18 Results for "

immunogenic antigen

" in MedChemExpress (MCE) Product Catalog:
Products (18)

18 Results for "immunogenic antigen" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P1585
CAS No.: 212370-40-6
Synonyms: Hgp100 (25-33)
Target:  

MHC

Research Areas:  

Cancer

Gp100 (25-33), human (Hgp100 (25-33)) is the amino acids 25-33 fragment of the human melanoma antigen. Gp100 (25-33), human is a 9-amino acid (AA) epitope restricted by MHC class I H-2D b and recognized by the T cells. Gp100 (25-33), human has immunogenicity and induces specific T cells. Gp100 (25-33), human can be used for the cancer research, such as melanoma .
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1 Cited Publications
Cat. No.: HY-P9932
CAS No.: 1351337-07-9
Synonyms: ETI 204

Target:  

Bacterial

Research Areas:  

Infection Cardiovascular Disease

Obiltoxaximab (ETI 204) is the second and potent anti-protective antigen (PA) monoclonal antibody with immunogenicity. Obiltoxaximab plays a central role in anthrax toxin assembly and target cell intoxication, promoting survival, and inhibiting bacterial spread to the periphery in animal models. Obiltoxaximab can be used in the research of inhalational anthrax, bacteremia and toxemia .
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1 Cited Publications
Cat. No.: HY-P1585A
Synonyms: Hgp100 (25-33) TFA
Target:  

MHC

Research Areas:  

Cancer

Gp100 (25-33), human TFA (Hgp100 (25-33) (TFA)) is the amino acids 25-33 fragment of the human melanoma antigen. Gp100 (25-33), human TFA is a 9-amino acid (AA) epitope restricted by MHC class I H-2D b and recognized by the T cells. Gp100 (25-33), human TFA has immunogenicity and induces specific T cells. Gp100 (25-33), human TFA can be used for the cancer research, such as melanoma .
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Cat. No.: HY-155909A
CAS No.: 92451-01-9
Purity:  ≥80.0%
Synonyms: mPEG1000-SC; mPEG1000-Succinimidyl ester
m-PEG1000-NHS ester (mPEG1000-SC; mPEG1000-Succinimidyl ester) is a polyethylene glycol (PEG)-based biocompatibility-enhancing modifier. m‑PEG1000‑NHS ester enables PEGylation of molecules such as proteins, which reduces the immunogenicity and antigenicity of target molecules, decreases the tendency of protein aggregation, and protects proteins from hydrolysis. m-PEG1000-NHS ester can be used in drug delivery-related research .
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Cat. No.: HY-157745
CAS No.: 92451-01-9
Purity:  ≥98.0%
Synonyms: mPEG40000-SC; mPEG40000-Succinimidyl ester
Research Areas:  

Others

m-PEG-NHS ester (mPEG-SC; mPEG-Succinimidyl ester) (MW 40000) is a polyethylene glycol derivative. m-PEG-NHS ester serves as a modifying agent that reacts with free amino groups on the surface of protein or polypeptide molecules to form stable amide bonds, thereby covalently linking PEG chains to biomacromolecules, improving their antigenicity and immunogenicity, and facilitating the preparation of injectable formulations .
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Cat. No.: HY-P1778A
Target:  

HPV

Research Areas:  

Infection

HPV16 E7 (86-93) TFA is a human leukocyte antigen (HLA)-A2.1 restricted HPV16 E7-derived peptide. HPV16 E7 (86-93) TFA is immunogenic in cervical carcinomas .
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Cat. No.: HY-155909C
CAS No.: 92451-01-9
Purity:  ≥90.0%
Synonyms: mPEG350-SC; mPEG350-Succinimidyl ester
Research Areas:  

Others

m-PEG350-NHS ester (mPEG350-SC; mPEG350-Succinimidyl ester) is a polyethylene glycol (PEG)-based biocompatibility-enhancing modifier. m‑PEG350‑NHS ester enables PEGylation of molecules such as proteins, which reduces the immunogenicity and antigenicity of target molecules, decreases the tendency of protein aggregation, and protects proteins from hydrolysis. m-PEG350-NHS ester can be used in drug delivery-related research .
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Cat. No.: HY-177531
CAS No.: 2796227-17-1
S-Ac7-DOG is a cationic lipid with biodegradability, low immunogenicity and high nucleic acid transfection capacity, which is commonly used to construct lipid nanoparticles for nucleic acid molecule delivery. S-Ac7-DOG can bind to mRNA, microRNA and self-amplifying RNA through electrostatic interaction. Lipid nanoparticles formed by S-Ac7-DOG enter cells via an energy-dependent endocytic pathway, release nucleic acid cargos, induce antigen-specific CD8 + T cell responses, promote the generation of precursor memory T cells, and regulate neuroinflammatory pathways. S-Ac7-DOG can be used in the research of retinal diseases, neuroinflammation and cancer .
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Cat. No.: HY-155909
CAS No.: 92451-01-9
Synonyms: mPEG3400-SC; mPEG3400-Succinimidyl ester
Research Areas:  

Others

m-PEG3400-NHS ester (mPEG3400-SC; mPEG3400-Succinimidyl ester) is a polyethylene glycol (PEG)-based biocompatibility-enhancing modifier. m‑PEG3400‑NHS ester enables PEGylation of molecules such as proteins, which reduces the immunogenicity and antigenicity of target molecules, decreases the tendency of protein aggregation, and protects proteins from hydrolysis. m-PEG3400-NHS ester can be used in drug delivery-related research .
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Cat. No.: HY-P1778
CAS No.: 160212-93-1
Target:  

HPV

Research Areas:  

Infection

HPV16 E7 (86-93) is a human leukocyte antigen (HLA)-A2.1 restricted HPV16 E7-derived peptide. HPV16 E7 (86-93) is immunogenic in cervical carcinomas .
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Cat. No.: HY-155909B
CAS No.: 92451-01-9
Synonyms: mPEG550-SC; mPEG550-Succinimidyl ester
Research Areas:  

Others

m-PEG550-NHS ester (mPEG550-SC; mPEG550-Succinimidyl ester) is a polyethylene glycol (PEG)-based biocompatibility-enhancing modifier. m‑PEG550‑NHS ester enables PEGylation of molecules such as proteins, which reduces the immunogenicity and antigenicity of target molecules, decreases the tendency of protein aggregation, and protects proteins from hydrolysis. m-PEG550-NHS ester can be used in drug delivery-related research .
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Cat. No.: HY-157174
Target:  

Others

Research Areas:  

Inflammation/Immunology

Mannosamine-desthiobiotin adduct (compound MDTBA) is a carrier immunogenicity-reducing hapten that reduces the immunogenicity of protein carriers upon conjugation to available free amines on the carrier protein surface. Conjugation of Mannosamine-desthiobiotin adduct to hsIgG significantly (>1-fold) reduced the immunogenicity of hsIgG. Mannosamine-desthiobiotin adduct can be used in antigen design research .
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Cat. No.: HY-172536
Synonyms: mPEG30000-SC; mPEG30000-Succinimidyl ester
Research Areas:  

Others

m-PEG30000-NHS ester (mPEG30000-SC) can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects .
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Cat. No.: HY-P10295
CAS No.: 155314-26-4
Target:  

MDM-2/p53

Research Areas:  

Cancer

p53 (232-240) is a peptide segment of the 232-240 amino acid sequence of the human tumor suppressor protein p53. p53 (232-240) enhances its binding affinity to the Major histocompatibility complex (MHC), thereby enhancing the immunogenicity of this peptide to enhance the immune system's response to tumor antigens. p53 (232-240) can be used in the development of cancer vaccines and in the study of tumor cell recognition and clearance by the immune system .
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Cat. No.: HY-P5471
CAS No.: 204060-45-7
Synonyms: [Leu27]-Melan-A, MART-1 (26-35)
Target:  

Inhibitory Antibodies

Research Areas:  

Others

Melan-A/MART-1 analog ([Leu27]-Melan-A, MART-1 (26-35)) is a biological active peptide. (This Melan-A (26-35) analog, Leu substituted for Ala at position 27, shows better HLA-A*0201 binding properties as well as better immunogenicity and antigenicity than the natural Melan-A (26-35).Pyroglutamyl (pGlu) peptides may spontaneously form when either Glutamine (Q) or Glutamic acid (E) is located at the sequence N-terminus. The conversion of Q or E to pGlu is a natural occurrence and in general it is believed that the hydrophobic γ-lactam ring of pGlu may play a role in peptide stability against gastrointestinal proteases. Pyroglutamyl peptides are therefore considered a normal subset of such peptides and are included as part of the peptide purity during HPLC analysis.)
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Cat. No.: HY-P705686
Purity:  ≥ 85%, as determined by reducing SDS-PAGE .
Synonyms: immunogenic protein MPT64; antigen MPT64; mpt64; MTCY39.39; Rv1980c
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-L172
150 compounds

Immunity refers to the ability of the body to resist the invasion of pathogenic microorganisms and resist a variety of diseases. Immunocompromised will inevitably lead to a series of diseases. Immunopotentiator are a class of compounds that enhance immune function and induce immune response. Immunopotentiator can activate the proliferation and differentiation of one or more kinds of immune active cells in the body, promote the secretion of lymphocytes, and then enhance the immune function of the body. Immunopotentiator are mainly used in the treatment of tumors, infectious diseases and immunodeficiency diseases. In addition, immunopotentiator are often used as adjuvants in combination with vaccine antigens to enhance the immunogenicity of vaccines.

MCE designs a unique collection of 150 compounds with definite or potential Immunopotentiating effect, mainly targeting the NOD-like Receptor (NLR), Toll-like Receptor (TLR), NF-κB, etc. It is an effective tool for development and research of anti-cancer, anti-infectious diseases and anti-immunodeficiency diseases compounds.

Cat. No.: HY-177531S
S-Ac7-DOG is a cationic lipid with biodegradability, low immunogenicity and high nucleic acid transfection capacity, which is commonly used to construct lipid nanoparticles for nucleic acid molecule delivery. S-Ac7-DOG can bind to mRNA, microRNA and self-amplifying RNA through electrostatic interaction. Lipid nanoparticles formed by S-Ac7-DOG enter cells via an energy-dependent endocytic pathway, release nucleic acid cargos, induce antigen-specific CD8+ T cell responses, promote the generation of precursor memory T cells, and regulate neuroinflammatory pathways. S-Ac7-DOG can be used in the research of retinal diseases, neuroinflammation and cancer. S-Ac7-DOg-d4 is the deuterated-labeled S-Ac7-Dog (HY-177531).
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