrome. Ticlopidine hydrochloride inhibits CYP2C9 and CYP3A4 with IC50s of 26.0 and 32.3 μM, respectively .
Cat. No.: HY-166530S
Cat. No.: HY-P72730
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ENTPD2; Ecto-ATPDase 2; Prev. CD39L1; E-NTPDase 2; NTPDase-2; NTPDase 2; Ecto-ATP Diphosphohydrolase 2; CD39-Like-1; CD39 Antigen-Like 1; Ecto-ATPase; Ectonucleoside Triphosphate Diphosphohydrolase 2; Ecto-ATPase 2
Species:
Human
Source:
HEK293
Cat. No.: HY-P76903
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: ENTPD2; Ecto-ATPDase 2; Prev. CD39L1; E-NTPDase 2; NTPDase-2; NTPDase 2; Ecto-ATP Diphosphohydrolase 2; CD39-Like-1; CD39 Antigen-Like 1; Ecto-ATPase; Ectonucleoside Triphosphate Diphosphohydrolase 2; Ecto-ATPase 2
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P704471
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ENTPD2; Ecto-ATPDase 2; Prev. CD39L1; E-NTPDase 2; NTPDase-2; NTPDase 2; Ecto-ATP Diphosphohydrolase 2; CD39-Like-1; CD39 Antigen-Like 1; Ecto-ATPase; Ectonucleoside Triphosphate Diphosphohydrolase 2; Ecto-ATPase 2
Species:
Human
Source:
CHO
Cat. No.: HY-103263R
CAS No.: 1052089-16-3
Target:
Research Areas:
Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
PSB-06126 (Standard) is the analytical standard of PSB-06126 (HY-103263). This product is intended for research and analytical applications. PSB-06126 is a selective nucleoside triphosphate diphosphohydrolase (NTPDase) inhibitor, with the Ki values of 0.33 μM for rat NTPDase 1, 19.1 μM for NTPDase 2 and 2.22 μM for NTPDase 3, respectively. PSB-06126 acts on human NTPDase 3 with an IC50 value of 7.76 μM and a Ki value of 4.39 μM .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
