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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
55 Results for "
hyperpigmentation
" in MedChemExpress (MCE) Product Catalog:
Products (55)
55 Results for "hyperpigmentation" in MCE Product Catalog:
6
6 Publications Verification
Cat. No.: HY-P70781
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: KITLG; SLF; Prev. MGF; Familial Progressive hyperpigmentation 2; SCF; Steel Factor; Mast Cell Growth Factor; C-Kit Ligand; Stem Cell Factor; Kit Ligand; DFNA69; SHEP7; Kitl; DCUA; KL-1; FPHH; FPH2; WS2F; KIT Ligand; SF
Species:
Human
Source:
E. coli
3
3 Cited Publications
Cat. No.: HY-P70528
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: KITLG; SLF; Prev. MGF; Familial Progressive hyperpigmentation 2; SCF; Steel Factor; Mast Cell Growth Factor; C-Kit Ligand; Stem Cell Factor; Kit Ligand; DFNA69; SHEP7; Kitl; DCUA; KL-1; FPHH; FPH2; WS2F; KIT Ligand; SF
Species:
Mouse
Source:
E. coli
3
3 Cited Publications
Cat. No.: HY-P70555
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: KITLG; SLF; Prev. MGF; Familial Progressive hyperpigmentation 2; SCF; Steel Factor; Mast Cell Growth Factor; C-Kit Ligand; Stem Cell Factor; Kit Ligand; DFNA69; SHEP7; Kitl; DCUA; KL-1; FPHH; FPH2; WS2F; KIT Ligand; SF
Species:
Mouse
Source:
HEK293
1
1 Cited Publications
Synonyms: Quercetin-3,3',4',7-tetramethylether
1
1 Cited Publications
Cat. No.: HY-P70757G
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: KITLG; SLF; Prev. MGF; Familial Progressive hyperpigmentation 2; SCF; Steel Factor; Mast Cell Growth Factor; C-Kit Ligand; Stem Cell Factor; Kit Ligand; DFNA69; SHEP7; Kitl; DCUA; KL-1; FPHH; FPH2; WS2F; KIT Ligand; SF
Species:
Human
Source:
HEK293
Cat. No.: HY-N3002
CAS No.: 84380-01-8
Synonyms: 4-Hydroxyphenyl α-D-glucopyranoside
Category:
Monophenols Metabolic Disease Phenols Ericaceae Extract Cosmetic Research Plants Disease Research Fields
Target:
Cat. No.: HY-W251181
CAS No.: 1428450-95-6
Target:
Research Areas:
Isobutylamido thiazolyl resorcinol is a selective hTyr inhibitor with an IC50 of 1.1 μM. Isobutylamido thiazolyl resorcinol shows an IC50 of 108 μM against mushroom Tyrosinase. Isobutylamido thiazolyl resorcinol effectively prevents pigmentation caused by UVB irradiation. Isobutylamido thiazolyl resorcinol significantly improves the visibility of acne-induced hyperpigmentation .
Category:
Natural Products Moraceae Extract Plants Endogenous metabolite Human Gut Microbiota Metabolites Ficus carica L. Other Diseases Phenols Polyphenols Disease Research Fields
Target:
Cat. No.: HY-N3266
CAS No.: 99353-00-1
Cat. No.: HY-P3452
CAS No.: 1036207-61-0
Target:
Research Areas:
Cat. No.: HY-N3200
CAS No.: 53734-74-0
Target:
Cat. No.: HY-W015782
CAS No.: 2896-60-8
Category:
Umbelliferae Extract Metabolic Disease Phenols Polyphenols Plants Disease Research Fields Echinacea angustifolia DC.
Target:
Target:
TSPO TRP Channel Microphthalmia Associated Transcription Factor (MITF) PKC PKA p38 MAPK PERK Interleukin Related
Research Areas:
FGIN-1-27 is a blood-brain barrier-penetrant TSPO ligand with a Ki value of 5 nM. FGIN 1-27 inhibits PKC-β, PKA/CREB, p38/ERK MAPK, MITF, tyrosinase, TRP-1, and TRP-2, thereby inhibiting melanogenesis and pigmentation. FGIN-1-27 alleviates X-ray radiation-induced astrocyte mitochondrial hyperfunction, reduces ROS and superoxide production, inhibits excessive activation of A1-type astrocytes, downregulates GFAP and C3 protein expression, and restores astrocyte proliferative capacity. FGIN-1-27 produces anticonvulsant effects in normal mice; in diazepam-withdrawn mice, the brain MDR pathway becomes subsensitive, and the anticonvulsant activity disappears. FGIN-1-27 attenuates pigmentation in zebrafish embryos and ameliorates UVB-induced skin pigmentation in guinea pigs. FGIN-1-27 directly stimulates testicular Leydig cells while upregulating luteinizing hormone levels, causing an acute increase in serum testosterone in male rats. FGIN 1-27 can be used for research related to hyperpigmentation, epilepsy, brain injury, and other diseases .
Cat. No.: HY-135014
CAS No.: 175357-18-3
Research Areas:
Undecylenoyl phenylalanine is an antagonist for α-melanocyte-stimulating hormone (MSH) and β-adrenergic receptor (β-ADR) to reduce the melanogenesis in melanocytes, reduces hyperpigmentation and thus ameliorates melasma lesions and solar lentigines .
Cat. No.: HY-161612
CAS No.: 149092-45-5
Target:
Research Areas:
Mycosporine 2 glycine is an anti-inflammatory agent and TYRP1 inhibitor. Mycosporine 2 glycine inhibits the expression of inflammatory genes and reduces nitric oxide production. Mycosporine 2 glycine binds tightly to the active pocket of TYRP1 and inhibits the activity of melanogenesis-related enzymes. Mycosporine 2 glycine can be used in the research of hyperpigmentation and inflammation-related diseases .
Category:
Alkaloids Metabolic Disease Phenols Polyphenols Nymphaeaceae Extract Nelumbo nucifera Gaertn. Plants Disease Research Fields Isoquinoline Alkaloids
Target:
Cat. No.: HY-N2134
CAS No.: 103654-50-8
Synonyms: Puerarin apioside
Category:
Flavonoids Phenols Polyphenols Plants Other Families Extract Disease Research Fields Endocrinology Isoflavones
Target:
Cat. No.: HY-148400
CAS No.: 913541-96-5
Synonyms: TXC hydrochloride
Target:
Research Areas:
Cetyl tranexamate (TXC) hydrochloride is an ester derivative of Tranexamic acid (HY-B0149). Cetyl tranexamate hydrochloride is an inhibitor of fibrinogen activation and can reduce the production of fibrinogen in keratinocytes induced by ultraviolet rays or damage, indirectly inhibiting the melanin production pathway. Cetyl tranexamate hydrochloride also targets melanin (dark spots) and hemoglobin (red spots), reducing vascular dilation and pigmentation by inhibiting inflammatory mediators (such as prostaglandins, platelet activating factors). Cetyl tranexamate hydrochloride can be used as a cosmetic ingredient and is suitable for epidermal pigment disorders such as photoaging, post-inflammatory hyperpigmentation (PIH), and melasma .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
