48 Results for "

isomerization

" in MedChemExpress (MCE) Product Catalog:
Products (48)

48 Results for "isomerization" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-W004500
CAS No.: 116-31-4
All-trans-retinal is an vitamin A metabolite in the retina, and is produced following photo-isomerization of the visual chromophore 11-cis-Retinal. All-trans-retinal is cleared from photoreceptors by ATP-binding cassette transporter (ABCA4) and all-trans-retinol dehydrogenase (RDH). All-trans-retinal induces Bax activation via DNA damage to mediate retinal cell apoptosis .
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1
1 Cited Publications
Cat. No.: HY-113478
CAS No.: 78919-26-3
Purity:  99.90%
Synonyms: Isoursodeoxycholic acid
Target:  

Others

Research Areas:  

Metabolic Disease

3β-Ursodeoxycholic acid (Isoursodeoxycholic acid) is a bile acid. 3β-Ursodeoxycholic acid shows good tolerance and well intestinal absorption by oral adminstation. 3β-Ursodeoxycholic acid can be isomerized by intestinal and hepatic enzymes to yield UDCA .
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1
1 Cited Publications
Cat. No.: HY-116716
CAS No.: 680622-70-2
Purity:  98.54%
Target:  

MicroRNA

Research Areas:  

Cancer

PIN1 inhibitor API-1 is a specific Pin1 (peptidyl-prolyl cis-trans isomerase NIMA-interacting 1) inhibitor (API-1) with an IC50 of 72.3 nM. PIN1 inhibitor API-1 directly and specifically binds to the Pin1 peptidyl-prolyl isomerase (PPIase) domain and potently inhibits Pin1 cis-trans isomerizing activity. PIN1 inhibitor API-1 retains the active conformation of pXPO5 and restores the ability of pXPO5 to transport pre-miRNAs from nucleus to cytoplasm, thus up-regulating the anticancer miRNA biogenesis to suppress both in vitro and in vivo hepatocellular carcinoma development .
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Cat. No.: HY-19720A
CAS No.: 1141934-97-5
Synonyms: ACU-4429 hydrochloride
Target:  

RPE65

Research Areas:  

Metabolic Disease

Emixustat (ACU-4429) hydrochloride is an orally active RPE65 inhibitor with an IC50 value of 4.4 nM. Emixustat hydrochloride is also a visual cycle modulator, capable of regulating visual cycle activity by inhibiting retinol isomerization, and holds potential for studying vision disorders such as age-related macular degeneration (AMD) .
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Cat. No.: HY-19720
CAS No.: 1141777-14-1
Synonyms: ACU-4429
Target:  

RPE65

Research Areas:  

Metabolic Disease

Emixustat is an orally active RPE65 inhibitor with an IC50 value of 4.4 nM. Emixustat is also a visual cycle modulator, capable of regulating visual cycle activity by inhibiting retinol isomerization, and holds potential for studying vision disorders such as age-related macular degeneration (AMD) .
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Cat. No.: HY-156004
CAS No.: 2399497-60-8
Purity:  99.62%
Target:  

Bacterial

Research Areas:  

Others

Ziapin 2 is a membrane potential modulator and an intracellular membrane photoactuator. Ziapin 2 binds to the bacterial plasma membrane, and upon embedding into the lipid bilayer, undergoes trans-cis isomerization under 470 nm light irradiation, which triggers membrane potential hyperpolarization and induces the opening of ion channels on bacterial cell membranes. Through interactions with lipids, Ziapin 2 increases the overall flexibility of the lipid bilayer. Ziapin 2 can form photosensitive transmembrane dimers to trigger cellular signal transduction. Ziapin 2 is applicable to the research and regulation of bacterial electrical signal transduction and the regulation of membrane physical properties .
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Cat. No.: HY-E70308
CAS No.: 9055-00-9
Target:  

Endogenous Metabolite

Research Areas:  

Others

Glucose isomerase (immobilized) is glucose isomerase, which catalyzes the reversible isomerization of D-glucose and D-xylose into D-fructose and D-xylulose, respectively. Glucose isomerase (immobilized) can be used to produce fructose syrup under high-temperature conditions above 90 ℃. Glucose isomerase (immobilized) is widely distributed in prokaryotes .
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Cat. No.: HY-W007333
CAS No.: 42196-31-6
Research Areas:  

Others

Palladium trifluoroacetate is a catalyst. Palladium trifluoroacetate catalyzes the conversion of substituted cyclohexenes to aromatic products and mediates the dechlorination of 3-chlorocyclohexene. Palladium trifluoroacetate mediates the heterogeneous isomerization of 1-hexene, a reaction that is inhibited by molecular oxygen. Palladium trifluoroacetate participates in the stoichiometric conversion of tetralin to naphthalene at elevated temperatures .
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Cat. No.: HY-P2918
CAS No.: 9001-41-6
Synonyms: GPI; Phosphoglucose Isomerase
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease Cancer

Phosphoglucose Isomerase, Rabbit muscle (GPI), i.e., phosphoglucose isomerase/phosphoglucoisomerase (PGI) or phosphohexose isomerase (PHI), is often used in biochemical studies. Glucose 6-phosphate isomeras is a highly conserved glycolytic and dimeric enzyme. Glucose 6-phosphate isomeras catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate .
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Cat. No.: HY-W654334
9-cis-Retinol-d5 is the deuterated-labeled 9-cis Retinol (HY-W587806). 9-cis Retinol is an upstream precursor of 9-cis-Retinal (HY-W009310) and 9-cis-Retinoic acid (HY-15128). 9-cis Retinol serves as a reaction substrate for cRDH, ARAT and LRAT, participates in cellular uptake and isomerization processes, and can be oxidized to form 9-cis-Retinal in the biosynthetic pathway. 9-cis Retinol inhibits the activity of 9-cis retinaldehyde dehydrogenase, thereby blocking the biosynthesis of 9-cis-Retinoic acid. 9-cis Retinol is applicable for metabolism-related research .
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Cat. No.: HY-148124
CAS No.: 3219-99-6
Target:  

Drug Isomer

Research Areas:  

Others

6-epi Doxycycline is an epimer of Doxycycline (HY-N0565), produced as a degradation product through the isomerization of Doxycycline under abnormal conditions (such as high temperature, pH changes, or humidity). 6-epi Doxycycline is commonly used for the detection and analysis of impurity content in pharmaceutical formulations .
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Cat. No.: HY-CE02017A
CAS No.: 30802-02-9
Synonyms: Feruloyl-coenzyme A
Target:  

Drug Intermediate

Research Areas:  

Others

Feruloyl-CoA (Feruloyl-coenzyme A) is a cinnamoyl-CoA ester substrate involved in the biosynthesis of lignin and coumarin in plants. Feruloyl-CoA acts as a substrate for cinnamoyl-CoA reductase 1-dependent reduction reaction with NADPH to produce cinnamaldehyde. Feruloyl-CoA is a precursor that generates Scopoletin (HY-N0342) via spontaneous trans/cis isomerization and lactonization of its side chain .
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Cat. No.: HY-100072
CAS No.: 51544-64-0
Synonyms: Methyl (2E,4E,6Z)-decatrienoate
Target:  

Sex Pheromone

Research Areas:  

Infection

(2E,4E,6Z)-Methyl deca-2,4,6-trienoate (Methyl (2E,4E,6Z)-decatrienoate) is the aggregation pheromone of the brown-winged green bug, Plautia stali. (2E,4E,6Z)-Methyl deca-2,4,6-trienoate exposed to daylight in solutions and/or on dispensers used for field trapping can readily isomerize to form complex mixtures of isomers, thus causing a concern about lure stability and longevity .
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Cat. No.: HY-W027631
CAS No.: 6117-80-2
Research Areas:  

Infection

cis-2-Butene-1,4-diol serves as a probe for investigating isomerization and hydrogenation/hydrogenolysis reactions. cis-2-Butene-1,4-diol is also a compound used in the synthesis of the antiviral agent Oxetanocin A. cis-2-Butene-1,4-diol undergoes hydrogenation and hydrogenolysis reactions over supported platinum catalysts, with negligible levels of isomerization .
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Cat. No.: HY-121231R
CAS No.: 501-16-6
trans-Caffeic acid (Standard) is the analytical standard of trans-Caffeic acid (HY-121231). This product is intended for research and analytical applications. trans-Caffeic acid is a hydroxycinnamic acid widely distributed in coffee, propolis, and Lamiaceae herbs. trans-Caffeic acid exhibits significant antioxidant and photoprotective activities, and can be used in cancer-related research. trans-Caffeic acid readily undergoes reversible isomerization to form its cis-isomer in protic solvents, under high temperature, ultraviolet radiation, and stress conditions. Binding of trans-Caffeic acid with aluminum, lead, or copper ions attenuates isomerization and inhibits the formation of vinylcatechol, while complexation with lead or copper ions also promotes the formation of aesculetin .
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Cat. No.: HY-E70022
CAS No.: 9031-25-8
Target:  

Others

Research Areas:  

Others

D-Mannose isomerase (PsMaSeAF) is a carbohydrate isomerase catalyzing the reversible isomerization of d-mannose to d-fructose. D-Mannose isomerase (PsMaSeAF) belongs to the N-acylglucosamine 2-epimerase (AGE) superfamily along with AGE, cellobiose 2-epimerase (CE), and aldose-ketose isomerase (AKI) .
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Cat. No.: HY-W587806
CAS No.: 22737-97-9
Target:  

Endogenous Metabolite

Research Areas:  

Inflammation/Immunology

9-cis Retinol is an upstream precursor of 9-cis-Retinal (HY-W009310) and 9-cis-Retinoic acid (HY-15128). 9-cis Retinol serves as a reaction substrate for cRDH, ARAT and LRAT, participates in cellular uptake and isomerization processes, and can be oxidized to form 9-cis-Retinal in the biosynthetic pathway. 9-cis Retinol inhibits the activity of 9-cis retinaldehyde dehydrogenase, thereby blocking the biosynthesis of 9-cis-Retinoic acid. 9-cis Retinol is applicable for metabolism-related research .
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Cat. No.: HY-W583685
CAS No.: 3343-30-4
Research Areas:  

Others

1-Oleoyl-3-palmitoylglycerol is an isomerization byproduct in the preparation of diacylglycerol .
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Cat. No.: HY-W216621
CAS No.: 605-91-4
Pinacyanol iodide is a fluorescent cyanine dye. Pinacyanol iodide exhibits ultrafast excited state isomerization .
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Cat. No.: HY-P2918A
CAS No.: 9001-41-6
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

Phosphoglucose isomerase, bacillus stearothermophilus is a highly conserved glycolytic and dimeric enzyme. Phosphoglucose isomerase, bacillus stearothermophilus catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate .
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