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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
106 Results for "
interstitial nephritis
" in MedChemExpress (MCE) Product Catalog:
Products (106)
106 Results for "interstitial nephritis" in MCE Product Catalog:
18
18 Publications Verification
Cat. No.: HY-P0299
CAS No.: 283609-79-0
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18
18 Publications Verification
Cat. No.: HY-P0299A
CAS No.: 2828433-17-4
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2
2 Cited Publications
Cat. No.: HY-A0203A
CAS No.: 140207-93-8
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Pentosan Polysulfate Sodium is an orally bioavailable, semi-synthetic medication with anti-inflammatory and pro-chondrogenic properties. Pentosan Polysulfate Sodium also is a potent and selective anti-HIV agent. Pentosan Polysulfate Sodium is used for the treatment of interstitial cystitis .
2
2 Cited Publications
Synonyms: ALXN2050; ACH 0145228; ACH-5228
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Vemircopan (ALXN2050) is an orally active complement factor D (FD) inhibitor. Vemircopan can be used in the research of diseases such as myasthenia gravis, lupus nephritis, IgA nephropathy, and paroxysmal nocturnal hemoglobinuria .
1
1 Cited Publications
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RO5461111 a highly specific and orally active antagonist of Cathepsin S with IC50s of 0.4 nM (human Cathepsin S) and 0.5 nM (murine Cathepsin S), respectively. RO5461111 can effectively inhibit the activation of antigen-specific T cells and B cells. RO5461111 can improve pulmonary inflammation and lupus nephritis .
1
1
1 Cited Publications
Cat. No.: HY-P99177
CAS No.: 2305638-98-4
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1
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Fluorofenidone (AKF-PD) is an orally active compound with anti-fibrotic, antioxidant, and anti-inflammatory pharmacological effects. Fluorofenidone downregulates the expression of ACSL4, upregulates GPX4 expression and inhibits the NF-κB signaling pathway to alleviate inflammation and fibrosis. Fluorofenidone ameliorates cholestasis and fibrosis by inhibiting hepatic Erk/-Egr-1 signaling and Tgfβ1/Smad pathway in mice. Fluorofenidone demonstrates protective effects against chronic lung injury in mice. Fluorofenidone can be used for the study of chronic obstructive pulmonary disease (COPD), pulmonary interstitial fibrosis (PIF) and non-small cell lung cancer (NSCLC) .
1
1 Cited Publications
Cat. No.: HY-P71104
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: RBP3; Retinol-Binding Protein 3; Retinol Binding Protein 3; Retinol-Binding Protein 3, interstitial; IRBP; Retinol Binding Protein 3, interstitial; Interphotoreceptor Retinoid-Binding Protein; interstitial Retinol-Binding Protein 3; D10S64; interstitial R
Species:
Human
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P70250
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MMP1; Matrix Metallopeptidase 1 (interstitial Collagenase); Prev. CLG; Matrix Metalloproteinase 1; interstitial Collagenase; Matrix Metalloprotease 1; Fibroblast Collagenase; Alternative Protein MMP1; Matrix Metalloproteinase 1 (interstitial Collagenase); MMP-1; Matrix Metallopeptidase 1; Matrix Metalloproteinase-1
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P72031
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: RBP4; Retinol-Binding Protein 4, interstitial; Retinol Binding Protein 4; Retinol-Binding Protein 4, Plasma; Plasma Retinol-Binding Protein; Retinol Binding Protein 4, Plasma; Retinol-Binding Protein 4; Retinol-Binding Protein; PRBP; MCOPCB10; RBP; RDCCAS
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P74598
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: RBP4; Retinol-Binding Protein 4, interstitial; Retinol Binding Protein 4; Retinol-Binding Protein 4, Plasma; Plasma Retinol-Binding Protein; Retinol Binding Protein 4, Plasma; Retinol-Binding Protein 4; Retinol-Binding Protein; PRBP; MCOPCB10; RBP; RDCCAS
Species:
Rat
Source:
HEK293
Cat. No.: HY-P990706
CAS No.: 2490217-42-8
Synonyms: ALPN-303
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Synonyms: RTA dh404
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CDDO-dhTFEA (RTA dh404) is a synthetic oleanane triterpenoid compound which potently activates Nrf2 and inhibits the pro-inflammatory transcription factor NF-κB . CDDO-dhTFEA restores hypertension (MAP), increases Nrf2 and expression of its target genes, attenuates activation of NF-κB and transforming growth factor-β pathways, and reduces glomerulosclerosis, interstitial fibrosis and inflammation in the chronic kidney disease (CKD) rats .
Cat. No.: HY-16734A
CAS No.: 942398-84-7
Synonyms: MT-1303 hydrochloride
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Amiselimod (MT-1303) hydrochloride is converted to its active metabolite Amiselimod phosphate by sphingosine kinases in vivo. Amiselimod hydrochloride is an orally active and high selectivity sphingosine 1-phosphate receptor-1 (S1P1) agonist, designed to reduce the bradycardia effects associated with fingolimod and other S1P receptor modulators. Amiselimod hydrochloride inhibits chronic colitis via inhibiting infiltration of colitogenic Th1 and Th17 cells into the colon. Amiselimod hydrochloride inhibits lupus nephritis by reducing the infiltration of autoreactive T cells into the kidneys. Amiselimod hydrochloride is promising for research of autoimmune diseases .
Synonyms: INS-1009
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Treprostinil palmitil is a long-acting inhaled pulmonary vasodilator prodrug of Treprostinil (HY-100441), formulated in a lipid nanoparticle (LNP). Treprostinil palmitil can inhibit pulmonary vascular remodeling induced by Su/Hx challenge in rats. Treprostinil palmitil can induce cough. Treprostinil palmitil demonstrates a sustained presence in the lungs with reduced systemic exposure and prolonged inhibition of hypoxia-induced pulmonary vasoconstriction in vivo. Treprostinil palmitil can be studied in research for pulmonary arterial hypertension and interstitial lung disease .
Category:
Ketones, Aldehydes, Acids Other Diseases Microorganism Endogenous metabolite Disease Research Fields
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Cat. No.: HY-P99316
CAS No.: 1194585-53-9
Synonyms: CNTO-136
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Cat. No.: HY-W010708
CAS No.: 601-34-3
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trans-Ned 19 is a NAADP antagonist and TPC blocker. trans-Ned 19 suppresses the calcium signal and the rat aorta relaxation in response to low histamine concentrations. trans-Ned 19 increases the spontaneous acrosome reaction rate, alleviates anti-CD3 mAb-induced intestinal inflammation, and improves kidney damage in mice with nephrotoxic serum nephritis .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
