124 Results for "

hybrid

" in MedChemExpress (MCE) Product Catalog:
Products (124)

124 Results for "hybrid" in MCE Product Catalog:

13
Phen-DC3 Trifluoromethanesulfonate
Phen-DC3 Trifluoromethanesulfonate
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13 Publications Verification
Cat. No.: HY-15594A
CAS No.: 929895-45-4
Purity:  98.99%
Synonyms: Phen-DC3 Triflate
Target:  

G-quadruplex α-synuclein RIP kinase

Research Areas:  

Neurological Disease Inflammation/Immunology

Phen-DC3 Trifluoromethanesulfonate is a bisquinolinium G-quadruplex (G4) ligand. Phen-DC3 Trifluoromethanesulfonate selectively binds to and stabilizes the hybrid quadruplex-duplex hybrid (QDH) derived from the PIM1 promoter. Phen-DC3 Trifluoromethanesulfonate also binds to the c-myc promoter Pu24T G4 via extensive π-stacking, and induces polymerase stalling at α-synuclein DNA and RNA G4 sequences. Phen-DC3 Trifluoromethanesulfonate downregulates LPS (HY-D1056)-induced TNFRSF21, RIPK3 and p-MLKL in VECs, and ameliorates CLP-induced pulmonary vascular leakage in septic rats. Phen-DC3 Trifluoromethanesulfonate can be used in studies related to neurodegenerative diseases and sepsis-associated vascular injury .
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(2E)-Diethyl fumarate
(2E)-Diethyl fumarate
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1 Cited Publications
Cat. No.: HY-W010056
CAS No.: 623-91-6
Category:  

Natural Products Endogenous metabolite Disease Research Fields Inflammation/Immunology

Target:  

Keap1-Nrf2

Diethyl fumarate is a Nrf2 inducer. Diethyl fumarate induces non-immunological contact urticaria, causing erythema, edema, and dose-dependent skin responses characterized by rapid onset, peak response, and subsequent resolution. The hybrid of Diethyl fumarate and Curcumin (HY-N0005) exerts neuroprotective effects. Diethyl fumarate can be used in the research of Parkinson's disease and non-immunological contact urticaria .
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TPMPA
TPMPA
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1 Cited Publications
Cat. No.: HY-101359
CAS No.: 182485-36-5
Purity:  98.1%
Target:  

GABA Receptor

Research Areas:  

Neurological Disease

TPMPA, a hybrid of isoguvacine and 3-APMPA, is the first selective antagonist for a GABAC receptor (KB = 2.1 μM), but not to interact with GABAA (KB = 320 μM) or GABAB receptors (EC50 = 500 μM). TPMPA has the potential for the research of suppressing orientation selectivity in ganglion cells .
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RNase H
RNase H
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1 Cited Publications
Cat. No.: HY-KE7058

RNase H is an endoribonuclease expressed and purified from Escherichia coli and can specifically hydrolyze RNA in DNA-RNA hybrid strands.

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Sodium pyrophosphate
Sodium pyrophosphate
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1 Cited Publications
Cat. No.: HY-W105970
CAS No.: 7758-16-9
Synonyms: Disodium pyrophosphate; Sodium acid pyrophosphate; SAPP
Sodium pyrophosphate (Disodium pyrophosphate) is an orally active reverse transcriptase ribonuclease H inhibitor. Sodium pyrophosphate forms soluble complexes with iron from ferric pyrophosphate to promote intestinal iron absorption. Sodium pyrophosphate increases the β-sheet content of oxidatively damaged myofibrillar protein gels and enhances the gastric digestibility and antioxidant activity of their digestion products. Sodium pyrophosphate prevents the degradation of RNA-DNA hybrids, inhibits antisense complementary DNA synthesis, induces phage DNA leakage, and causes random mutations in temperate phages .
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Endo-β-N-acetylglucosaminidase F1
Endo-β-N-acetylglucosaminidase F1
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Cat. No.: HY-E70135
CAS No.: 37278-88-9
Synonyms: Endo F1
Target:  

Endonuclease

Research Areas:  

Metabolic Disease

Endo-β-N-acetylglucosaminidase F1 (Endo F1) cleaves Asparagine-linked high mannose and some hybrid oligosaccharides .
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Polyoxyethylene (10) lauryl ether
Polyoxyethylene (10) lauryl ether
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Cat. No.: HY-B2106D
CAS No.: 9002-92-0
Synonyms: Decaethylene glycol monododecyl ether (C12E10); Polidocanol (10)
Polyoxyethylene (10) lauryl ether is a nonionic surfactant. Polyoxyethylene (10) lauryl ether exhibits unique properties in dissolving liposomes and exerts the minimal interference with endotoxin detection. Polyoxyethylene (10) lauryl ether forms hybrid liposomes with Dimyristoylphosphatidylcholine (DMPC) (HY-109541), which can inhibit the proliferation of human promyelocytic leukemia cells without the administration of any drugs .
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Furaneol
Furaneol
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Cat. No.: HY-N7093
CAS No.: 3658-77-3
Synonyms: Strawberry furanone
Category:  

Vitaceae Extract Microorganisms Ketones, Aldehydes, Acids Other Diseases 500 - Internal Server Error | MedChemExpress

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