8 Results for "

human intestinal absorption

" in MedChemExpress (MCE) Product Catalog:
Products (8)

8 Results for "human intestinal absorption" in MCE Product Catalog:

1
TP0463518
TP0463518
0 Images
1 Cited Publications
Cat. No.: HY-112144
CAS No.: 1558021-37-6
Purity:  99.25%
Target:  

HIF/HIF Prolyl-Hydroxylase

Research Areas:  

Metabolic Disease Inflammation/Immunology

TP0463518 is an orally active, competitive pan-inhibitor of hypoxia-inducible factor prolyl hydroxylases PHD1/2/3. TP0463518 competitively inhibits human PHD1 (IC50=18 nM), PHD2 (Ki=5.3 nM), and PHD3 (IC50=63 nM), and targets monkey PHD2 with an IC50 of 22 nM. TP0463518 inhibits PHD-catalyzed hydroxylation to stabilize HIFα, thereby upregulating erythropoietin (EPO) expression and enhancing intestinal iron absorption (such as increased DMT-1 and dCYTb expression), improving anemia. TP0463518 is mainly used for the research of renal anemia and inflammatory anemia .
loading...
    loading...
View All Sizes
Arabinoxylan (Medium viscosity)
Arabinoxylan (Medium viscosity)
0 Images
Cat. No.: HY-N15135
CAS No.: 9040-27-1
Category:  

Polysaccharides Antibiotics 500 - Internal Server Error | MedChemExpress

Oops!

Sorry, Something went wrong on our server.
Our team has been notified and is working to fix the issue.