11 Results for "

human RBC

" in MedChemExpress (MCE) Product Catalog:
Products (11)

11 Results for "human RBC" in MCE Product Catalog:

11
11 Publications Verification
Cat. No.: HY-50694
CAS No.: 289656-45-7
Synonyms: ICA-17043
Target:  

Potassium Channel

Research Areas:  

Others

Senicapoc (ICA-17043) is a potent and selective Gardos channel (Ca 2+-activated K + channel; KCa3.1) blocker with an IC50 of 11 nM. Senicapoc blocks Ca 2+-induced rubidium flux from human RBCs with an IC50 value of 11 nM and inhibits RBC dehydration with IC50 of 30 nM .
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1
1 Cited Publications
Cat. No.: HY-106934A
CAS No.: 2772702-10-8
Purity:  99.63%
Synonyms: BCX 34 dihydrochloride
Peldesine (BCX 34) dihydrochloride is a potent, competitive, reversible and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC50s of 36 nM, 5 nM, and 32 nM for human, rat, and mouse red blood cell (RBC) PNP, respectively. Peldesine dihydrochloride is also a T-cell proliferation inhibitor with an IC50 of 800 nM. Peldesine dihydrochloride has the potential for cutaneous T-cell lymphoma, psoriasis and HIV infection research .
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Cat. No.: HY-P990068
CAS No.: 2643331-31-9
Synonyms: SRF617

Target:  

NTPDase

Research Areas:  

Inflammation/Immunology Cancer

Perenostobart (SRF617) is a human IgG4 antibody with inhibitory activity against CD39 ATPase. Perenostobart inhibits CD39-mediated hydrolysis of extracellular ATP to AMP, with IC50 values of 1.9 nM (HEK293 OE cells), 0.7 nM (MOLP-8 cells), and 1.2 nM (RBC-lysed whole blood). Perenostobart enhances CD4 + T-cell proliferation, promotes dendritic cell maturation, and boosts inflammasome activation in macrophages in the presence of ATP. Perenostobart demonstrates significant single-agent anti-tumor efficacy in MOLP-8 and H520 xenograft models. Perenostobart can be used for the study of cancer .
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Cat. No.: HY-125987
CAS No.: 381186-64-7
Purity:  98.88%
Target:  

Ras

Research Areas:  

Cancer

RBC6 is an inhibitor of GTPases RalA. RBC6 inhibits binding of Ral to its effector RALBP1. RBC6 also inhibits Ral-mediated cell spreading of murine embryonic fibroblasts, as well as anchorage-independent growth of human cancer celllines .
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Cat. No.: HY-168373
CAS No.: 99264-98-9
Target:  

Endogenous Metabolite

Research Areas:  

Others

1-Stearoyl-2-eicosapentaenoyl-sn-glycero-3-PC is a phospholipid that can be found in human red blood cells (RBCs) .
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Cat. No.: HY-106934
CAS No.: 133432-71-0
Synonyms: BCX 34
Peldesine (BCX 34) is a potent, competitive, reversible and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC50s of 36 nM, 5 nM, and 32 nM for human, rat, and mouse red blood cell (RBC) PNP, respectively. Peldesine is also a T-cell proliferation inhibitor with an IC50 of 800 nM. Peldesine has the potential for cutaneous T-cell lymphoma, psoriasis and HIV infection research .
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Cat. No.: HY-123464
CAS No.: 362503-73-9
Purity:  ≥98.0%
Target:  

Ras

Research Areas:  

Cancer

RBC10 is an anti-cancer agent. RBC10 inhibits the binding of Ral to its effector RALBP1. RBC10 also inhibits Ral-mediated cell spreading of murine embryonic fibroblasts and anchorage-independent growth of human cancer cell lines .
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Cat. No.: HY-50694R
CAS No.: 289656-45-7
Synonyms: ICA-17043 (Standard)
Research Areas:  

Others

Senicapoc (Standard) is the analytical standard of Senicapoc. This product is intended for research and analytical applications. Senicapoc (ICA-17043) is a potent and selective Gardos channel (Ca2+-activated K+ channel; KCa3.1) blocker with an IC50 of 11 nM. Senicapoc blocks Ca2+-induced rubidium flux from human RBCs with an IC50 value of 11 nM and inhibits RBC dehydration with IC50 of 30 nM .
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Cat. No.: HY-P990846

Research Areas:  

Metabolic Disease

Anti-Fy3 Antibody (MIMA-29) is a kind of mouse IgG2a κ chimeric antibody inhibitor, targeting to human Fy3. Anti-Fy3 Antibody (MIMA-29) binds to erythrocytes and induces RBC (red blood cells) clearance. Anti-Fy3 Antibody (MIMA-29) can be used for the research of metabolic disease .
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Cat. No.: HY-106934AR
CAS No.: 2772702-10-8
Synonyms: BCX 34 dihydrochloride (Standard)
Peldesine (dihydrochloride) (Standard) is the analytical standard of Peldesine (dihydrochloride). This product is intended for research and analytical applications. Peldesine (BCX 34) dihydrochloride is a potent, competitive, reversible and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC50s of 36 nM, 5 nM, and 32 nM for human, rat, and mouse red blood cell (RBC) PNP, respectively. Peldesine dihydrochloride is also a T-cell proliferation inhibitor with an IC50 of 800 nM. Peldesine dihydrochloride has the potential for cutaneous T-cell lymphoma, psoriasis and HIV infection research .
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Cat. No.: HY-P71210
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PKLR; Pyruvate Kinase, Liver And Blood Cell; Pyruvate Kinase L/R; Pyruvate Kinase Isozymes R/L; Pyruvate Kinase, Liver And RBC; Pyruvate Kinase Isozyme R/L; Red Cell/Liver Pyruvate Kinase; Pyruvate Kinase Isoform 1; R-Type/L-Type Pyruvate Kinase; Pyruvate Kinase Type L; Pyruvate Kinase Isozymes L/R; Pyruvate Kinase; Pyruvate Kinase PKLR; CNSHA2; Pyruvate Kinase 1; PKRL; PK1; RPK; PKL
Species:  
Human
Source:  
HEK293
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