19 Results for "

human polymorphonuclear leukocytes

" in MedChemExpress (MCE) Product Catalog:
Products (19)

19 Results for "human polymorphonuclear leukocytes" in MCE Product Catalog:

2
Cethromycin
Cethromycin
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2 Cited Publications
Cat. No.: HY-19655
CAS No.: 205110-48-1
Synonyms: ABT-773; Abbott-195773; A-195773
Target:  

Antibiotic Bacterial Parasite TNF Receptor IFNAR Interleukin Related

Research Areas:  

Infection Inflammation/Immunology

Cethromycin (ABT-773; Abbott-195773) is an orally effective ketolide antibiotic with broad-spectrum antibacterial activity. Cethromycin binds to domains II/V of the 23S rRNA of the 50S subunit, inhibiting bacterial protein synthesis. Cethromycin can accumulate in lung tissue, alveolar macrophages, epithelial lining fluid, and human polymorphonuclear leukocytes. Cethromycin exhibits potent in vitro activity against a variety of respiratory pathogens, including Mycoplasma pneumoniae. Cethromycin exhibits significant intracellular and pulmonary enrichment and anti-inflammatory effects against mycoplasma pneumonia in mouse models, improving airway obstruction and airway hyperresponsiveness. Cethromycin disrupts the apicoplast and reduces liver-stage parasite burden during the liver stage of Plasmodium berghei. Cethromycin can be used in research related to pneumonia, Staphylococcus aureus infection, gonorrhea, and malaria .
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Glaucine
Glaucine
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Cat. No.: HY-N3945
CAS No.: 475-81-0
Synonyms: O,O-Dimethylisoboldine; S-(+)-Glaucine; NSC 34396
Category:  

Infection Alkaloids Plants Other Families Extract Disease Research Fields Isoquinoline Alkaloids Inflammation/Immunology Papaveraceae Extract 500 - Internal Server Error | MedChemExpress

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