2 Results for "

hyphal structure

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "hyphal structure" in MCE Product Catalog:

Cat. No.: HY-136461
CAS No.: 22976-86-9
Synonyms: Polyoxorim
Target:  

Fungal Antibiotic

Research Areas:  

Infection

Polyoxin D (Polyoxorim) is an Antifungal Antibiotic. Polyoxin D inhibits Chitin synthase with an I50 of 1 mM for Stomoxys calcitrans chitin synthase. Polyoxin D causes swelling and rupture of fungal hyphal tips and budding yeast cells, haustorial encasement, haustorial wall thickening, widening of the extrahaustorial matrix, and cytoplasmic vesicles and tubular structures. Polyoxin D causes swelling of filamentous chains in Candida albicans and morphological changes in Agaricus bisporus and Coprinus cinereus. Polyoxin D is used in research on bean rust and Candida albicans infections .
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Cat. No.: HY-N15600
CAS No.: 68053-32-7
Synonyms: (-)-Merulidial
Merulidial (Compound 1) is an antibiotic and cytotoxic agent with a sesquiterpene dialdehyde structure. Merulidial significantly inhibits the germination of spores and the hyphal growth of the wood-roting basidiomycete Heterobasidion annosum (H. annosum) and the saprophytic mould Cladosporium cucumerinum (C.cucumerinum). Merulidial also inhibits a variety of bacteria, algae and DNA synthesis of ECA cells. Merulidial shows a strong anticancer activity with IC50 s of 20 and 10 μg/mL for ECA and L1210 cells, respectively .
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