7534 Results for "

isolated

" in MedChemExpress (MCE) Product Catalog:

Products (7534)

Sort by :

Categories

By Targets

Hosts:

Reactivities:

Applications:

Isotypes:

Conjugations:

Clonalities:

Modifications:

Products

179

JC-1 Mitochondrial Membrane Potential Assay Kit

179 Publications Verification

Cat. No.: HY-K0601

MCE JC-1 Mitochondrial Membrane Potential Assay Kit uses JC-1 to detect the mitochondrial membrane potential in variety of cell types, as well as intact tissues and isolated mitochondria.

Please select quantity

August 31

Get Quote

View All Sizes

Berberine sulfate

83 Cited Publications

Cat. No.: HY-N0716B

CAS No.: 633-66-9

Synonyms: Natural Yellow 18 sulfate

Category:

Alkaloids Coptis chinensis Franch. Plants Disease Research Fields Isoquinoline Alkaloids Inflammation/Immunology Ranunculaceae Extract

Target:

Antibiotic Topoisomerase Autophagy Bacterial Reactive Oxygen Species (ROS) Parasite Apoptosis PI3K Akt Caspase JNK AP-1 NF-κB

Berberine sulfate is an alkaloid isolated from the Chinese herbal medicine Huanglian, as an antibiotic. Berberine sulfate induces reactive oxygen species (ROS) generation and inhibits DNA topoisomerase. Berberine sulfate has antineoplastic properties. The sulfate form improves bioavailability .

Compare

Please select quantity

August 31

Get Quote

View All Sizes

Berberine hemisulfate

55 Cited Publications

Cat. No.: HY-N0716A

CAS No.: 316-41-6

Synonyms: Natural Yellow 18 hemisulfate

Category:

Infection Alkaloids Coptis chinensis Franch. Metabolic Disease Plants Disease Research Fields Isoquinoline Alkaloids Cancer Ranunculaceae Extract

Target:

Antibiotic Topoisomerase Autophagy Bacterial Reactive Oxygen Species (ROS) Apoptosis PI3K Akt Caspase JNK AP-1 NF-κB

Berberine hemisulfate is the hemisulfate form of Berberine (HY-N0716). Berberine hemisulfate is an alkaloid isolated from the Chinese herbal medicine Huanglian. Berberine hemisulfate exhibits anti-inflammatory, antibiobic, antitumor, cardiovascular protective and neuroprotective activity .

Compare

Please select quantity

August 31

Get Quote

View All Sizes

Silvestrol

54 Cited Publications

Cat. No.: HY-13251

CAS No.: 697235-38-4

Purity: 99.96%

Synonyms: (-)-Silvestrol

Category:

Agave americana Linn. Natural Products Agavaceae Extract Plants Disease Research Fields Cancer

Target:

Eukaryotic Initiation Factor (eIF) Apoptosis Autophagy

Silvestrol is a eukaryotic translation initiation factor 4A (eIF4A) inhibitor isolated from Agave americana Linn.. Silvestrol induces autophagy and caspase-mediated apoptosis .

Compare

Please select quantity

August 31

Get Quote

View All Sizes

Astragaloside IV

46 Cited Publications

Cat. No.: HY-N0431

CAS No.: 84687-43-4

Category:

Triterpenes Terpenoids Astragalus membranaceus var. mongholicus (Bunge)P.K.Hsiao Leguminosae Extract Plants Disease Research Fields Cancer

Target:

MMP ERK JNK

Astragaloside IV, an active component isolated from Astragalus membranaceus, suppresses the activation of ERK1/2 and JNK, and downregulates matrix metalloproteases (MMP)-2, (MMP)-9 in MDA-MB-231 breast cancer cells.

Compare

Please select quantity

August 31

Get Quote

View All Sizes

Hesperidin

38 Cited Publications

Cat. No.: HY-15337

CAS No.: 520-26-3

Purity: 97.15%

Synonyms: Hesperetin 7-rutinoside

Category:

Rutaceae Extract Flavonoids Anti-aging Flavonones Plants Endogenous metabolite Disease Research Fields Citrus Cancer

Target:

Apoptosis Autophagy Reactive Oxygen Species (ROS) Endogenous Metabolite

Hesperidin (Hesperetin 7-rutinoside), a flavanone glycoside, is isolated from citrus fruits. Hesperidin has numerous biological properties, such as decreasing inflammatory mediators and exerting significant antioxidant effects. Hesperidin also exhibits antitumor and antiallergic activities .

Compare

Please select quantity

August 31

Get Quote

View All Sizes

Artemisinin

34 Cited Publications

Cat. No.: HY-B0094

CAS No.: 63968-64-9

Synonyms: Qinghaosu; NSC 369397

Category:

Infection Piscidia erythrina L. Neurological Disease Terpenoids Sesquiterpenes Plants Compositae Extract Disease Research Fields

Target:

HCV Parasite Akt Ferroptosis

Artemisinin (Qinghaosu), a sesquiterpene lactone, is an anti-malarial agent isolated from the aerial parts of Artemisia annua L. plants . Artemisinin inhibits AKT signaling pathway by decreasing pAKT in a dose-dependent manner. Artemisinin reduces cancer cell proliferation, migration, invasion, tumorigenesis and metastasis and has neuroprotective effects .

Compare

Please select quantity

August 31

Get Quote

View All Sizes

Rocaglamide

34 Cited Publications

Cat. No.: HY-19356

CAS No.: 84573-16-0

Synonyms: Roc-A

Category:

Alkaloids Other Alkaloids Meliaceae Extract Plants Disease Research Fields Aglaia elliptifolia Cancer

Target:

NF-κB HSP Eukaryotic Initiation Factor (eIF)

Rocaglamide (Roc-A) is isolated from the genus Aglaia and can be used for coughs, injuries, asthma and inflammatory skin diseases. Rocaglamide is a potent inhibitor of NF-κB activation in T-cells. Rocaglamide is a potent and selective heat shock factor 1 (HSF1) activation inhibitor with an IC₅₀ of ~50 nM. Rocaglamide inhibits the function of the translation initiation factor eIF4A. Rocaglamide also has anticancer properties in leukemia .

Compare

Please select quantity

August 31

Get Quote

View All Sizes

Oridonin

28 Cited Publications

Cat. No.: HY-N0004

CAS No.: 28957-04-2

Synonyms: NSC-250682; Isodonol

Category:

Infection Terpenoids Diterpenoids Plants Disease Research Fields Inflammation/Immunology Labiatae Extract Butea monosperma Kuntze

Target:

Akt Bacterial Ligands for E3 Ligase

Oridonin (NSC-250682), a diterpenoid isolated from Rabdosia rubescens, acts as an inhibitor of AKT, with IC₅₀s of 8.4 and 8.9 μM for AKT1 and AKT2; Oridonin possesses anti-tumor, anti-bacterial and anti-inflammatory effects.

Compare

Please select quantity

August 31

Get Quote

View All Sizes

Calycosin

24 Cited Publications

Cat. No.: HY-N0519

CAS No.: 20575-57-9

Synonyms: Cyclosin

Category:

Astragalus membranaceus var. mongholicus (Bunge)P.K.Hsiao Leguminosae Extract Plants Other Families Extract Flavonoids Phenols Polyphenols Disease Research Fields Cancer Isoflavones

Target:

Apoptosis

Calycosin is a compound that can be isolated from Radix Astragali. Calycosin has strong antioxidant, anti-inflammatory and apoptosis-modulating effects. Calycosin can be used for the research of ovarian cancer and breast cancer .

Compare

Please select quantity

August 31

Get Quote

View All Sizes

Scutellarin

24 Cited Publications

Cat. No.: HY-N0751

CAS No.: 27740-01-8

Category:

Infection Flavonoids Flavones Phenols Polyphenols Plants Disease Research Fields Medicago truncatula Gaertn. Labiatae Extract

Target:

STAT Akt HIV

Scutellarin, an active flavone isolated from Scutellaria baicalensis, can down-regulates the STAT3/Girdin/Akt signaling in HCC cells, and inhibits RANKL-mediated MAPK and NF-κB signaling pathway in osteoclasts. Scutellarin is active against HIV-1IIIB, HIV-1(74V) and HIV-1KM018 with EC₅₀s of 26 μM, 253 μM and 136 μM, respectively.

Compare

Please select quantity

August 31

Get Quote

View All Sizes

Evodiamine

22 Cited Publications

Cat. No.: HY-N0114

CAS No.: 518-17-2

Synonyms: (+)-Evodiamine; d-Evodiamine

Category:

Rutaceae Extract Alkaloids Piperidine Alkaloids Evodia rutaecarpa (Juss.) Benth. Plants Disease Research Fields Cancer Indole Alkaloids

Target:

Others

Evodiamine is an alkaloid isolated from the fruit of Evodia rutaecarpa Bentham with diverse biological activities including anti-inflammatory, anti-obesity, and antitumor.

Compare

Please select quantity

August 31

Get Quote

View All Sizes

Echinacoside

21 Cited Publications

Cat. No.: HY-N0020

CAS No.: 82854-37-3

Category:

Orobanchaceae Extract Simple Phenylpropanols Cistanche deserticola Ma Phenols Polyphenols Phenylpropanoids Plants

Target:

Wnt Reactive Oxygen Species (ROS)

Echinacoside, one of the phenylethanoids isolated from the stems of Cistanche deserticola, effectively inhibits Wnt/β-catenin signaling. Echinacoside elicits neuroprotection by activating Trk receptors and their downstream signal pathways. Antiosteoporotic activity .

Compare

Please select quantity

August 31

Get Quote

View All Sizes

YM-254890

20 Cited Publications

Cat. No.: HY-111557

CAS No.: 568580-02-9

Purity: ≥95.0%

Category:

Cardiovascular Disease Natural Products Microorganisms Disease Research Fields

Target:

P2Y Receptor

YM-254890 is a selective G_αq/11 protein inhibitor isolated from Chromobacterium sp. YM-254890 shows no inhibition of other G protein subtypes. YM-254890 inhibits platelet aggregation induced by ADP by blocking the P2Y₁ signal transduction pathway, with an IC₅₀ value below 0.6 μM .

Compare

Please select quantity

August 31

Get Quote

View All Sizes

Punicalagin

20 Cited Publications

Cat. No.: HY-N0063

CAS No.: 65995-63-3

Category:

Infection Punica granatum L. Punicaceae Extract Metabolic Disease Phenols Polyphenols Plants Disease Research Fields

Target:

SARS-CoV HBV

Punicalagin is a polyphenol ingredient isolated from Pomegranate (Punica granatum L.) or the leaves of Terminalia catappa L.. Punicalagin is a reversible and non-competitive 3CL ^pro inhibitor and inhibits SARS-CoV-2 replication in vitro. Punicalagin is an anti-hepatitis B virus (HBV) agent and has antioxidant, anti-inflammatory, and anticancer effects. Punicalagin has the potential for the research of COVID-19 .

Compare

Please select quantity

August 31

Get Quote

View All Sizes

Liquiritin

19 Cited Publications

Cat. No.: HY-N0376

CAS No.: 551-15-5

Category:

Neurological Disease Leguminosae Extract Plants Flavonoids Monophenols Flavonones Phenols Disease Research Fields Glycyrrhiza uralensis Fisch. Inflammation/Immunology

Liquiritin, a flavonoid isolated from Glycyrrhiza uralensis, is a potent and competitive AKR1C1 inhibitor with IC₅₀s of 0.62 μM, 0.61 μM, and 3.72μM for AKR1C1, AKR1C2 and AKR1C3, respectively. Liquiritin efficiently inhibits progesterone metabolism mediated by AKR1C1 in vivo . Liquiritin acts as an antioxidant and has neuroprotective, anti-cancer and anti-inflammatory activity .

Compare

Please select quantity

August 31

Get Quote

View All Sizes

Baohuoside I

18 Cited Publications

Cat. No.: HY-N0011

CAS No.: 113558-15-9

Synonyms: Icariin-II; Icariside-II

Category:

Flavonols Anti-aging Plants Endogenous metabolite Human Gut Microbiota Metabolites Flavonoids Epimedium koreanum Nakai Phenols Polyphenols Disease Research Fields Inflammation/Immunology Endocrinology Berberidaceae Extract Cancer

Target:

CXCR Apoptosis

Baohuoside I, a flavonoid isolated from Epimedium koreanum Nakai, acts as an inhibitor of CXCR4, downregulates CXCR4 expression, induces apoptosis and shows anti-tumor activity.

Compare

Please select quantity

August 31

Get Quote

View All Sizes

Piperine

18 Cited Publications

Cat. No.: HY-N0144

CAS No.: 94-62-2

Synonyms: Bioperine; 1-Piperoylpiperidine

Category:

Piperaceae Extract Plants Endogenous metabolite Piper nigrum Linn. Biological Pesticide Research Agricultural Research Alkaloids Piperidine Alkaloids Disease Research Fields Cancer

Target:

Environmental Pollutants Endogenous Metabolite Autophagy P-glycoprotein

Piperine is an alkaloid, can be isolated from pepper. Piperine can inhibit the activity of P-glycoprotein and CYP3A4. Piperine inhibits HeLa cells with an IC₅₀ of 61.94±0.054 μg/mL .

Compare

Please select quantity

August 31

Get Quote

View All Sizes

[6]-Gingerol

17 Cited Publications

Cat. No.: HY-14615

CAS No.: 23513-14-6

Purity: 99.68%

Synonyms: (S)-(+)-[6]Gingerol

Category:

Zingiber officinale Roscoe Monophenols Zingiberaceae Extract Phenols Plants Disease Research Fields Cancer

Target:

AMPK Apoptosis

[6]-Gingerol is an active compound isolated from Ginger (Zingiber officinale), exhibits a variety of biological activities including anticancer, anti-inflammation, and anti-oxidation.

Compare

Please select quantity

August 31

Get Quote

View All Sizes

Kifunensine

17 Cited Publications

Cat. No.: HY-19332

CAS No.: 109944-15-2

Synonyms: FR-900494

Category:

Alkaloids Piperidine Alkaloids Microorganisms Disease Research Fields Inflammation/Immunology

Target:

Glycosidase

Kifunensine, a potent and selective inhibitor of class I α-mannosidases isolated from Actinomycete, prevents α-mannosidases I from trimming mannose residues on glycoproteins. Kifunensine inhibits ERAD .

Compare

Please select quantity

August 31

Get Quote

View All Sizes

Type


Products	/ In-stock - + Please select quantity Expand Add to Cart
Cat. No.
Purity
Feature
CAS No.
Storage
Solvent & Solubility
Appearance
Formulation
Species
Source
Tag
Endotoxin Level
Biological Activity
Storage & Stability
Shipping
Host
Reactivity
Dilution Ratio
Conjugation
Clonality
Immunogen
SwissProt ID
Initial Source
Emission (Em)
Excitation (Ex)
Sequence Shortening
Isotype
Gene ID
Accession
Application
Reconsititution
Molecular Weight
Enzyme Activity
Specific Activity
In Vitro
In Vivo
Size	/ In-stock - + Add to Cart Bulk Inquiry Please select quantity

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

Product Name:
CAS No.:
Species:
Purity:
Quantity: