5 Results for "

human OCT1

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "human OCT1" in MCE Product Catalog:

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GAPDH Protein, Human (HEK293, His)
GAPDH Protein, Human (HEK293, His)
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1 Cited Publications
Cat. No.: HY-P78776
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GAPDH; OCT1 Coactivator In S Phase, 38 Kd Component; Prev. GAPD; OCAS, P38 Component; Peptidyl-Cysteine S-Nitrosylase GAPDH; HEL-S-162eP; Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating); G3PD; Epididymis Secretory Sperm Binding Protein Li 162eP
Species:  
Human
Source:  
HEK293
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Murabutide
Murabutide
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Cat. No.: HY-106055
CAS No.: 74817-61-1
Target:  

HIV TNF Receptor Interleukin Related Apoptosis ATM/ATR NOD-like Receptor (NLR) CCR

Research Areas:  

Infection Inflammation/Immunology

Murabutide is an immunomodulator and also a NOD2 receptor agonist . Murabutide enhances the signal transduction of ATR and NOD2, mediates the activation of the DDR pathway, and thereby repairs radiation-induced DNA double-strand breaks. Murabutide inhibits radiation-induced cell apoptosis and protects cells and mice from radiation-induced toxic damage. Murabutide induces the expression and DNA-binding activity of Oct-1 in macrophages, thereby inhibiting the transcription and replication of HIV-1. Murabutide reduces the expression levels of CD4 and CCR5 on the surface of macrophages, and induces the secretion of β-chemokines, TNF-α and IL-6. Murabutide enhances non-specific viral resistance and targets reticuloendothelial cells. Murabutide can be used in research related to radiation-induced damage and human immunodeficiency virus type 1 infection .
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BMY 28674
BMY 28674
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Cat. No.: HY-100057
CAS No.: 125481-61-0
Synonyms: 6-Hydroxybuspirone; 6'-Hydroxybuspirone; BMS 528215
Target:  

5-HT Receptor Drug Metabolite Dopamine Receptor

Research Areas:  

Neurological Disease

BMY 28674 (6-Hydroxybuspirone) is the active metabolite of the anxiolytic buspirone (HY-B1115A) and is metabolized by CYP3A4.4. BMY 28674 binds to the serotonin (5-HT) receptor subtype 5-HT1A in the rat hippocampus and dorsal raphe (EC50s are 4 and 1 μM, respectively) and is an antagonist of dopamine D2, D3, and D4 receptors (IC50s are 3.1, 4.9, and 0.85 μM, respectively). BMY 28674 also inhibits organic cation transporter 1 (OCT1), OCT2, and OCT3 expressing human transporters in S2 proximal tubule cells in a concentration-dependent manner.
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Heliotridine
Heliotridine
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Cat. No.: HY-N21952
CAS No.: 520-63-8
Synonyms: (+)-Heliotridine
Category:  

Alkaloids Pyrrole Alkaloids Boraginaceae Extract Plants 500 - Internal Server Error | MedChemExpress

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