country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

6 Results for "

intestinal transit

" in MedChemExpress (MCE) Product Catalog:

Products (6)

Sort by :

Categories

By Targets

Products

N-Methylhistamine dihydrochloride

Cat. No.: HY-101005

CAS No.: 16503-22-3

Synonyms: Nα-Methylhistamine dihydrochloride

Target:

Histamine Receptor Sodium Channel

Research Areas:

Infection

N-Methylhistamine dihydrochloride (Nα-Methylhistamine dihydrochloride) is a non-selective Histamine receptor agonist. N-Methylhistamine dihydrochloride activates histamine H₁, H₂ and H₃ receptors; it stimulates central H₁ receptors by activating sympathetic α and β adrenergic receptors to inhibit intestinal transit, exerts dose-dependent inhibition on intestinal transit, reduces histamine turnover in mouse brains, and increases gastric acid secretion without altering plasma gastrin concentrations. N-Methylhistamine dihydrochloride produces a pH-dependent, voltage-independent potentiating effect on acid-sensing ion channel 1a, and shows no significant activity toward homologous ASIC2a channels. N-Methylhistamine dihydrochloride can be used in studies related to Helicobacter pylori infection .

Compare

Please select quantity

August 31

Get Quote

View All Sizes

Casanthranol

Cat. No.: HY-B2134

CAS No.: 8024-48-4

Category:

Natural Products Metabolic Disease Plants Other Families Extract Disease Research Fields

Target:

α-synuclein

Casanthranol is a naturally derived, orally active mixture of anthraquinone glycosides that exhibits inhibitory activity against α-synuclein and bioactivities related to laxation . Casanthranol inhibits seed-induced α-synuclein fibrillation in cell-free systems and rescues preformed fibril-induced cytotoxicity in differentiated N2a cells. Casanthranol promotes intestinal transit in both the small and large intestines of mice with experimental constipation. Casanthranol can be used in research related to constipation .

Compare