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102 Results for "

human platelet aggregation

" in MedChemExpress (MCE) Product Catalog:

Products (102)

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Adenosine 5'-diphosphate

12 Publications Verification

Cat. No.: HY-W010918

CAS No.: 58-64-0

Synonyms: Adenosine diphosphate; ADP

Category:

Ketones, Aldehydes, Acids Endogenous metabolite

Target:

Endogenous Metabolite

Adenosine 5'-diphosphate (Adenosine diphosphate) is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P_2T-purinoceptors.

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Adenosine 5'-diphosphate sodium salt

11 Cited Publications

Cat. No.: HY-W010791

CAS No.: 20398-34-9

Target:

Endogenous Metabolite

Research Areas:

Others

Adenosine 5'-diphosphate sodium salt is a nucleoside diphosphate and the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate sodium salt induces human platelet aggregation and inhibits stimulated adenylate cyclase through its action on P_2T-purinergic receptors .

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Human α-Thrombin (Lyophilized)

9 Cited Publications

Cat. No.: HY-114164H

CAS No.: 9002-04-4

Synonyms: EC 3.4.21.5 (Lyophilized); human Alpha Thrombin (Lyophilized)

Target:

Ser/Thr Protease Thrombin Protease Activated Receptor (PAR) Factor Xa

Research Areas:

Cardiovascular Disease

Human α-Thrombin (EC 3.4.21.5; Human Alpha Thrombin) (Lyophilized) is a terminal serine protease in the coagulation cascade, as well as a potent physiological platelet agonist and fibrin-generating enzyme in vivo. Human α-Thrombin catalyzes the conversion of fibrinogen to fibrin for blood clot formation, and activates platelet aggregation by cleaving the protease-activated receptors PAR1 (major) (K_d = 1 nM) and PAR4 (minor) on the platelet surface to expose tethered ligands. Human α-Thrombin also amplifies coagulation via positive feedback by activating coagulation factors V, VIII, XI (FV/FVIII/FXI), and switches to activate protein C to exert anticoagulant effects after binding to thrombomodulin .
This product is in a freeze-dried form.

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HSA Protein

5 Cited Publications

Cat. No.: HY-P1956

CAS No.: 70024-90-7

Synonyms: human serum albumin

Target:

NF-κB NO Synthase

Research Areas:

Cardiovascular Disease Inflammation/Immunology Cancer

HSA Protein (Human serum albumin) is the most abundant protein in plasma and is a major determinant of plasma oncotic pressure. HSA Protein exhibits antioxidant, anticoagulant, anti-inflammatory, anti-platelet aggregation activities as well as colloid osmotic action. HSA Protein can block the inhibitory effect of GML on human T cells, providing protective function for T cells. HSA Protein is also associated with cardiovascular diseases and can partially prevent the LPS (HY-D1056) induced oxidative stress, as well as the upregulation of NF-κB, NF-κB, and peroxynitrite (ONOO ^-) in the vascular wall, contributing to the reduction of blood pressure .
This product is recombinant HSA Protein expressed in a microbial expression system.

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