178

D-Lin-MC3-DMA

178 Publications Verification

Cat. No.: HY-112251

CAS No.: 1224606-06-7

Purity: 99.68%

Target:

Liposome

Research Areas:

Others

D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle.

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20

C12-200

20 Cited Publications

Cat. No.: HY-145405

CAS No.: 1220890-25-4

Purity: 99.91%

Target:

Liposome

Research Areas:

Others

C12-200 is a type of ionizable cationic lipid and helper lipid commonly used for mRNA delivery. In the hemophilia B mouse model, mRNA encoding human erythropoietin (EPO) and coagulation factor IX (FIX) can be successfully delivered and expressed using C12-200. C12-200 is utilized in research related to hemophilia B .

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15

Tirapazamine

15 Cited Publications

Cat. No.: HY-13767

CAS No.: 27314-97-2

Purity: 99.02%

Synonyms: SR259075; SR4233; Win59075; SML 0552; SR 259075; Tirazone

Target:

DNA/RNA Synthesis

Research Areas:

Cancer

Tirapazamine (SR259075) is an anticancer agent that shows selective cytotoxicity for hypoxic cells in solid tumors, thereby inducing single-and double-strand breaks in DNA, base damage, and cell death. Tirapazamine is an anticancer and bioreductive agent.Tirapazamine (SR259075) can enhance the cytotoxic effects of ionizing radiation in hypoxic cells .

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14

α-Cyano-4-hydroxycinnamic acid

14 Cited Publications

Cat. No.: HY-107641

CAS No.: 28166-41-8

Purity: 99.92%

Synonyms: α-Cyano-4-hydroxycinnamate

Target:

Monocarboxylate Transporter

Research Areas:

Metabolic Disease

α-Cyano-4-hydroxycinnamic acid (α-Cyano-4-hydroxycinnamate) is a potent and non-competitive inhibitor of monocarboxylate transporters (MCTs). α-Cyano-4-hydroxycinnamic acid inhibits mitochondrial pyruvate transporter with a K_i of 6.3 μM. α-Cyano-4-hydroxycinnamic acid is used as a matrix to facilitate peptide ionization in matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry applications .

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7

CKK-E12

7 Cited Publications

Cat. No.: HY-134781

CAS No.: 1432494-65-9

Purity: ≥98.0%

Target:

Liposome

Research Areas:

Others

CKK-E12 is a ionizable lipid in combination with other lipids make up the lipid nanoparticles which are used to deliver RNA-based research. CKK-E12 is highly selective toward liver parenchymal cell in vivo,

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6

XJB-5-131

6 Cited Publications

Cat. No.: HY-129460

CAS No.: 866404-31-1

Purity: 99.15%

Target:

Reactive Oxygen Species (ROS)

Research Areas:

Neurological Disease

XJB-5-131 is a mitochondria-targeted ROS and electron scavenger . XJB-5-131 is a bi-functional antioxidant that comprises a radical scavenger. XJB-5-131 is a synthetic antioxidant that targets mitochondria . XJB-5-131 is an effective ionizing irradiation protector and mitigator of cord blood mononuclear cells (CB MNCs) .

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