57 Results for "

hypothermia

" in MedChemExpress (MCE) Product Catalog:
Products (57)

57 Results for "hypothermia" in MCE Product Catalog:

6
RN-1747
RN-1747
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6 Publications Verification
Cat. No.: HY-19976
CAS No.: 1024448-59-6
Target:  

TRP Channel

Research Areas:  

Cardiovascular Disease Metabolic Disease

RN-1747 is a selective TRPV4 channel agonist, with EC50 values of 0.77 μM, 4.0 μM and 4.1 μM for hTRPV4, mTRPV4 and rTRPV4, respectively. RN-1747 acts as an antagonist of TRPM8, with an IC50 of 4 μM. Topical cutaneous administration of RN-1747 induces hypothermia, increases tail heat loss via cutaneous vasodilation, and promotes cold-seeking behavior in rats. Intracerebroventricular administration of RN-1747 does not induce hypothermia in rats .
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5
Dihydrocapsaicin
Dihydrocapsaicin
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5 Cited Publications
Cat. No.: HY-N0361
CAS No.: 19408-84-5
Category:  

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